Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsLeora Horwitz, MD, MHS
About
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Biography
Leora Horwitz, MD is a general internist who studied social science as an undergraduate and is now a clinician researcher focused on quality and safety in healthcare. In particular, she focuses on systems and practices intended to bridge gaps or discontinuities in care. She has studied shift-to-shift transfers among physicians and among nurses, transfers from the emergency department to inpatient units, and the transition from the hospital to home. She is currently adjunct faculty at Yale; her primary work is at NYU Langone Health, where she directs the Center for Healthcare Innovation and Delivery Science and the division of healthcare delivery science in the Department of Population Health. Her current work is focused primarily on developing a learning health system through innovations in clinical delivery and in data capture and analysis.
Departments & Organizations
- Internal Medicine
- Yale Ventures
- Yale-New Haven Hospital Primary Care Center
Education & Training
- Fellow
- Yale University School of Medicine (2007)
- MHS
- Yale School of Medicine (2006)
- Chief Resident
- Mount Sinai Hospital (2004)
- Resident
- Mount Sinai Hospital (2003)
- MD
- Harvard Medical School (2000)
- BA
- Harvard University (1996)
Research
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Overview
Medical Research Interests
ORCID
0000-0003-1800-6040
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Jeph Herrin, PhD
Huihui Yu, PhD
Joseph Ross, MD, MHS
Serena Susan Spudich, MD, MA
Arjun Venkatesh, MD, MBA, MHS
Faseeha Altaf, MPH
Quality of Health Care
Publications
2025
Associations between readmission disparities and hospital equity efforts: an analysis of U.S. hospitals
Nash K, Adler R, Yu H, Herrin J, Weerahandi H, Horwitz L, Weissman J. Associations between readmission disparities and hospital equity efforts: an analysis of U.S. hospitals. BMC Health Services Research 2025 PMID: 41366671, DOI: 10.1186/s12913-025-13874-4.Peer-Reviewed Original ResearchConceptsCenters for Medicare and Medicare ServicesReadmission disparitiesEquity effortsMedicare beneficiariesEquity officersAmerican Hospital Association Annual SurveyHospital-level disparitiesComposite scoreHospital-levelHealthcare deliveryHospital cultureHospital covariatesMedicare dataHospital dataU.S. hospitalsUS hospitalsMedicare servicesUnadjusted analysisMedicare readmissionsPolicy questionsMedicareReadmission ratesOrganizational typesDisparitiesReadmissionA Target Trial Emulation Study of SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Combination Therapy in Preventing Kidney Failure in Type 2 Diabetes.
Blum M, Mehta S, Surapaneni A, Carrero J, Zhang D, Inker L, Horwitz L, Blecker S, Shin J, Grams M. A Target Trial Emulation Study of SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Combination Therapy in Preventing Kidney Failure in Type 2 Diabetes. Clinical Journal Of The American Society Of Nephrology 2025 PMID: 41400456, DOI: 10.2215/cjn.0000000902.Peer-Reviewed Original ResearchAltmetricConceptsSodium-glucose cotransporter 2 inhibitorsGlucagon-like peptide-1 receptor agonistsSodium-glucose cotransporter 2Glucagon-like peptide-1Risk of kidney failurePeptide-1 receptor agonistsType 2 diabetesCombination therapyReceptor agonistsKidney failureLow riskCotransporter 2Heart failureEffects of sodium-glucose cotransporter 2GLP-1 receptor agonistsIncident kidney failureYears of follow-upProgression to kidney failureCox proportional hazards regression modelsOptum Labs Data WarehouseHigh-risk patientsInverse probabilityProportional hazards regression modelsIntention-to-treat analysisInverse probability of treatmentLong COVID trajectories in the prospectively followed RECOVER-Adult US cohort
Thaweethai T, Donohue S, Martin J, Hornig M, Mosier J, Shinnick D, Ashktorab H, Atieh O, Blomkalns A, Brim H, Chen Y, Cortez M, Erdmann N, Flaherman V, Goepfert P, Goldman J, Hamburg N, Han J, Heath J, Jacoby V, Jolley S, Kelly J, Kelly S, Kim C, Krishnan J, Letts R, Levitan E, Modes M, McComsey G, Metz T, Mullington J, Ofotokun I, Okumura M, Paredes C, Patterson T, Peluso M, Reece R, Sherif Z, Simhan H, Simmons C, Singh U, Taylor B, Taylor B, Trinity J, Troxel A, Utz P, Vasey A, Weinberger E, Wiley Z, Wisnivesky J, Yee L, Horwitz L, Foulkes A, Levy B. Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort. Nature Communications 2025, 16: 9557. PMID: 41249167, PMCID: PMC12623977, DOI: 10.1038/s41467-025-65239-4.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsLong COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During Pregnancy Compared With Outside of Pregnancy.
