About
Titles
Research Associate Psychiatry
Research
Research at a Glance
Publications Timeline
A big-picture view of Hayde Sanchez's research output by year.
8Publications
462Citations
Publications
2016
The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory
Monsey MS, Sanchez H, Taylor JR. The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory. Neuropsychopharmacology 2016, 42: 587-597. PMID: 27380937, PMCID: PMC5240167, DOI: 10.1038/npp.2016.117.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCocaine-cue memoriesCocaine self-administration trainingLight/tone cuesCue-induced cocaine-seeking behaviorCocaine-Associated MemorySelf-administration trainingCocaine-seeking behaviorActive lever pressesCue memoryInfusion of cocaineLever extinctionReconsolidation processTone cuesSuch cuesDrug takingMemoryLever pressesCuesReconsolidationNew responsesAbstinenceDrug abuseEnvironmental stimuliCocaine useCocaine access
2014
Activation of Exchange Protein Activated by cAMP in the Rat Basolateral Amygdala Impairs Reconsolidation of a Memory Associated with Self-Administered Cocaine
Wan X, Torregrossa MM, Sanchez H, Nairn AC, Taylor JR. Activation of Exchange Protein Activated by cAMP in the Rat Basolateral Amygdala Impairs Reconsolidation of a Memory Associated with Self-Administered Cocaine. PLOS ONE 2014, 9: e107359. PMID: 25259911, PMCID: PMC4178027, DOI: 10.1371/journal.pone.0107359.Peer-Reviewed Original ResearchCitationsAltmetric
2010
d-Cycloserine Reduces the Context Specificity of Pavlovian Extinction of Cocaine Cues through Actions in the Nucleus Accumbens
Torregrossa MM, Sanchez H, Taylor JR. d-Cycloserine Reduces the Context Specificity of Pavlovian Extinction of Cocaine Cues through Actions in the Nucleus Accumbens. Journal Of Neuroscience 2010, 30: 10526-10533. PMID: 20685995, PMCID: PMC2918879, DOI: 10.1523/jneurosci.2523-10.2010.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCue-induced reinstatementD-cycloserineNovel contextExtinction learningExtinction therapyContext specificityExtinction sessionsBrief memory reactivation sessionAdministration of DCSMemory reactivation sessionCue exposure therapyCue-induced relapseDrug-associated cuesDrug-taking contextCocaine-associated cuesAbsence of extinctionNeurobiology of addictionSelf-administer cocainePrelimbic prefrontal cortexReactivation sessionContext AContext BPavlovian extinctionExposure therapyMotivational impactReconsolidation of a Cocaine-Associated Stimulus Requires Amygdalar Protein Kinase A
Sanchez H, Quinn JJ, Torregrossa MM, Taylor JR. Reconsolidation of a Cocaine-Associated Stimulus Requires Amygdalar Protein Kinase A. Journal Of Neuroscience 2010, 30: 4401-4407. PMID: 20335476, PMCID: PMC2881637, DOI: 10.1523/jneurosci.3149-09.2010.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAmygdalaAnalysis of VarianceAnimalsAssociation LearningCocaineConditioning, OperantCuesCyclic AMPCyclic AMP-Dependent Protein KinasesDopamine Uptake InhibitorsExploratory BehaviorExtinction, PsychologicalMaleProtein Kinase InhibitorsRatsRats, Sprague-DawleyReinforcement, PsychologySelf AdministrationThionucleotidesConceptsSubsequent cue-induced reinstatementCocaine-paired stimulusCue-induced reinstatementLight/tone stimulusIntra-amygdalar infusionLight/toneDrug-paired stimuliNew instrumental responseDrug-associated stimuliIntravenous cocaine infusionsCocaine-induced reinstatementLever extinctionMemory reconsolidationStimulus memoryMemory restabilizationReinstatement testingBehavioral treatmentPKA inhibitor Rp-cAMPSAddictive disordersTone stimuliReconsolidationInstrumental responseCocaine infusionsDrug addictionReinstatement
2007
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine
Taylor JR, Lynch WJ, Sanchez H, Olausson P, Nestler EJ, Bibb JA. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 4147-4152. PMID: 17360491, PMCID: PMC1820723, DOI: 10.1073/pnas.0610288104.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsNucleus accumbensInhibition of Cdk5Progressive ratio scheduleStriatal dopamineLocomotor sensitizationCocaine exposureIncentive motivational effectsCocaine-induced locomotor sensitizationChronic cocaine exposureSaline-injected ratsSubsequent cocaine challengeRatio scheduleTranscription factor DeltaFosBCdk5 inhibitor roscovitineCyclin-dependent kinase 5Intra-NAc infusionsLong-term adaptationNAC infusionStriatal neuronsCocaine challengeCocaine injectionStimulant actionCocaine sensitizationLocomotor responseInfusion
2005
Neonatal isolation alters the estrous cycle interactions on the acute behavioral effects of cocaine
Kosten T, Sanchez H, Jatlow P, Kehoe P. Neonatal isolation alters the estrous cycle interactions on the acute behavioral effects of cocaine. Psychoneuroendocrinology 2005, 30: 753-761. PMID: 15919581, DOI: 10.1016/j.psyneuen.2005.03.004.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsEstrous stageNeonatal isolationBehavioral effectsNH femalesCocaine dosesNon-handled conditionsLow cocaine dosesCocaine plasma levelsEffects of estrogenVentral striatal dopamineAcute behavioral effectsAbility of cocaineHigher cocaine dosesAcquisition of cocaineAcute behavioral responsesMonoamine levelsStriatal dopamineSerotonin levelsPlasma levelsEstrous cyclicityFemale ratsISO ratsIsolation altersDiestrus stageEstrus rats
2004
Neonatal isolation enhances maintenance but not reinstatement of cocaine self-administration in adult male rats
Zhang X, Sanchez H, Kehoe P, Kosten T. Neonatal isolation enhances maintenance but not reinstatement of cocaine self-administration in adult male rats. Psychopharmacology 2004, 177: 391-399. PMID: 15258719, DOI: 10.1007/s00213-004-1963-y.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsAdult male ratsNeonatal isolationMale ratsCocaine-induced reinstatementPR scheduleCocaine dosesExtinguished self-administration behaviorLow cocaine dosesProgressive ratioEarly life stressNon-handled ratsSelf-administration behaviorAcquisition of cocaineDifferent cocaine dosesCocaine-seeking behaviorSelf-administer cocaineReinstatement of cocaineLow dosesRatsCocaineMore cocaineDosesLife stressGroup differencesSeparate groupsNeonatal isolation enhances acquisition of cocaine self-administration and food responding in female rats
Kosten T, Sanchez H, Zhang X, Kehoe P. Neonatal isolation enhances acquisition of cocaine self-administration and food responding in female rats. Behavioural Brain Research 2004, 151: 137-149. PMID: 15084429, DOI: 10.1016/j.bbr.2003.08.010.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAnalysis of VarianceAnimalsAnimals, NewbornBehavior, AddictiveBody WeightCocaineConditioning, OperantDopamine Uptake InhibitorsDose-Response Relationship, DrugFeeding BehaviorFemaleMaleMotor ActivityRatsRats, Sprague-DawleyReinforcement ScheduleReinforcement, PsychologySelf AdministrationSex FactorsSocial Isolation