Danielle Goldman, MS
PhD Student, Interdepartmental Neuroscience ProgramAbout
Titles
PhD Student, Interdepartmental Neuroscience Program
Biography
Danielle is a PhD candidate conducting her research in the Mood Disorders Research Program.
Born and raised in New York City, she initiated her research curiosities while in high school, where she studied the role of GABA in the dimensionality of symptoms in adolescents with Major Depressive Disorder and Generalized Anxiety Disorder in the laboratory of Dr. Vilma Gabbay. For this work, she was named a 2012 finalist in both the prestigious Intel Science Talent Search and Intel Science and Engineering Fair.
She continued this work while in college at Columbia University, extending her experience in fMRI and genetic techniques for studying developmental psychopathology. Also while at Columbia, she diversified her interests by delving into the realm of development of normative emotion regulation strategies under the mentorship of Dr. Kevin Ochsner, as well as the realm of prenatal biomarkers of neurodevelopmental risk, under the mentorship of Dr. Frances Champagne.
After graduating with a bachelor’s degree in Neuroscience and Behavior, she loved the academic and collaborative environment so much that she remained at Columbia to pursue her interdisciplinary interests. She received her master’s degree in Bioethics where her thesis work focused on the utility of genetic technologies in diagnosing heterogeneous pediatric neurology patients, with a secondary interest in the utility of neuroimaging evidence in the juvenile justice system.
She has presented her work academically at numerous national and international conferences (SOBP, ISDP, Flux, AACAP), as well as in more widely public settings (social media correspondent for Society for Science and the Public), and continues to eagerly disseminate her findings and passion for science.
Danielle now conducts research under the mentorship of Dr. Hilary Blumberg where her research interests broadly revolve around examining the neurobiological correlates of, and risk factors for, abnormal developmental trajectories in mood-related psychopathology.
Outside of the laboratory, Danielle is ardently passionate about outreach and mentorship opportunities (INP Outreach Executive Committee, Yale Science Diplomats, Flipped Science Fair, INP Recruitment Student Committee).
Education & Training
- MS
- Columbia University, Bioethics (2018)
- BA
- Columbia University, Neuroscience and Behavior (2016)
- BS
- The Bronx High School of Science (HS Diploma) (2012)
Research
Overview
Medical Research Interests
ORCID
0000-0003-1916-7372
Research at a Glance
Yale Co-Authors
Publications Timeline
Hilary Blumberg, MD
Todd Constable, PhD
Dustin Scheinost, PhD, BS
Anjali Sankar
Brian Pittman
Xilin Shen, PhD
Publications
2025
PREDICTING DEPRESSED AND ELEVATED MOOD SYMPTOMATOLOGY IN BIPOLAR DISORDER USING BRAIN FUNCTIONAL CONNECTOMES
Sankar *, Shen X, Colic L, Goldman D, Villa L, Kim J, Pittman B, Scheinost D, Constable R, Blumberg H. PREDICTING DEPRESSED AND ELEVATED MOOD SYMPTOMATOLOGY IN BIPOLAR DISORDER USING BRAIN FUNCTIONAL CONNECTOMES. The International Journal Of Neuropsychopharmacology 2025, 28: i15-i15. PMCID: PMC11814904, DOI: 10.1093/ijnp/pyae059.027.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingBipolar disorderMood symptomatologyMood symptomsFunctional connectomeYoung Mania Rating ScaleFunctional magnetic resonance imaging dataPredictors of functional impairmentEmotion processing taskMania Rating ScaleMood symptom severityMood symptom scoresBrain functional connectomeMagnetic resonance imaging dataBrain function disturbancesHamilton DepressionPredicting depressionSymptom severityRating ScaleFunctional impairmentDisordersMoodSymptomatologyProcessing tasksDepression
2024
Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults
Colic L, Sankar A, Goldman D, Kim J, Blumberg H. Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults. Molecular Psychiatry 2024, 30: 1089-1101. PMID: 39333385, PMCID: PMC11835756, DOI: 10.1038/s41380-024-02758-4.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingVentral prefrontal cortexBipolar disorderPrefrontal cortexNeurodevelopmental modelBrain systemsMood statesFunctional magnetic resonance imaging studyModel of bipolar disorderProcessing of rewardAcute mood statesRegulation of emotionVentral cortical regionsYoung adultsFunctional imaging findingsTrait vulnerabilityMood episodesSyndromal BDNeuroimaging evidenceFunctional neuroanatomyBrain differencesNeuroimaging studiesNeurodevelopmental mechanismsPrecentral gyrusBrain regions