Metz T, Reeder H, Clifton R, Flaherman V, Aragon L, Baucom L, Beamon C, Braverman A, Brown J, Carmilani M, Cao T, Chang A, Costantine M, Dionne J, Gibson K, Gross R, Guerreros E, Habli M, Hess R, Hillier L, Hodder S, Hoffman M, Hoffman M, Huang W, Hughes B, Jia X, Kale M, Katz S, Laleau V, Mendez-Figueroa H, McComsey G, Ofotokun I, Okumura M, Pacheco L, Palatnik A, Palomares K, Parry S, Pettker C, Plunkett B, Poppas A, Ramsey P, Reddy U, Rouse D, Saade G, Sandoval G, Sciurba F, Simhan H, Skupski D, Sowles A, Thorp J, Tita A, Wiegand S, Weiner S, Yee L, Horwitz L, Foulkes A, Jacoby V. Long COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During Pregnancy Compared With Outside of Pregnancy. Obstetrics And Gynecology 2025 PMID: 41037811, DOI: 10.1097/aog.0000000000006067.Peer-Reviewed Original ResearchAltmetricConceptsSARS-CoV-2 infectionSARS-CoV-2Severe acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Adjusted riskIndex infectionRespiratory syndrome coronavirus 2Multicenter observational cohort studySyndrome coronavirus 2Observational cohort studyOmicron variantOmicron variants of severe acute respiratory syndrome coronavirus 2Coronavirus 2Propensity score matchingMedian ageCohort studyPregnancyLong COVIDPrimary outcomeAcquisition of SARS-CoV-2Variants of severe acute respiratory syndrome coronavirus 2Risk of long COVIDIndex scoreScore matchingInfectionA Drug-wide Association Study on Medications Associated With Cystatin C–Estimated GFR
Inker L, Mehta S, Chang A, Blecker S, Blum M, Faucon A, Flaherty C, Horwitz L, Surapaneni A, Shin J, Xu Y, Grams M, Carrero J. A Drug-wide Association Study on Medications Associated With Cystatin C–Estimated GFR. American Journal Of Kidney Diseases 2025, 86: 860-864. PMID: 40914545, PMCID: PMC12580976, DOI: 10.1053/j.ajkd.2025.06.018.Peer-Reviewed Original ResearchCitationsAltmetricAge‐Related Changes in the Clinical Picture of Long COVID
Fain M, Horne B, Horwitz L, Thaweethai T, Greene M, Hornig M, Orkaby A, Rosen C, Ritchie C, Ashktorab H, Blachman N, Brim H, Emerson S, Erdmann N, Erlandson K, de Erausquin G, Fong T, Geng L, Gordon H, Gully J, Hadlock J, Han J, Huang W, Jagannathan P, Kelly J, Klein J, Krishnan J, Levitan E, McComsey G, McDonald D, Montgomery A, O'Brien L, Ofotokun I, Patterson T, Peluso M, Pemu P, Perlowski A, Reiman E, Sanon M, Seshadri S, Shellito J, Sherif Z, Shikuma C, Singer N, Singh U, Trinity J, Wisnivesky J, Witvliet M, Foulkes A, Nikolich J, consortium T. Age‐Related Changes in the Clinical Picture of Long COVID. Journal Of The American Geriatrics Society 2025, 73: 3123-3137. PMID: 40888500, DOI: 10.1111/jgs.70043.Peer-Reviewed Original ResearchAltmetricConceptsOlder adultsPrevalent symptomsCommunity-dwelling older adultsLong COVIDCommunity-dwelling participantsPost-acute sequelaeSelf-reported symptomsSymptom prevalence ratesPost-exertional malaiseHearing lossSymptoms of long COVIDPost-acute sequelae of SARS-CoV-2Symptom clustersPrevalence ratesClinical pictureObservational studySleep disturbanceAdultsImpact of ageParticipantsSymptomsAgeAge-related changesCluster 3Age-related shiftDesign-based provider profiling with artificial intelligence to enhance quality and equity in health care delivery
