Ji Liu, MD, MS
Associate Professor TermCards
About
Research
Publications
2026
Quality Analysis of YouTube and Facebook Videos for Glaucoma Treatment Options
Sarrafpour S, Maheshwari A, Lee J, Young B, Liu J, Teng C. Quality Analysis of YouTube and Facebook Videos for Glaucoma Treatment Options. Clinical Ophthalmology 2026, 20: 575279. PMID: 41809204, PMCID: PMC12970006, DOI: 10.2147/opth.s575279.Peer-Reviewed Original ResearchGlaucoma treatment optionsTreatment optionsFacebook videosYouTube videosMedical treatment optionsVideo quality scoreQuality of videoGoal of treatmentUntreated diseaseEye pressureGlaucomaAnalysis of YouTubePatientsKappa valuesIndependent reviewersComprehensive searchVideoInter-rater reliabilityEducating patientsHigher accuracyMedical informationTreatmentFacebookYouTubeQuality analysis
2025
Surgical Outcome Comparison of Open Conjunctival Ab Externo Xen 45 Gel Stent Implantation vs Trabeculectomy in Open-angle Glaucoma
Applebaum S, Hundito A, Teng C, Sarrafpour S, Liu J. Surgical Outcome Comparison of Open Conjunctival Ab Externo Xen 45 Gel Stent Implantation vs Trabeculectomy in Open-angle Glaucoma. JOURNAL OF CURRENT GLAUCOMA PRACTICE 2025, 19: 158-167. PMID: 41523177, PMCID: PMC12780353, DOI: 10.5005/jp-journals-10078-1493.Peer-Reviewed Original ResearchQuantification and Analysis of Laser Peripheral Iridotomies in the United States from 2000 to 2021
Maheshwari A, Sarrafpour S, Jayaram R, Liu J, Teng C. Quantification and Analysis of Laser Peripheral Iridotomies in the United States from 2000 to 2021. JOURNAL OF CURRENT GLAUCOMA PRACTICE 2025, 19: 208-215. PMID: 41523167, PMCID: PMC12780361, DOI: 10.5005/jp-journals-10078-1502.Peer-Reviewed Original Research
2024
Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future Directions
Banou L, Sarrafpour S, Teng C, Liu J. Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future Directions. The Yale Journal Of Biology And Medicine 2024, 97: 491-503. PMID: 39703610, PMCID: PMC11650918, DOI: 10.59249/hwid7537.Peer-Reviewed Original ResearchConceptsAdeno-associated virusOcular gene therapyGene therapyFood and Drug AdministrationViral vectorsImmune responsePotential application of gene therapyClinical trialsApproval of voretigene neparvovecViral vector-based therapyApplication of gene therapyImproved delivery techniquesVector-based therapyImmune-privileged statusInduce Immune ResponsesReduced immune responseVoretigene neparvovecContralateral eyeRetinal dystrophyImmune privilegeOcular diseasesDeliver genesEye diseaseTherapeutic efficacyTherapyExternal Disruption of Ocular Development in Utero
Kim H, Sarrafpour S, Teng C, Liu J. External Disruption of Ocular Development in Utero. The Yale Journal Of Biology And Medicine 2024, 97: 41-48. PMID: 38559457, PMCID: PMC10964818, DOI: 10.59249/rrmm8911.Peer-Reviewed Original ResearchConceptsOcular developmentOcular embryologyEnglish-language articlesIntrauterine infectionMaternal nutritionClinical significanceGenetic signaling pathwaysWeb of ScienceAnimal modelsHormonal factorsHuman studiesMultifactorial naturePregnancySignaling pathwayGoogle ScholarReviewIntrauterineEmbryologyLimited resourcesGestationUteroPathophysiologyFactorsInfectionPubMed
2023
Ahmed ClearPath, PAUL Glaucoma Implant, and Aurolab Aqueous Drainage Implant
Fliney G, Teng C, Liu J, Sarrafpour S. Ahmed ClearPath, PAUL Glaucoma Implant, and Aurolab Aqueous Drainage Implant. Current Practices In Ophthalmology 2023, 295-309. DOI: 10.1007/978-981-99-1661-0_16.Peer-Reviewed Original ResearchTube placementUsual clinical evaluationPresence of neovascularizationPeripheral anterior synechiaeCombined cataract surgeryAnterior chamber depthGlaucoma drainage deviceGlaucoma interventionRefractory glaucomaLens statusAnterior synechiaePhakic eyesGlaucoma patientsGlaucoma surgeryPatient selectionPreoperative examinationCataract surgeryPseudophakic eyesClinical examinationClinical evaluationCorneal healthAqueous drainageChamber depthGlaucoma implantHigh riskAcute Pain Management Protocol for Ophthalmic Procedures
Dhodapkar R, Jin A, Liu J. Acute Pain Management Protocol for Ophthalmic Procedures. 2023, 291-311. DOI: 10.1007/978-3-031-21291-8_18.ChaptersMotor nerve blockNerve blockOphthalmic proceduresPost-procedural painPain management protocolPostoperative painMaxillary divisionRetrobulbar injectionCardiac injuryTrigeminal nerveFacial nerveExtraocular musclesLocal anestheticsTenon's blockOculoplastic proceduresTrigeminovagal reflexGold standardPainAnesthesiaNerveManagement protocolExtra careOculocardiacBradycardiaAkinesiaKahook Dual Blade versus Trabectome (KVT): Comparing Outcomes in Combination with Cataract Surgery
