Emily Sirotich
About
Biography
Dr. Emily Sirotich is a health research methodologist and clinical epidemiologist. Dr. Sirotich graduated with a PhD in Health Research Methodology from McMaster University in Hamilton, Canada.
She is an expert in rare disease research methods, novel data collection methods, and patient/community engagement. Dr. Sirotich is also a Steering Committee member of the COVID-19 Global Rheumatology Alliance and Board Member of the Canadian Arthritis Patient Alliance.
Last Updated on February 27, 2026.
Education & Training
- PhD
- McMaster University, Health Research Methodology (2022)
- BSc (Hon)
- University of Toronto, Immunology, Health Studies, Human Biology (2018)
Research
Publications
Featured Publications
Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology
Sirotich E, Guyatt G, Gabe C, Ye Z, Beck C, Breakey V, Cooper N, Cuker A, Charness J, de Wit K, DiRaimo J, Fein S, Grace R, Hassan Z, Jamula E, Kang M, Manski C, O'Connor C, Pai M, Paynter D, Porter S, Pruitt B, Strachan G, Webert K, Yan J, Kelton J, Bakchoul T, Arnold D. Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology. Journal Of Thrombosis And Haemostasis 2021, 19: 2082-2088. PMID: 34327824, DOI: 10.1111/jth.15368.Peer-Reviewed Original ResearchConceptsImmune thrombocytopeniaSevere thrombocytopeniaGuideline panelCritical anatomical sitesLow platelet countISTH SSC SubcommitteeBleeding eventsMajor bleedsOngoing bleedPlatelet immunologyCompartment syndromeHemodynamic instabilityRespiratory compromisePhysiologic riskPlatelet countAutoimmune diseasesUrgent treatmentPatient representativesAnatomical sitesThrombocytopeniaUpcoming guidelinesPatientsBleedStandardized definitionsClinical expertsRemoving barriers and disparities in health: lessons from the COVID-19 pandemic
Sirotich E, Hausmann J. Removing barriers and disparities in health: lessons from the COVID-19 pandemic. Nature Reviews Rheumatology 2020, 17: 125-126. PMID: 33028959, PMCID: PMC7540430, DOI: 10.1038/s41584-020-00524-8.Peer-Reviewed Original ResearchPerformance characteristics of platelet autoantibody testing for the diagnosis of immune thrombocytopenia using strict clinical criteria
Gabe C, Sirotich E, Li N, Ivetic N, Nazy I, Smith J, Kelton J, Arnold D. Performance characteristics of platelet autoantibody testing for the diagnosis of immune thrombocytopenia using strict clinical criteria. British Journal Of Haematology 2021, 194: 439-443. PMID: 34109621, DOI: 10.1111/bjh.17566.Peer-Reviewed Original ResearchConceptsPlatelet autoantibody testingImmune thrombocytopeniaAutoantibody testingPlatelet autoantibodiesITP patientsDiagnosis of ITPCertain patient subsetsAnti-glycoprotein IIb/IIIaStrict clinical criteriaHigh pretest probabilityAntigen capture assayIIb/IIIaPatient subsetsClinical criteriaPretest probabilityTreatment responsePatientsHigher optical density valuesOptical density valuesThrombocytopeniaAutoantibodiesCapture assayDiagnosisSpecificityTestingPutting patients at the centre of COVID-19 research
Sirotich E. Putting patients at the centre of COVID-19 research. Nature 2020 PMID: 32710008, DOI: 10.1038/d41586-020-02226-3.Peer-Reviewed Original Research
2026
Understanding caregiver vaccine hesitancy and experiences in children with paediatric rheumatic diseases: results from the C19-GRA Global Pediatric Survey
Ashoor M, Kennedy K, Knapp E, Wallace J, Howard R, Alvarez M, Fabi M, Franco L, Sirotich E, Hausmann J, Alliance C. Understanding caregiver vaccine hesitancy and experiences in children with paediatric rheumatic diseases: results from the C19-GRA Global Pediatric Survey. EULAR Rheumatology Open 2026, 2: 297-305. DOI: 10.1016/j.ero.2026.01.010.Peer-Reviewed Original ResearchLong-term COVID-19 outcomesPaediatric rheumatic diseasesAdverse eventsCOVID-19 vaccination ratesVaccination ratesPediatric surveyCOVID-19 outcomesCaregiver-reported dataRheumatic diseasesPostacute sequelaeChildren aged <Multisystem inflammatory syndromeEligible respondentsPatient organisationsVaccine hesitancyCaregiversCOVID-19 complicationsLong-term COVID-19 complicationsInflammatory syndromeCOVID-19 infectionHealthy childrenCOVID-19Vaccine adverse eventsCOVID-19 symptomsParental hesitancyPerioperative iron therapy for women undergoing gynecological procedures: a systematic review and meta-analysis