Wu W, Díaz I, Horwitz L. Design-based provider profiling with artificial intelligence to enhance quality and equity in health care delivery. Health Services And Outcomes Research Methodology 2025, 1-15. DOI: 10.1007/s10742-025-00355-8.Peer-Reviewed Original ResearchCitationsConceptsArtificial intelligenceHealth care deliveryProvider profilingCare deliveryEffectiveness of health care deliveryNatural language processingData privacy concernsHealth care qualityPrivacy concernsAlgorithmic disparitiesLanguage processingMachine learningCare qualityPerformance benchmarksInflexible modelsProvidersProfile objectsIntelligenceHealthCost-effectiveInadequate attentionDeliveryEvidence-based accountBenchmarksReimagining Cardiovascular Screening Leveraging Detection for Population Health Impact
Berman A, Mukhopadhyay A, Blecker S, Horwitz L. Reimagining Cardiovascular Screening Leveraging Detection for Population Health Impact. Journal Of The American College Of Cardiology 2025, 86: 959-961. PMID: 40992822, DOI: 10.1016/j.jacc.2025.07.047.Peer-Reviewed Original ResearchAltmetricTitration and discontinuation of semaglutide for weight management in commercially insured US adults
Xu Y, Carrero J, Chang A, Inker L, Zhang D, Mukhopadhyay A, Blecker S, Horwitz L, Grams M, Shin J. Titration and discontinuation of semaglutide for weight management in commercially insured US adults. Obesity 2025, 33: 1243-1248. PMID: 40464214, PMCID: PMC12213178, DOI: 10.1002/oby.24315.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDose escalation scheduleHigher discontinuation rateDiscontinuation ratesWeight managementMultivariate Cox regressionUS adultsAssociated with discontinuationCommercially insured adultsEarly discontinuationAssociated with low household incomeCox regressionSemaglutideLowest quintileHighest quintileDelivery of evidence-based careLower household incomeMonthsEvidence-based careCopayment amountQuintileAdultsReduce financial barriersDiscontinuationEducation levelIdentified factorsCharacterizing Long COVID Symptoms During Early Childhood
Gross R, Thaweethai T, Salisbury A, Kleinman L, Mohandas S, Rhee K, Snowden J, Tantisira K, Warburton D, Wood J, Kinser P, Milner J, Rosenzweig E, Irby K, Flaherman V, Karlson E, Chibnik L, Pant D, Krishnamoorthy A, Gallagher R, Lamendola-Essel M, Hasson D, Katz S, Yin S, Dreyer B, Blancero F, Carmilani M, Coombs K, Fitzgerald M, Letts R, Peddie A, Foulkes A, Stockwell M, Darden P, Dixon L, Evans D, Garbe C, Hobart-Porter L, Howard L, Hummel K, Krehbiel H, Spradlin H, Yount P, Adam G, Angal J, Barber M, Clark K, Dos Reis C, Freesemann M, Friedrich C, Hockett C, Johannsen R, Johnson-Vonk E, Kaiser C, Kruse A, Lang J, Lim P, McCoy M, Miller L, Petereit (Cerkovnik) S, RiChard (Werpy) J, Seiler J, Sundleaf B, Svendsen J, Trosper B, Vermeulen O, Young S, Dabney S, Fahrner M, Gallagher T, Martini K, McNally M, Vivensi Stiverson S, Balaraman V, Cheung J, Hong T, Kalua S, Minami E, Siu A, Tong M, Dantas M, Kasmarcak T, Milks K, Ikomi C, Meyer M, Nguyen C, Pellicciotti G, Phan T, Ravin K, Reynolds V, Strang A, Thacker D, Eckrich D, Goetter A, Katz C, Kowal K, McDevitt C, Agosto Roman G, Alshawabkeh A, Ayala Ortiz I, Casey V, Cordero J, De Jesus J, Galan Rivera C, Huerta-Montanez G, Otero N, Rivera Robles M, Roman P, Roman G, Rosario-Pabon Z, Santiago X, Velez-Vega C, Vergara C, Albarado B, Allen T, Attuso A, Ayers T, Bebler