Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsIsrael Franco, MD, FAAP, FACS
Professor Adjunct of Clinical UrologyAbout
Research
Publications
2025
Neuropsychiatric Disorders and their Association with Lower Urinary Tract Symptoms in Children
Franco I. Neuropsychiatric Disorders and their Association with Lower Urinary Tract Symptoms in Children. Current Treatment Options In Pediatrics 2025, 11: 35. DOI: 10.1007/s40746-025-00349-1.Peer-Reviewed Original ResearchAnterior cingulate cortexAttention-deficit/hyperactivity disorderNorepinephrine reuptake inhibitorsReuptake inhibitorsPrefrontal cortexEarly life stressSerotonin reuptake inhibitorsLower urinary tract symptomsFrontal lobe activityCentral neurotransmitter systemsDefault mode networkNeurobiological underpinningsExecutive functionCingulate cortexAttention-deficit/hyperactivityLife stressMode networkNeurotransmitter systemsNeuroanatomical basisNeuropsychiatric conditionsNeuropsychiatric disordersElimination disordersRight frontal lobeBrain regionsNeurodevelopmental vulnerabilityResponse to Commentary on "Are Rhythmic Bladder Contractions Affected by Fill Rate and Bladder Work in Neurogenic Bladders"
Franco I. Response to Commentary on "Are Rhythmic Bladder Contractions Affected by Fill Rate and Bladder Work in Neurogenic Bladders". Journal Of Pediatric Urology 2025 PMID: 41372051, DOI: 10.1016/j.jpurol.2025.11.005.Peer-Reviewed Original ResearchUroflowmetry: An Alternative View Using a Quantitative Approach
Franco I. Uroflowmetry: An Alternative View Using a Quantitative Approach. 2025, 41-56. DOI: 10.1007/978-981-95-2709-0_6.Peer-Reviewed Original ResearchAre Rhythmic Bladder Contractions Affected by Fill Rate and Bladder Work in Neurogenic Bladders.
Cullingsworth Z, Goodman R, Farhat W, Franco I. Are Rhythmic Bladder Contractions Affected by Fill Rate and Bladder Work in Neurogenic Bladders. Journal Of Pediatric Urology 2025 PMID: 41206264, DOI: 10.1016/j.jpurol.2025.10.008.Peer-Reviewed Original ResearchRhythmic bladder contractionsUrodynamic studiesNeurogenic bladderBladder contractionsNB patientsBladder filling rateReceiver Operating Characteristic (ROC) analysisBland-Altman analysisBladder hypertrophyUrodynamic parametersBladderROC analysisAltman analysisRhythmic activityFilling rateMotion artifactsClinical thresholdAmplitude cutoffPatientsDetrusorStatistical evaluationIntrinsic activityHypertrophyUtilization of the modified Bosniak classification system for complex renal cysts
Frumer M, Ben-Meir D, Shenhar C, Peard L, Buchanan A, Hittelman A, Franco I. Utilization of the modified Bosniak classification system for complex renal cysts. Pediatric Nephrology 2025, 40: 3637-3645. PMID: 40504241, DOI: 10.1007/s00467-025-06848-5.Peer-Reviewed Original ResearchPD14-06 IS THERE A CORRELATION BETWEEN BUCCAL MUCOSAL GRAFT WIDTH AND LENGTH AND UROFLOW CHARACTERISTICS?