Fliney G, Kim E, Sarwana M, Wong S, Tai T, Liu J, Sarrafpour S, Chadha N, Teng C. Kahook Dual Blade versus Trabectome (KVT): Comparing Outcomes in Combination with Cataract Surgery. Clinical Ophthalmology 2023, 17: 145-154. PMID: 36647517, PMCID: PMC9840398, DOI: 10.2147/opth.s391527.Peer-Reviewed Original ResearchKahook Dual BladeKDB groupIntraocular pressureCataract surgeryGlaucoma medicationsDual BladeIncidence of hyphemaRetrospective chart reviewPercentage of eyesMedication burdenChart reviewAdverse eventsCommon complicationIOP reductionMonth 12Surgical successComparing outcomesMean changeTrabectomeMedicationsAcademic centersSurgeryMmHgGreater decreasePOM12
2022
Corticosteroid-Induced Glaucoma
Liu J, Arrigg C. Corticosteroid-Induced Glaucoma. 2022, 2541-2560. DOI: 10.1007/978-3-030-42634-7_183.Peer-Reviewed Original ResearchPrimary open-angle glaucomaCorticosteroid-induced glaucomaOpen-angle glaucomaCorticosteroid useOcular hypertensionAngle glaucomaCorticosteroid-induced ocular hypertensionIntraocular pressure elevationEffect of corticosteroidsRoute of administrationSecondary glaucomaClinical coursePressure elevationSystemic disordersRisk factorsFamily historyEffective treatmentOutflow facilityGlaucomaOcular tissuesTrabecular meshworkCareful monitoringIntracellular alterationsHypertensionCorticosteroids
2021
Chapter 17 Epigenetics in ocular medicine
Liu J. Chapter 17 Epigenetics in ocular medicine. 2021, 347-373. DOI: 10.1016/b978-0-12-823928-5.00003-7.Peer-Reviewed Original ResearchOcular medicineEye diseaseDevelopment of eye disordersRisk factorsOcular disease developmentEpithelial-mesenchymal transitionOcular developmentEye disordersChromatin remodelingDNA methylationEnvironmental risk factorsEpigenetic alterationsEpigenetic modificationsHistone alterationsRegulatory pathwaysGenetic controlDisease pathogenesisGene expressionIntracellular signalingSignaling pathwayTherapeutic targetClinical implicationsCell proliferationOxidative stressRNA changes
Academic Achievements & Community Involvement
Clinical Care
Overview
Ji Liu, MD, MS, is an ophthalmologist who specializes in the medical and surgical management of glaucoma, routine and complex cataract surgery, and anterior segment surgery (surgery performed on the iris and lens).
Dr. Liu says he was drawn to medicine because he wanted to understand how and why people get sick, and how to manage it. “In medical school, I realized the importance of vision,” he says. “Ninety percent of what we learn from the outside world every day comes from our eyes. And the advances in technology that we now have for treating eye diseases are fascinating.”
For example, with cataract surgery, intraocular lens implantation can correct not just the cataract but astigmatism. Newer intraocular lens technology may even help patients seeing well for both near and far distance without need for glasses. For glaucoma, there is no cure, but there are many treatments, including modern laser and microinvasive procedures, in addition to traditional therapy, Dr. Liu says.
Dr. Liu says the best parts of his job are helping patients see and improving their quality of life. “I follow many of my patients for years and it’s rewarding to either stop the progression of their disease or restore their vision,” he says. “For surgery, I enjoy both the routine and the complex surgeries, like cataract surgery, dislocated lens repair, iris repair, and the glaucoma procedures with new technologies.”
When a patient comes to see him for the first time, Dr. Liu says he takes the time to understand their concerns and gather their medical history. “I also tend to not just focus on the eye, but ask them about their support system at home. For someone with low vision, I want to find out if they have difficulty using drops or any assistance is needs for daily living,” he says.
Dr. Liu’s research focuses on intraocular pressure monitoring, as high pressure is a major risk factor for glaucoma. His research also involves laser and surgical treatment of glaucoma. Dr. Liu believes research is ultimately the key to improve patient care and treatment outcome.
Clinical Specialties
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Glaucoma
Learn More on Yale MedicineOcular Hypertension
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