E, Bella G, Bennett A, Brown J, Carville A, Darby S, Devall K, Dragg A, Elderedge A, Fontenot E, Fry G, Gildersleeve B, Goff S, Harrington L, Jones L, Kaiser V, Lee Y, Lee S, LeJeune E, Leonhard R, Levatino J, Lewis D, Lloyd A, Monce R, Munro S, Phillips M, Pucheu B, Rachal E, Rood J, Roussel S, Rumsey R, Sanford C, Santos M, Stafford A, Thomassie A, Waguespack C, Walgamotte K, Welch M, Windham A, Bell T, Boyd J, Dasgupta S, Deans S, Harris K, Hemmerle M, King S, McGuire C, Merten B, Morris S, Ray M, Reinhardt B, Shemwell S, Simeon T, Walker K, Watson S, Weakley K, Figliomeni J, Fischer L, Hoover D, Morse M, Nabower A, Roberts E, Sato A, Von Bon J, Archuleta D, Brito R, Campbell R, Chavez J, Dehority W, Garcia-Soberanez N, Gronert E, Kadish M, Larrabee J, Lovato D, Luo K, Martinez N, Merlino A, Reese E, Ward S, Wilson K, Brown R, Butchee R, Fergeson G, McKee R, Mohler B, Moore T, Owens V, Stubbs S, VanWagoner T, Bethel M, Chassereau L, Lahiri T, Lake L, Moffett K, Polak E, Stutler S, Workman C, Carpenter E, Dhindsa I, Mejia S, Moghadam N, Mulder C, O'Neil S, Osornio A, Rios A, Rosen S, Smith A, Tabibi D, Tang S, Teame A, Stockwell M, Anderson B, Aquino T, Berg E, Caddle S, Catallozzi M, Chung W, Connors T, De A, Diaz Perez A, DiLorenzo M, Dumitriu D, Farooqi K, Fremed M, Goldman S, Kaplan K, Krishnan U, Layton A, Lignelli-Dipple A, McClaren S, Overdevest J, Rodriguez M, Selman J, Silver W, Silverio R, Valdez de Romero A, Vargas C, Caputo D, Leggieri C, Pretsch P, Davis K, Griffith M, Harris D, Macario E, Steffes J, Torres A, Day C, Howell K, Mains M, Bean E, DeFelice C, El Chebib H, Herbst K, Lesmes S, Santos M, Schulman N, Brooks-Greien A, Colin K, Juarez-Colunga A, Manning B, Shields J, York D, Griswold J, Lee D, Nowakowski A, Riordan M, Aamir R, Abuzahrieh M, Bangalore N, Brown A, Dalton W, Fortuna S, Minium J, Rosolowski B, Ahmed A, Braniecki S, Contreras M, Jain S, Kaseta S, Messer Z, Ramirez A, Singh A, WIlliams R, Akerlundh A, Akshoomoff N, Arroyo M, Barrientos W, Bhattacharjee R, Chao B, Diaz M, Garcia S, Garcia S, Gomez G, Herrera T, Holguin M, Khare M, Kiernan E, Landeo Gutierrez J, Matta I, Reyes S, Ryu J, Sanchez C, Schreck A, Warner M, Cerracchio L, Folnagy A, Gzemski S, Hao Y, Li S, Moroso S, Ness-Cochinwala M, Patel A, Richlin B, Sharma H, Soto D, Suarez C, Vargas Forero B, Ricciardi E, Trespalacios V, Kluko M, Rhee K, Tantisira K, Acosta Valle D, Chao B, Choudhary A, Glenn-Arroyo M, Kiernan E, Landeo-Gutierrez J, Madan A, McConnaughey K, Ramos Vallejo L, Sanchez C, Suarez M, Caldas S, Castro Ovalle T, Chung A, Farkas J, Isidoro-Chino M, Kesebir D, Kim E, Quarless A, Schlechter A, Srinivasan R, Barry F, Burton P, Cano Lorente R, Cummins C, Wehbe S, Espinoza J, Moyer S, Rider A, Russell S, Schecter M, Stevenson L, Burns J, Spudich S, Bailey C, Cicek M, Cortez M, Davis Blakley F, Goff D, Lasky-Su J, Newman L, Ofotokun I, Seshadri S, Stone J, Taylor B, Utz P, Williams N, Abella J, Barnette Q, Bevc C, Beverly J, Ceger P, Croxford J, Cunningham E, Enger M, Fain K, Farris T, Hanlon S, Hines D, Johnson-Lawrence V, Jordan K, Lefebvre C, Linas B, Luukinen B, Mandal M, McKoy N, Nance S, Oakland A, Pasquarelli D, Quiner C, Sembajwe R, Shaw G, Thornburg V, Tosco K, Wright H, Hochman J, Horwitz L, Katz S, Troxel A, Adler L, Akinbo P, Almenana R, Bello