Jeremy Liu, MD
Hospital ResidentCards
About
Research
Publications
2026
Novel Clinical Trial Designs for Intermediate Age-Related Macular Degeneration
Berni A, Shen M, Liu J, Kastner J, El-Mulki O, Beqiri S, Herrera G, Trivizki O, Waheed N, Usner D, Levy B, O’Brien R, Gregori G, Rosenfeld P. Novel Clinical Trial Designs for Intermediate Age-Related Macular Degeneration. Ophthalmology Science 2026, 6: 101179. PMID: 42211726, PMCID: PMC13213873, DOI: 10.1016/j.xops.2026.101179.Peer-Reviewed Original Research
2025
Real-World Experience With Intravitreal Pegcetacoplan for the Treatment of Geographic Atrophy in Age-Related Macular Degeneration
Shen M, Berni A, Liu J, Hiya F, Herrera G, El-Mulki O, Beqiri S, Cheng Y, Kastner J, Trivizki O, Kumar S, Zhang Y, Le V, O'Brien R, Nicola M, Yehoshua Z, Dubovy S, Wang R, Gregori G, Rosenfeld P. Real-World Experience With Intravitreal Pegcetacoplan for the Treatment of Geographic Atrophy in Age-Related Macular Degeneration. American Journal Of Ophthalmology 2025, 281: 31-41. PMID: 40915520, DOI: 10.1016/j.ajo.2025.09.006.Peer-Reviewed Original ResearchHyperreflective Foci Along the Retinal Pigment Epithelium Predict the Onset of Large Choroidal Hypertransmission Defects in Age-Related Macular Degeneration
Berni A, Kastner J, Shen M, Cheng Y, Herrera G, Hiya F, Liu J, Wang L, Li J, El-Mulki O, Beqiri S, Trivizki O, Waheed N, O’Brien R, Gregori G, Wang R, Rosenfeld P. Hyperreflective Foci Along the Retinal Pigment Epithelium Predict the Onset of Large Choroidal Hypertransmission Defects in Age-Related Macular Degeneration. American Journal Of Ophthalmology 2025, 274: 76-90. PMID: 39987980, PMCID: PMC12492339, DOI: 10.1016/j.ajo.2025.02.021.Peer-Reviewed Original ResearchDeterminants of Four-Year Visual Acuity Loss in Geographic Atrophy An Analysis of Age-Related Eye Disease Study and Age-Related Eye Disease Study 2
Shen L, Kaiser P, Liu J, Stewart J, Heyang M, Keenan T, Sunness J, Rosenfeld P, Chew E, Del Priore L. Determinants of Four-Year Visual Acuity Loss in Geographic Atrophy An Analysis of Age-Related Eye Disease Study and Age-Related Eye Disease Study 2. Ophthalmology 2025, 132: 785-798. PMID: 39921001, DOI: 10.1016/j.ophtha.2025.01.028.Peer-Reviewed Original Researchbaseline best-corrected visual acuitybest-corrected visual acuitybest-corrected visual acuity changebest-corrected visual acuity lossage-related eye disease studygeographic atrophyfoveal centerBCVA lossvisual acuityGA progressionGA secondary to nonexudative age-related macular degenerationbest-corrected visual acuity datanonexudative age-related macular degenerationminimum angle of resolutionage-related macular degenerationangle of resolutionvisual acuity lossEye Disease Studycolor fundus photographsbaseline to year 1randomized controlled clinical trialGA growth ratecontrolled clinical trialsmultivariable linear mixed-effects modelsAREDS2 participantsTractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography.
