Diara Santiago Gonzalez, PhD
she/her/hers
Electron Microscopy Lab ManagerCards
About
Research
Publications
2023
The expression of ceruloplasmin in astrocytes is essential for postnatal myelination and myelin maintenance in the adult brain.
Cheli VT, Sekhar M, Santiago González DA, Angeliu CG, Denaroso GE, Smith Z, Wang C, Paez PM. The expression of ceruloplasmin in astrocytes is essential for postnatal myelination and myelin maintenance in the adult brain. Glia 2023, 71: 2323-2342. PMID: 37269227, DOI: 10.1002/glia.24424.Peer-Reviewed Original Research In PressTransferrin Receptor Is Necessary for Proper Oligodendrocyte Iron Homeostasis and Development.
Cheli VT, Santiago González DA, Wan R, Rosenblum SL, Denaroso GE, Angeliu CG, Smith Z, Wang C, Paez PM. Transferrin Receptor Is Necessary for Proper Oligodendrocyte Iron Homeostasis and Development. J Neurosci 2023, 43: 3614-3629. PMID: 36977582, DOI: 10.1523/JNEUROSCI.1383-22.2023.Peer-Reviewed Original Research In Press
2021
H-ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination.
Cheli VT, Santiago González DA, Wan Q, Denaroso G, Wan R, Rosenblum SL, Paez PM. H-ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination. Glia 2021, 69: 2981-2998. PMID: 34460113, DOI: 10.1002/glia.24083.Peer-Reviewed Original Research In PressCeruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems.
Santiago González DA, Cheli VT, Rosenblum SL, Denaroso G, Paez PM. Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems. Redox Biol 2021, 46: 102118. PMID: 34474395, DOI: 10.1016/j.redox.2021.102118.Peer-Reviewed Original Research In Press
2020
Impaired Postnatal Myelination in a Conditional Knockout Mouse for the Ferritin Heavy Chain in Oligodendroglial Cells.
Wan R, Cheli VT, Santiago-González DA, Rosenblum SL, Wan Q, Paez PM. Impaired Postnatal Myelination in a Conditional Knockout Mouse for the Ferritin Heavy Chain in Oligodendroglial Cells. J Neurosci 2020, 40: 7609-7624. PMID: 32868463, DOI: 10.1523/JNEUROSCI.1281-20.2020.Peer-Reviewed Original Research In PressDeletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice.
Zamora NN, Cheli VT, Santiago González DA, Wan R, Paez PM. Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice. J Neurosci 2020, 40: 3332-3347. PMID: 32169969, DOI: 10.1523/JNEUROSCI.1644-19.2020.Peer-Reviewed Original Research In Press
2019
Iron Metabolism in the Peripheral Nervous System: The Role of DMT1, Ferritin, and Transferrin Receptor in Schwann Cell Maturation and Myelination.
Santiago González DA, Cheli VT, Wan R, Paez PM. Iron Metabolism in the Peripheral Nervous System: The Role of DMT1, Ferritin, and Transferrin Receptor in Schwann Cell Maturation and Myelination. J Neurosci 2019, 39: 9940-9953. PMID: 31676601, DOI: 10.1523/JNEUROSCI.1409-19.2019.Peer-Reviewed Original Research In Press
2018
Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome.
Cheli VT, Santiago González DA, Zamora NN, Lama TN, Spreuer V, Rasmusson RL, Bett GC, Panagiotakos G, Paez PM. Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome. Glia 2018, 66: 2324-2339. PMID: 30151840, DOI: 10.1002/glia.23468.Peer-Reviewed Original Research In PressThe Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells.
Cheli VT, Santiago González DA, Marziali LN, Zamora NN, Guitart ME, Spreuer V, Pasquini JM, Paez PM. The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells. J Neurosci 2018, 38: 9142-9159. PMID: 30190412, DOI: 10.1523/JNEUROSCI.1447-18.2018.Peer-Reviewed Original Research In PressMuscarinic Receptor M(3)R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells.
Welliver RR, Polanco JJ, Seidman RA, Sinha AK, O'Bara MA, Khaku ZM, Santiago González DA, Nishiyama A, Wess J, Feltri ML, Paez PM, Sim FJ. Muscarinic Receptor M(3)R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells. J Neurosci 2018, 38: 6921-6932. PMID: 29959237, DOI: 10.1523/JNEUROSCI.1862-17.2018.Peer-Reviewed Original Research In Press
Get In Touch
Contacts
Locations
Renal and Electron Microscopy Lab
Lab
Brady Memorial Laboratory
310 Cedar Street, Rm B20D
New Haven, CT 06510