O, Bhuiyan S, Blachman N, Branski R, Briscoe J, Brosnahan S, Bueler E, Burgos Y, Caplin N, Chaplin D, Chen Y, Cheng S, Choe P, Choi J, Chung A, Church R, Cobos S, Croft N, Cruz Irving A, Del Boccio P, Díaz I, Doshi V, Ebel S, Faustin A, Febres E, Fine J, Fink S, Frontera J, Gonzalez-Duarte A, Hill S, Islam S, Johnson S, Kansal N, Kenney R, Kewlani D, Laynor G, Leon T, Lewczak Z, Linton J, Logan M, Malik N, Mamistvalova L, Mandel H, Maranga G, Mathews P, Mattoo A, Mei T, Mendelsohn A, Mercier E, Millar Vernetti P, Miller M, Mitchell M, Moreira A, Mudumbi P, Nahin E, Nair N, Nekulak J, Owens K, Parent B, Patibandla N, Petrov P, Postelnicu R, Randall I, Rao P, Rapkiewicz A, Rizzo J, Rosas J, Rose C, Saint-Jean C, Santacatterina M, Shah B, Shaukat A, Simon N, Simsir A, Stinson M, Tang W, Tatapudi V, Thawani S, Thomas M, Thorpe L, Tom M, Treiha E, Truong J, Udosen M, Velazquez-Perez J, Vernetti P, Vidal C, Viswanathan A, Wong C, Wood M, Wuller S, Young C, Zaretsky J, Zavlunova S, Foulkes A, Murphy S, Ahirwar S, Ainsworth L, Ajani S, Alsheikh A, Atchley-Challenner R, Avilach P, Balan T, Benik N, Benoit B, Bonaventura W, Boutin N, Brion B, Cagan A, Cai T, Cao T, Castro V, Cerretani X, Ciriello M, Costenbader K, Dimitrov D, Estiri H, Fang M, Fayad M, Feldman C, Gainer V, Ghosh B, Gollub R, Harris A, Helmer K, Hendrix A, Holzbach A, Huang W, Kaufman D, Keogh D, Kerr J, Klann J, Lasky-Su J, Liao K, MacFadden D, Maram A, Martel M, Mendis M, Metta R, Monteiro J, Morales E, Nazaire M, Neils G, Norman J, Paik H, Park H, Qian Z, Rossi-Roh K, Santacroce L, Selvaggi C, Simons W, Simpson L, Strasser Z, Tariq A, Thorn M, Trewett P, Van Fleet D, Wagholikar K, Wang H, Wang T, Wattanasin N, Weber G, Williams M, Flotte T, Boysen E, Chang N, Ellingworth E, Frisch E, Welch G, Yusuf A, Zahnle N, Cerda M, Clash V, Taylor B, Zissis M, Akintonwa T, Brown H, Copeland D, Hall Y, kondo K, Lerma L, Lindsay J, Marti H, Maughan C, Minor T, Vincent H, Blomkalns A, Bassett I, Clifton R, Davis H, Erdmann N, Gage Witvliet M, Goldberg M, Guan Z, Jain M, Klein J, Martinez T, McGrath R, Parthasarathy S, Pemu P, Rutter J, Aschner J, Atz A, Banerjee D, Bogie A, Bukulmez H, Clouser K, Cottrell L, Cowan K, D’Sa V, Dozor A, Elliott A, Faustino E, Fiks A, Gaur S, Gennaro M, Gordon S, Hasan U, Hester C, Hogan A, Hsia D, Kaelber D, Kosut J, Krishnan S, McCulloh R, Michelow I, Nolan S, Oliveira C, Olson L, Pace W, Palumbo P, Raissy H, Reyes A, Ross J, Salazar J, Selvarangan R, Stein C, Stevenson M, Teufel R, Werzberger A, Westfall J, Zani K, Zempsky W, Zimmerman E, Bind M, Chan J, Guan Z, Morse R, Reeder H, Metz T, Newburger J, Truong D. Characterizing Long COVID Symptoms During Early Childhood. JAMA Pediatrics 2025, 179: 781-792. PMID: 40554463, PMCID: PMC12117493, DOI: 10.1001/jamapediatrics.2025.1066.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPreschool-aged childrenAge groupsCohort studyLong COVIDHistory of SARS-CoV-2 infectionPoorer overall healthUS health careLongitudinal cohort studySARS-CoV-2 infectionDry coughCommunity settingsHealth careMain OutcomesSymptom SurveyInfection historyLong COVID symptomsOverall healthVulnerable populationsPerceived delayEarly childhoodProlonged symptomsHigher scoresOlder ageInfants/toddlersStudy data
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