Rohowetz L, Iyer P, Ashkenazy N, Fan K, Laiginhas R, Shi Y, Liu J, Rosenfeld P, Flynn H. Tractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography. Ophthalmic Surgery Lasers And Imaging Retina 2025, 56: 244-248. PMID: 39840953, DOI: 10.3928/23258160-20241101-04.Peer-Reviewed Original Research
2024
Comparison between Spectral-domain and Swept-source OCT Angiography Scans for the Measurement of Hyperreflective Foci in Age-related Macular Degeneration
Herrera G, Cheng Y, Attiku Y, Hiya F, Shen M, Liu J, Lu J, Berni A, Trivizki O, Li J, O’Brien R, Gregori G, Wang R, Rosenfeld P. Comparison between Spectral-domain and Swept-source OCT Angiography Scans for the Measurement of Hyperreflective Foci in Age-related Macular Degeneration. Ophthalmology Science 2024, 5: 100633. PMID: 39758131, PMCID: PMC11699460, DOI: 10.1016/j.xops.2024.100633.Peer-Reviewed Original Researchage-related macular degenerationretinal pigment epitheliumSS-OCTAmacular degenerationOCT angiographyangiography scansswept-source OCT angiographysemiautomated algorithmB-scanscommercial disclosureneurosensory retinaBruch's membranepigment epitheliumspectral-domainLin's concordance correlation coefficientimaging modalitiesEvaluating the persistence of large choroidal hypertransmission defects using SS-OCT imaging
Beqiri S, Herrera G, Liu J, Shen M, Berni A, El-Mulki O, Cheng Y, Trivizki O, Kastner J, O’Brien R, Gregori G, Wang R, Rosenfeld P. Evaluating the persistence of large choroidal hypertransmission defects using SS-OCT imaging. Experimental Eye Research 2024, 248: 110117. PMID: 39368694, PMCID: PMC11532011, DOI: 10.1016/j.exer.2024.110117.Peer-Reviewed Original ResearchConceptsage-related macular degenerationretinal pigment epitheliumatrophic age-related macular degenerationoptical coherence tomographyhyperreflective materialpigment epitheliumSS-OCTswept-source OCTnatural history studiesslow disease progressionclinical trial endpointsAMD eyesRPE cellsmacular degenerationcoherence tomographychoroidfocal attenuationdisease progressiontrial endpointsComparison between Spectral-Domain and Swept-Source OCT Angiography for the Measurement of Persistent Hypertransmission Defects in Age-Related Macular Degeneration
Herrera G, Shen M, Trivizki O, Liu J, Shi Y, Hiya F, Li J, Cheng Y, Lu J, Zhang Q, O’Brien R, Gregori G, Wang R, Rosenfeld P. Comparison between Spectral-Domain and Swept-Source OCT Angiography for the Measurement of Persistent Hypertransmission Defects in Age-Related Macular Degeneration. Ophthalmology Science 2024, 5: 100593. PMID: 39318709, PMCID: PMC11417529, DOI: 10.1016/j.xops.2024.100593.Peer-Reviewed Original Researchage-related macular degenerationswept-source OCT angiographySS-OCTAOCT angiographymacular degenerationlate-stage age-related macular degenerationnonexudative age-related macular degenerationdetection of atrophycommercial disclosureBruch's membranespectral-domainpairs of scansangiographysemiautomated algorithmoutcome measurespatientslesionsdegenerationLongitudinal SS-OCT choroidal imaging following thrombosis of the superior ophthalmic vein
Shen M, Iyer P, Zhou H, Cheng Y, Liu J, Trivizki O, Wang R, Gregori G, Rosenfeld P. Longitudinal SS-OCT choroidal imaging following thrombosis of the superior ophthalmic vein. American Journal Of Ophthalmology Case Reports 2024, 36: 102130. PMID: 39156907, PMCID: PMC11328022, DOI: 10.1016/j.ajoc.2024.102130.Peer-Reviewed Original ResearchThe Total Macular Burden of Hyperreflective Foci and the Onset of Persistent Choroidal Hypertransmission Defects in Intermediate AMD
Berni A, Shen M, Cheng Y, Herrera G, Hiya F, Liu J, Wang L, Li J, Zhou S, Trivizki O, Waheed N, O’Brien R, Gregori G, Wang R, Rosenfeld P. The Total Macular Burden of Hyperreflective Foci and the Onset of Persistent Choroidal Hypertransmission Defects in Intermediate AMD. American Journal Of Ophthalmology 2024, 267: 61-75. PMID: 38944135, PMCID: PMC11486582, DOI: 10.1016/j.ajo.2024.06.023.Peer-Reviewed Original ResearchConceptsSS-OCT angiographyarea under the curveSS-OCTretrospective reviewdisease progressionmedian follow-up timepredictors of disease progressionswept-source optical coherence tomographypost hoc subgroup analysisunivariate Cox regression analysisfollow-up timeCox regression analysisfollow-up visitoptical coherence tomographyBruch's membranepigment epitheliumprospective studycoherence tomography