MacLean B, Lim J, Sirotich E, Chowdhury S, Watson M, Pai M, Gabarin N, Rochwerg B, Luketic L, Liu Y, Hillis C, Sokolov E, Arnold D, Zeller M. Perioperative iron therapy for women undergoing gynecological procedures: a systematic review and meta-analysis. Blood Red Cells & Iron 2026, 100067. DOI: 10.1016/j.brci.2026.100067.Peer-Reviewed Original ResearchRandomized Controlled TrialsIron therapyOral ironGynecologic surgeryIV ironObservational studyGynecologic proceduresIron deficiency anemiaCochrane riskRisk of Bias 2 toolSystematic reviewStandard of carePerioperative hemoglobin concentrationCochrane Risk of Bias 2 toolRandom-effects methodRisk of biasDeficiency anemiaObstetric proceduresPregnant womenClinical benefitMajor surgeryAdverse eventsPost-operationPrimary outcomeSurgeryAssessing the Impact of an Introductory Medical American Sign Language (ASL) Seminar on the ASL Knowledge and Competence of Healthcare Students
Malik D, Zeitoun S, Conlin F, Sirotich E, Schwartz N. Assessing the Impact of an Introductory Medical American Sign Language (ASL) Seminar on the ASL Knowledge and Competence of Healthcare Students. Medical Science Educator 2026, 1-8. DOI: 10.1007/s40670-026-02658-y.Peer-Reviewed Original ResearchAmerican Sign LanguageHealthcare studentsPost-workshop surveyHealthcare providersAmerican Sign Language gesturesHealthcare professional studentsPhysician assistant studentsSign languageHealthcare disparitiesProfessional studentsWorkshop completionHard of hearingMedical studentsPrimary languageHealthcareAssistant studentsPatient populationProvidersConfidenceLanguageAttendeesFluencyWorkshopEducationPre-Guideline on the emergency management of critical bleeding in patients with immune thrombocytopenia.
Chowdhury S, Sirotich E, Guyatt G, Modi D, Cuker A, Breakey V, Grace R, Pai M, Beck C, Yan J, Porter S, Kang M, Webert K, O'Connor C, Pruitt B, DiRaimo J, Paynter D, Strachan G, St John M, Molnar L, Arnold D. Guideline on the emergency management of critical bleeding in patients with immune thrombocytopenia. Blood Advances 2026 PMID: 41637560, DOI: 10.1182/bloodadvances.2025018818.Peer-Reviewed Original ResearchHigh-dose corticosteroidsImmune thrombocytopeniaCritical bleedingTPO-RAsPlatelet transfusionsTranexamic acidLife-threatening natureMulticentre retrospective cohort studyHigh-dose IVIGThrombopoietin receptor agonistsConditional recommendationManagement of critical bleedingAdult immune thrombocytopeniaGRADE Evidence-to-Decision frameworksPediatric immune thrombocytopeniaRecombinant factor VIIaClinical expertsEmergency department nursesEvidence-to-decision frameworkRetrospective cohort studyGrading of recommendations assessmentRisk of thrombosisTreatment of adultsManagement of adultsEmergency department physicians
2025
Performance Comparison of Large Language Models Versus Board‐Certified Dermatologists on CME‐Accredited Self‐Assessments: A Cross‐Sectional Study
Sirotich E, Cohen J, Gehlhausen J. Performance Comparison of Large Language Models Versus Board‐Certified Dermatologists on CME‐Accredited Self‐Assessments: A Cross‐Sectional Study. International Journal Of Dermatology 2025, 65: 831-833. PMID: 41173811, DOI: 10.1111/ijd.70111.Peer-Reviewed Original ResearchDevelopment of National Clinical Practice Guidelines for Transition in Rheumatology
Herrington J, Luca N, Linsley E, McColl J, Gakhal N, Rozenblyum E, Pardo J, Hazlewood G, Sirotich E, Garner S, Batthish M, Bessey J, Liu K, Jarvis P, Broderick L, Spiegel L, Matsos M, Stringer E. Development of National Clinical Practice Guidelines for Transition in Rheumatology. The Journal Of Rheumatology 2025, 52: 118-119. DOI: 10.3899/jrheum.2025-0314.153.Peer-Reviewed Original ResearchClinical practice guidelinesBest practice statementsPractice guidelinesJournal of Clinical EpidemiologyConsensus meetingNational clinical practice guidelinesEvidence to decisionHealth care providersGuidelines Working GroupWorking GroupOnline surveyComprehensive clinical practice guidelinesGRADE-ADOLOPMENTPhysiotherapist practitionersCare providersAdult careDelphi panelistsMulti-phase projectClinical epidemiologyPractice statementsConsensus processOrientation sessionConditional recommendationTransition of young peopleTransition of youth
Academic Achievements & Community Involvement
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