A Bayesian approach to correcting the attenuation bias of regression using polygenic risk score
Zhou G, Qie X, Zhao H. A Bayesian approach to correcting the attenuation bias of regression using polygenic risk score. Genetics 2025, 229: iyaf018. PMID: 39891671, PMCID: PMC12168083, DOI: 10.1093/genetics/iyaf018.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresRisk scoreEstimation of regression coefficientsBayesian approachMeasurement error modelEstimation of coefficientsCoverage probabilityBayesian measurement error modelsAttenuation biasCredible intervalsCoefficient estimatesUK BiobankLogistic regressionMeasurement errorRegression coefficientsRegression modelsComplex traitsRegression analysisScoresEstimationError modelRegressionBiobankErrorCovariates
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