Cat McCann, PhD

they/them/theirs

Academic Coordinator and Registrar

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Contact Info

cat.mccann@yale.edu

Pharmacology

333 Cedar St, SHM B 208B

New Haven, CT 06511

United States

Education

PhD
Johns Hopkins University School of Medicine, Cellular and Molecular Physiology (2021)

BSc
Worcester Polytechnic Institute, Biochemistry (2013)

About

Titles

Academic Coordinator and Registrar

Departments & Organizations

All Institutions
Pharmacology

Education & Training

PhD: Johns Hopkins University School of Medicine, Cellular and Molecular Physiology (2021)

BSc: Worcester Polytechnic Institute, Biochemistry (2013)

Research

Research at a Glance

Publications Timeline

A big-picture view of Cat McCann's research output by year.

7Publications

Publications

2022

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner.
McCann CJ, Hasan NM, Padilla-Benavides T, Roy S, Lutsenko S. Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner. Front Mol Biosci 2022, 9: 1067490. PMID: 36545508, DOI: 10.3389/fmolb.2022.1067490.
Peer-Reviewed Original Research
The mitochondrial Cu(+) transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro.
McCann C, Quinteros M, Adelugba I, Morgada MN, Castelblanco AR, Davis EJ, Lanzirotti A, Hainer SJ, Vila AJ, Navea JG, Padilla-Benavides T. The mitochondrial Cu(+) transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro. Front Mol Biosci 2022, 9: 1037941. PMID: 36438658, DOI: 10.3389/fmolb.2022.1037941.
Peer-Reviewed Original Research
ZIP11 Regulates Nuclear Zinc Homeostasis in HeLa Cells and Is Required for Proliferation and Establishment of the Carcinogenic Phenotype.
Olea-Flores M, Kan J, Carlson A, Syed SA, McCann C, Mondal V, Szady C, Ricker HM, McQueen A, Navea JG, Caromile LA, Padilla-Benavides T. ZIP11 Regulates Nuclear Zinc Homeostasis in HeLa Cells and Is Required for Proliferation and Establishment of the Carcinogenic Phenotype. Front Cell Dev Biol 2022, 10: 895433. PMID: 35898402, DOI: 10.3389/fcell.2022.895433.
Peer-Reviewed Original Research

2020

Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties.
Roy S, McCann CJ, Ralle M, Ray K, Ray J, Lutsenko S, Jayakanthan S. Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties. Sci Rep 2020, 10: 13487. PMID: 32778786, DOI: 10.1038/s41598-020-70366-7.
Peer-Reviewed Original Research

2019

Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein.
McCann CJ, Jayakanthan S, Siotto M, Yang N, Osipova M, Squitti R, Lutsenko S. Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein. Metallomics 2019, 11: 1128-1139. PMID: 31070637, DOI: 10.1039/c9mt00057g.
Peer-Reviewed Original Research
Chapter 4 - Biochemical and Cellular Properties of ATP7B Variants
Samuel Jayakanthan, Courtney McCann, Svetlana Lutsenko
Chapters

2013

The mechanism of Cu+ transport ATPases: interaction with CU+ chaperones and the role of transient metal-binding sites.
Padilla-Benavides T, McCann CJ, Argüello JM. The mechanism of Cu+ transport ATPases: interaction with CU+ chaperones and the role of transient metal-binding sites. J Biol Chem 2013, 288: 69-78. PMID: 23184962, DOI: 10.1074/jbc.M112.420810.
Peer-Reviewed Original Research

Academic Achievements & Community Involvement

Get In Touch

Contacts

cat.mccann@yale.edu

Mailing Address

Pharmacology

333 Cedar St, SHM B 208B

New Haven, CT 06511

United States

Locations

Sterling Hall of Medicine
Academic Office
333 Cedar Street, Wing B, Fl 2, Rm 208
New Haven, CT 06510
Get Directions

Events

Apr 202616Tomorrow

Yale Only
12:00 PM1:00 PM
Aashish Manglik, MD, PhD
Yale Pharmacology presents: "Cracking Codes in Cellular Communication"
Pharmacology Seminar Series
Brady Memorial Laboratory
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Apr 202623Thursday

Yale Only
12:00 PM1:00 PM
Forest White, PhD
Yale Pharmacology Seminar Series
"Cell-Type Specific Proteomics and Immunopeptidomics Reveals New Therapeutic Targets"
Brady Memorial Laboratory
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Apr 202630Thursday

Yale Only
4:00 PM5:00 PM
Mitch Lazar, MD, PhD
Yale Pharmacology presents the 2026 Arnold D. Welch Lecture: "Nuclear Receptors and the Circadian Regulation of Transcription and Metabolism"
The Anlyan Center
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May 20267Thursday

Yale Only
12:00 PM1:00 PM
Cynthia Wolberger, PhD
Yale Pharmacology presents: "Decoding the Molecular Mechanisms of Histone Modifications"
Pharmacology Seminar Series
Brady Memorial Laboratory
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See All Events

Contact Info

Education

Titles

Departments & Organizations

Education & Training

Research at a Glance

Publications Timeline

Publications

2022

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner.

The mitochondrial Cu(+) transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro.

ZIP11 Regulates Nuclear Zinc Homeostasis in HeLa Cells and Is Required for Proliferation and Establishment of the Carcinogenic Phenotype.

2020

Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties.

2019

Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein.

Chapter 4 - Biochemical and Cellular Properties of ATP7B Variants

2013

The mechanism of Cu+ transport ATPases: interaction with CU+ chaperones and the role of transient metal-binding sites.

Contacts

Locations

Sterling Hall of Medicine

Events

Yale Pharmacology presents: "Cracking Codes in Cellular Communication"

Yale Pharmacology Seminar Series

Yale Pharmacology presents the 2026 Arnold D. Welch Lecture: "Nuclear Receptors and the Circadian Regulation of Transcription and Metabolism"

Yale Pharmacology presents: "Decoding the Molecular Mechanisms of Histone Modifications"