Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsJames Samuel, MD
Assistant Clinical ProfessorAbout
Research
Publications
2026
Subverting Host Defense from Within: Innate Immune Modulation by Coxiella burnetii
Busbee A, Arunima A, Samuel J, van Schaik E. Subverting Host Defense from Within: Innate Immune Modulation by Coxiella burnetii. Pathogens 2026, 15: 444. PMID: 42075771, PMCID: PMC13119068, DOI: 10.3390/pathogens15040444.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2025
CYP1B1-AS1 regulates CYP1B1 to promote Coxiella burnetii pathogenesis by inhibiting ROS and host cell death
Arunima A, Niyakan S, Butler S, Clark S, Pinson A, Kwak D, Case E, Qian X, de Figueiredo P, van Schaik E, Samuel J. CYP1B1-AS1 regulates CYP1B1 to promote Coxiella burnetii pathogenesis by inhibiting ROS and host cell death. Nature Communications 2025, 16: 7493. PMID: 40796858, PMCID: PMC12344041, DOI: 10.1038/s41467-025-62762-2.Peer-Reviewed Original ResearchMicrofluidic droplets with amended culture media cultivate a greater diversity of soil microorganisms
Dai J, Ouyang Y, Gupte R, Liu X, Li Y, Yang F, Chen S, Provin T, Van Schaik E, Samuel J, Jayaraman A, Zhou A, de Figueiredo P, Zhou J, Han A. Microfluidic droplets with amended culture media cultivate a greater diversity of soil microorganisms. Applied And Environmental Microbiology 2025, 91: e01794-24. PMID: 39936906, PMCID: PMC11921321, DOI: 10.1128/aem.01794-24.Peer-Reviewed Original Research
2024
μREACT: A microfluidic system for rapid evaluation of trans-kingdom interactions
Huang C, Yang J, Chen S, Han S, Zhang H, Samuel J, Van Schaik E, de Figueiredo P, Han A. μREACT: A microfluidic system for rapid evaluation of trans-kingdom interactions. Biosensors And Bioelectronics 2024, 267: 116838. PMID: 39393191, DOI: 10.1016/j.bios.2024.116838.Peer-Reviewed Original ResearchMolecular mechanisms of Coxiella burnetii formalin-fixed cellular vaccine reactogenicity
Fratzke A, Szule J, Butler S, Schaik E, Samuel J. Molecular mechanisms of Coxiella burnetii formalin-fixed cellular vaccine reactogenicity. Infection And Immunity 2024, 92: e00335-24. PMID: 39356158, PMCID: PMC11556133, DOI: 10.1128/iai.00335-24.Peer-Reviewed Original ResearchVaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria
van Schaik E, Fratzke A, Gregory A, Dumaine J, Samuel J. Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria. Frontiers In Cellular And Infection Microbiology 2024, 14: 1282183. PMID: 38567021, PMCID: PMC10985213, DOI: 10.3389/fcimb.2024.1282183.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1992
An experimental model for subclinical edema disease (Escherichia coli enterotoxemia) manifest as vascular necrosis in pigs.
Kausche F, Dean E, Arp L, Samuel J, Moon H. An experimental model for subclinical edema disease (Escherichia coli enterotoxemia) manifest as vascular necrosis in pigs. American Journal Of Veterinary Research 1992, 53: 281-7. PMID: 1595951, DOI: 10.2460/ajvr.1992.53.3.281.Peer-Reviewed Original Research