Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsDavid Baddeley, PhD
About
Research
Publications
2025
Resolution in super-resolution microscopy – facts, artifacts, technological advancements and biological applications
Prakash K, Baddeley D, Eggeling C, Fiolka R, Heintzmann R, Manley S, Radenovic A, Shroff H, Smith C, Schermelleh L. Resolution in super-resolution microscopy – facts, artifacts, technological advancements and biological applications. Journal Of Cell Science 2025, 138: jcs263567. PMID: 40421932, PMCID: PMC12148039, DOI: 10.1242/jcs.263567.Peer-Reviewed Original ResearchGetting the most out of super-resolution using high throughput imaging and incorporating prior knowledge
Baddeley D. Getting the most out of super-resolution using high throughput imaging and incorporating prior knowledge. 2025 DOI: 10.14293/apmc13-2025-0083.Peer-Reviewed Original Research
2024
Resolution in super-resolution microscopy — definition, trade-offs and perspectives
Prakash K, Baddeley D, Eggeling C, Fiolka R, Heintzmann R, Manley S, Radenovic A, Smith C, Shroff H, Schermelleh L. Resolution in super-resolution microscopy — definition, trade-offs and perspectives. Nature Reviews Molecular Cell Biology 2024, 25: 677-682. PMID: 38951703, DOI: 10.1038/s41580-024-00755-7.Peer-Reviewed Original ResearchElectrophysiology and 3D‐imaging reveal properties of human intracardiac neurons and increased excitability with atrial fibrillation
Ashton J, Prince B, Sands G, Argent L, Anderson M, Smith J, Tedoldi A, Ahmad A, Baddeley D, Pereira A, Lever N, Ramanathan T, Smaill B, Montgomery J. Electrophysiology and 3D‐imaging reveal properties of human intracardiac neurons and increased excitability with atrial fibrillation. The Journal Of Physiology 2024, 603: 1923-1939. PMID: 38687681, PMCID: PMC11955863, DOI: 10.1113/jp286278.Peer-Reviewed Original ResearchInduced action potential firingAction potential firingGP neuronsGanglionated plexiAtrial fibrillationPhenotypic neuronsAF patientsAutonomic neuronsPotential firingWhole cell patch-clamp techniqueAutonomic influencesAction potential firing rateIncreased synaptic densityAction potential accommodationSynaptic densityPatch-clamp techniqueAction potential kineticsOpen heart surgeryEpicardial adipose tissueInitiation of AFAutonomic ganglionated plexiControl of cardiac functionAction potential rateAutonomic nervous systemNoradrenergic phenotypeA correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context
Bao Y, Marin Z, Zhang C, Neugebauer K, Baddeley D, Shribak M, Bewersdorf J. A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context. Biophysical Journal 2024, 123: 290a. DOI: 10.1016/j.bpj.2023.11.1808.Peer-Reviewed Original Research