2022
Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders
Colic L, Villa L, Dauvermann M, van Velzen L, Sankar A, Goldman D, Panchal P, Kim J, Quatrano S, Spencer L, Constable R, Suckling J, Goodyer I, Schmaal L, van Harmelen A, Blumberg H. Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders. JCPP Advances 2022, 2 PMID: 36817186, PMCID: PMC9937714, DOI: 10.1002/jcv2.12118.Peer-Reviewed Original ResearchHypertensive disorders during pregnancy and polycystic ovary syndrome are associated with child communication and social skills in a sex-specific and androgen-dependent manner
Firestein MR, Romeo RD, Winstead H, Goldman DA, Grobman WA, Haas DM, Parry S, Reddy UM, Silver RM, Wapner RJ, Champagne FA. Hypertensive disorders during pregnancy and polycystic ovary syndrome are associated with child communication and social skills in a sex-specific and androgen-dependent manner. Frontiers In Endocrinology 2022, 13: 1000732. PMID: 36246897, PMCID: PMC9559211, DOI: 10.3389/fendo.2022.1000732.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsPolycystic ovary syndromeHyperandrogenic disordersOvary syndromeMaternal testosteroneHypertensive disordersNulliparous Pregnancy Outcomes StudyCohort study designPregnancy Outcomes StudyYears of ageAutism spectrum disorderSex-specific associationsHigher testosterone levelsChildren's brain developmentNeurodevelopmental outcomesAndrogen-dependent mannerSecond trimesterPrenatal exposureMonitoring MothersTestosterone levelsOutcome studiesPregnancyFemale controlsMaternal plasmaTestosteroneChild communicationA Multimodal Imaging Approach to Identify Brain Connectivity Targets for Early Detection, and to Reduce Symptoms and Prevent Progression and Suicide Risk, in Bipolar Disorder
Goldman D, Sankar A, Colic L, Villa L, Kim J, Pittman B, Constable R, Scheinost D, Blumberg H. A Multimodal Imaging Approach to Identify Brain Connectivity Targets for Early Detection, and to Reduce Symptoms and Prevent Progression and Suicide Risk, in Bipolar Disorder. Biological Psychiatry 2022, 91: s38-s39. DOI: 10.1016/j.biopsych.2022.02.114.Peer-Reviewed Original Research
2021
A Graph Theoretical Connectome Measure to Assess Whole Brain Functional Connectivity Disturbances Associated With Suicide Attempts in Bipolar Disorder
Sankar A, Scheinost D, Goldman D, Drachman R, Colic L, Villa L, Kim J, Gonzalez Y, Marcelo I, Shinomiya M, Pittman B, Lacadie C, Oquendo M, Constable R, Blumberg H. A Graph Theoretical Connectome Measure to Assess Whole Brain Functional Connectivity Disturbances Associated With Suicide Attempts in Bipolar Disorder. Biological Psychiatry 2021, 89: s296. DOI: 10.1016/j.biopsych.2021.02.737.Peer-Reviewed Original Research
2020
Brain Circuitry Targets to Interrupt the Development of Suicide Thoughts and Behaviors
Colic L, Lippard E, Goldman D, Sankar A, Blumberg H. Brain Circuitry Targets to Interrupt the Development of Suicide Thoughts and Behaviors. Biological Psychiatry 2020, 87: s23. DOI: 10.1016/j.biopsych.2020.02.084.Peer-Reviewed Original ResearchSelf-Reported Child Maltreatment, History of Suicide Attempts and Surface Area in Adults With Bipolar Disorder
Colic L, Sankar A, Clark A, Rathi D, Goldman D, Lippard E, Blumberg H. Self-Reported Child Maltreatment, History of Suicide Attempts and Surface Area in Adults With Bipolar Disorder. Biological Psychiatry 2020, 87: s441. DOI: 10.1016/j.biopsych.2020.02.1124.Peer-Reviewed Original ResearchMood State Differences in Intrinsic Connectivity Distribution of Adolescents and Young Adults With Bipolar Disorder
Goldman D, Sankar A, Colic L, Spencer L, Lacadie C, Scheinost D, Constable R, Blumberg H. Mood State Differences in Intrinsic Connectivity Distribution of Adolescents and Young Adults With Bipolar Disorder. Biological Psychiatry 2020, 87: s416-s417. DOI: 10.1016/j.biopsych.2020.02.1063.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Honors
honor Multidisciplinary Pre-doctoral Training Program Grant Awardee
07/01/2021Yale University AwardYale Center for Clinical InvestigationDetailsUnited Stateshonor Early Career Policy Ambassador
02/01/2021International AwardSociety for NeuroscienceDetailsUnited Stateshonor Gruber Science Fellowship
08/20/2018Yale University AwardGruber FoundationDetailsUnited Stateshonor Precision Medicine: Ethics, Politics, and Culture Graduate Fellowship
08/21/2017National AwardColumbia University Center for the Study of Social DifferenceDetailsUnited Stateshonor Abraham Taub Scholarship
08/25/2014Regional AwardColumbia UniversityDetailsUnited States