About
Research
Publications
2026
Fly navigational responses exploit plume-specific odor motion and gradient cues
Brudner S, Zhou B, Jayaram V, Santana G, Crimaldi J, Clark D, Emonet T. Fly navigational responses exploit plume-specific odor motion and gradient cues. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2608896123. PMID: 42446985, PMCID: PMC13389596, DOI: 10.1073/pnas.2608896123.Peer-Reviewed Original Research
2025
Visual circuitry for distance estimation in Drosophila
Shomar J, Wu E, Au B, Maier K, Zhou B, Matos N, Sager G, Santana G, Tanaka R, Gish C, Clark D. Visual circuitry for distance estimation in Drosophila. Current Biology 2025, 35: 5136-5149.e8. PMID: 41015039, PMCID: PMC12652897, DOI: 10.1016/j.cub.2025.09.008.Peer-Reviewed Original ResearchConceptsmotion parallaxdistance estimationfeature-detecting neuronstwo-dimensional retinal imagesneural signalsDrosophila visual systemhigh-throughput behavioral assaybackground motionvisual distancefeature-selective neuronsmotion detectorsthree-dimensional structurevisual systembinocular disparitybehavioral roleretinal imagesclasses of neuronsvisual neuronsrelative distanceneural propertiesvisual cuesin vivo two-photon microscopydistance-dependent behaviorconsistent with reliancebehavioral assaysAge-specific regulation of sociability by hypothalamic Agrp neurons
Iyilikci O, Kim L, Zimmer M, Bober J, Li Y, Pelts M, Santana G, Dietrich M. Age-specific regulation of sociability by hypothalamic Agrp neurons. Current Biology 2025, 35: 4522-4536.e6. PMID: 40907492, PMCID: PMC12802583, DOI: 10.1016/j.cub.2025.08.014.Peer-Reviewed Original ResearchConceptssocial behaviorAgRP neuronsneuronal activityregulation of sociabilitysocial isolationhypothalamic AgRP neuronsneural mechanismsintact olfactionAgRP neuron activityage-specific regulationin adulthoodrat pupssociabilityarcuate nucleusadolescentsyoung miceAgRPadulthoodhomeostatic regulationneuronshomeostatic mechanismsadult malesadultsdevelopmental stagesisolatesDivergent synaptic dynamics originate parallel pathways for computation and behavior in an olfactory circuit
Kim H, Santana G, Sancer G, Emonet T, Jeanne J. Divergent synaptic dynamics originate parallel pathways for computation and behavior in an olfactory circuit. Current Biology 2025, 35: 3146-3162.e8. PMID: 40541186, PMCID: PMC12235717, DOI: 10.1016/j.cub.2025.05.051.Peer-Reviewed Original Researchlateral horn neuronspostsynaptic neuronsprojection neuronsDrosophila olfactory systemcalcium buffer EGTAspike thresholdolfactory circuitssensory processingolfactory systemodor attractivenessinformation streamscentral circuitscellular mechanismssynaptic dynamicsspecialized computersneuronssubtractive adaptationdepressionsynapsescomputerefficient wayprocessing pathwaygain controlpresynaptic specializationsbehavior
2024
Neurons for infant social behaviors in the mouse zona incerta
Li Y, Liu Z, Santana G, Capaz A, Doumazane E, Gao X, Renier N, Dietrich M. Neurons for infant social behaviors in the mouse zona incerta. Science 2024, 385: 409-416. PMID: 39052814, PMCID: PMC12917754, DOI: 10.1126/science.adk7411.Peer-Reviewed Original ResearchConceptsinfant social behaviorsocial behaviorzona incertasomatostatin-expressing neuronsneural basisinfant behaviorbehavioral distressemotional developmentmaternal presenceneural activity manipulationfacilitation of learningbrain centerssocial interactionpopulations of neuronsinfant mouse brainpreweaning micemouse brainneuronsinfantsmiceactive manipulationbehaviormothersdistressincertaSqueakOut: Autoencoder-based segmentation of mouse ultrasonic vocalizations.
Santana GM, Dietrich MO. SqueakOut: Autoencoder-based segmentation of mouse ultrasonic vocalizations. BioRxiv 2024 PMID: 38712291, DOI: 10.1101/2024.04.19.590368.Peer-Reviewed Original Research
2021
Deficiency of the paternally inherited gene Magel2 alters the development of separation‐induced vocalization and maternal behavior in mice
Ortiz G, Santana GM, Dietrich MO. Deficiency of the paternally inherited gene Magel2 alters the development of separation‐induced vocalization and maternal behavior in mice. Genes Brain & Behavior 2021, 21: e12776. PMID: 34812568, PMCID: PMC9744533, DOI: 10.1111/gbb.12776.Peer-Reviewed Original ResearchConceptsorigin-specific mannergenomic imprintingmouse developmentpaternal genesmammalian offspringdeficient offspringloss of Magel2specific mannergene Magel2genesoffspring resultsMAGEL2combined expressionoffspringaltered behaviorseparation-induced vocalizationsvocal behaviorexpressionmammalspostnatal developmentgrowthimprintingpup growthLow‐power fast Fourier transform hardware architecture combining a split‐radix butterfly and efficient adder compressors
Ferreira G, Paim G, Rocha L, Santana G, Neuenfeld R, Costa E, Bampi S. Low‐power fast Fourier transform hardware architecture combining a split‐radix butterfly and efficient adder compressors. IET Computers & Digital Techniques 2021, 15: 230-240. DOI: 10.1049/cdt2.12015.Peer-Reviewed Original Research
2020
Framework-based Arithmetic Datapath Generation to Explore Parallel Binary Multipliers
Rocha L, Paim G, Santana G, Costa E, Bampi S. Framework-based Arithmetic Datapath Generation to Explore Parallel Binary Multipliers. Journal Of Integrated Circuits And Systems 2020, 15: 1-10. DOI: 10.29292/jics.v15i3.91.Peer-Reviewed Original ResearchExploring high-order adder compressors for power reduction in sum of absolute differences architectures for real-time UHD video encoding
Paim G, Santana G, Abreu B, Rocha L, Grellert M, da Costa E, Bampi S. Exploring high-order adder compressors for power reduction in sum of absolute differences architectures for real-time UHD video encoding. Journal Of Real-Time Image Processing 2020, 17: 1735-1754. DOI: 10.1007/s11554-019-00939-x.Peer-Reviewed Original Research
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Mailing Address
Neuroscience graduate students
Bass Receiving Center, Attn: Gustavo Santana (Emonet Lab), 266 Whitney Avenue
New Haven, CT 06511
United States
Locations
Room C155
Lab
Yale Science Building
260 Whitney Avenue
New Haven, CT 06511