Patel S, Franco I, Mathew C, Mendelson J, Friedman S, Fine R, Horowitz M, Schlussel R, Landau-Dyer L, Zelkovic P, Freyle J, Gitlin J. PD14-06 IS THERE A CORRELATION BETWEEN BUCCAL MUCOSAL GRAFT WIDTH AND LENGTH AND UROFLOW CHARACTERISTICS? Journal Of Urology 2025, 213: e515. DOI: 10.1097/01.ju.0001109884.89796.13.06.Peer-Reviewed Original ResearchPredicting Elevated Postvoid Residual Urine Volume Following OnabotulinumtoxinA Treatment for Overactive Bladder: A Pilot Study
Franco I, Schwartz M, Cline K, Glazier D, Patel A. Predicting Elevated Postvoid Residual Urine Volume Following OnabotulinumtoxinA Treatment for Overactive Bladder: A Pilot Study. LUTS Lower Urinary Tract Symptoms 2025, 17: e70004. PMID: 39800349, PMCID: PMC11725389, DOI: 10.1111/luts.70004.Peer-Reviewed Original ResearchConceptsOveractive bladderUrine flow rateOnabotulinumtoxinA treatmentPatient ageElevated postvoid residual urine volumeElevated postvoid residual volumePostvoid residual urine volumePeak urine flow rateSymptoms of overactive bladderAverage urine flow ratePostvoid residual volumeIdiopathic overactive bladderResidual urine volumeOveractive bladder treatmentEvaluate potential predictorsLogistic regression analysisMedical chart dataOnabotulinumtoxinA administrationIndex therapyUrinary urgencyRetrospective reviewUrine volumeUrology clinicPVR valuesUrinary condition
2024
Erectile Dysfunction in Adolescents and Young Adults
Pantazis A, Franco I, Gitlin J. Erectile Dysfunction in Adolescents and Young Adults. Current Urology Reports 2024, 25: 225-232. PMID: 38922362, DOI: 10.1007/s11934-024-01213-9.Peer-Reviewed Original ResearchConceptsPsychogenic etiologyCognitive behavioral therapyYoung adultsErectile dysfunctionBehavioral therapyPornography consumptionCortisol levelsAdolescent malesNormal testosterone levelsPediatric urology practiceAnxietyDepressionOnline pornography consumptionFindingsThe latest researchAdolescentsPediatric urologistsVascular resistanceUrological practiceTreatment recommendationsTestosterone levelsWork-upReviewThe goalDysfunctionAdultsErectileManagement of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine
Shain S, Gitlin J, Pantazis A, Fine R, Horowitz M, Friedman S, Zelkovic P, Dyer L, Schlussel R, Freyle J, Fang A, Sommer J, Franco I. Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine. Journal Of Pediatric Urology 2024, 20: 603.e1-603.e8. PMID: 38871547, DOI: 10.1016/j.jpurol.2024.05.024.Peer-Reviewed Original ResearchVancouver Symptom ScoreInternational Children's Continence SocietyWet nightsDesmopressin treatmentCombination therapyResponse rateIntent-to-treat response rateCombination therapy of desmopressinFirst-line medical therapyEfficacy of adjunctive therapyGroup IMPComplete response rateTreated with desmopressinCohort of patientsContinence successPrescribed desmopressinEnuresis patientsMedical therapyNighttime drynessChart reviewAdjunctive therapyConclusion A combinationDesmopressinOxybutyninPediatric populationSize matters: Total testicular volume predicts sperm count in Tanner V varicocele patients
Fang A, Franco I, Pizzuti J, Boroda J, Friedman S, Fine R, Horowitz M, Schlussel R, Landau-Dyer L, Zelkovic P, Freyle J, Sommer J, Gitlin J. Size matters: Total testicular volume predicts sperm count in Tanner V varicocele patients. Journal Of Pediatric Urology 2024, 20: 960-966. PMID: 38876892, DOI: 10.1016/j.jpurol.2024.05.012.Peer-Reviewed Original ResearchNegative predictive valueSemen analysisAbnormal SAPredictive valueSperm countSurgical interventionTesticular volumeRetrospective single-center chart reviewSingle-center chart reviewOdds ratioAppropriateness of surgical interventionLeft-sided varicoceleMotile sperm countAbnormal semen analysisReceiver operating characteristic analysisPrevalence of varicoceleMultivariate logistic regressionTotal testicular volumeYouden's J statisticVaricocele gradeMedian ageChart reviewUltrasound resultsYounger patientsRisk stratification
Academic Achievements & Community Involvement
News
News
- July 28, 2023
Yale Urology Research [Q2: April-June 2023]
- June 12, 2023Source: Physician's Weekly / Journal of Pediatric Urology
Is It Time To Reconsider How We Document Pediatric Uroflow Studies?
- May 03, 2023
17 Yale Urology Affiliated Physicians Named “Top Doctors” for 2023
- April 20, 2023
Yale Urology Research [Q1: January-March 2023]