Ariel Chao, MPH
About
Research
Publications
2024
Estimation and inference for causal spillover effects in egocentric-network randomized trials in the presence of network membership misclassification
Chao A, Spiegelman D, Buchanan A, Forastiere L. Estimation and inference for causal spillover effects in egocentric-network randomized trials in the presence of network membership misclassification. Biostatistics 2024, 26: kxaf009. PMID: 40159413, PMCID: PMC11955068, DOI: 10.1093/biostatistics/kxaf009.Peer-Reviewed Original ResearchConceptsHIV Prevention Trials NetworkBehavioral changesImpact of interventionsPopulation behavior changePeer-based strategiesRandomized trialsIntervention effectsBehavioral interventionsStudy designSpillover effectsInterventionTrials NetworkInvestigate finite sample propertiesAverage spillover effectFinite sample propertiesBehavioral trainingParticipantsLeverage peer influenceMisclassificationDisseminate informationInterference settingOutcomesPeer influenceSurrogate networksSample properties
2021
Effect of Availability of Transcatheter Aortic-Valve Implantation on Survival for all Patients With Severe Aortic Stenosis
Chao A, Picard M, Passeri J, Cui J, Nethery R, Wasfy J. Effect of Availability of Transcatheter Aortic-Valve Implantation on Survival for all Patients With Severe Aortic Stenosis. The American Journal Of Cardiology 2021, 149: 72-77. PMID: 33753034, DOI: 10.1016/j.amjcard.2021.03.016.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationSevere aortic stenosisAortic valve implantationAortic stenosisPatient ageAS patientsPatient populationLow riskSurgical aortic valve replacementAS patient populationsSevere AS patientsLow risk of deathAortic valve replacementCox regression modelsTAVI eraRisk of deathYears of ageRandomized Controlled TrialsMedian survivalOverall survivalSevere ASAS severityEchocardiography databaseValve replacementPre-TAVI era
2020
Early access to antiretroviral therapy versus standard of care among HIV‐positive participants in Eswatini in the public health sector: the MaxART stepped‐wedge randomized controlled trial
Khan S, Spiegelman D, Walsh F, Mazibuko S, Pasipamire M, Chai B, Reis R, Mlambo K, Delva W, Khumalo G, Zwane M, Fleming Y, Mafara E, Hettema A, Lejeune C, Chao A, Bärnighausen T, Okello V. Early access to antiretroviral therapy versus standard of care among HIV‐positive participants in Eswatini in the public health sector: the MaxART stepped‐wedge randomized controlled trial. Journal Of The International AIDS Society 2020, 23: e25610. PMID: 32949103, PMCID: PMC7507004, DOI: 10.1002/jia2.25610.Peer-Reviewed Original ResearchConceptsViral suppressionStandard of careAntiretroviral treatmentCox proportional hazards modelHealth systemART-naïve participantsHIV-positive patientsHIV-positive adultsViral load monitoringHIV-positive participantsAppropriate care managementProportional hazards modelEarly accessPublic sector health facilitiesHealth system effectsPublic health systemHealth system's abilityClinic transitionAntiretroviral therapyCD4 countCare retentionVL monitoringPublic health sectorDisease stageEndpoint rateMortality under early access to antiretroviral therapy vs. Eswatini’s national standard of care: the MaxART clustered randomized stepped‐wedge trial
Chao A, Spiegelman D, Khan S, Walsh F, Mazibuko S, Pasipamire M, Chai B, Reis R, Mlambo K, Delva W, Khumalo G, Zwane M, Fleming Y, Mafara E, Hettema A, Lejeune C, Bärnighausen T, Okello V. Mortality under early access to antiretroviral therapy vs. Eswatini’s national standard of care: the MaxART clustered randomized stepped‐wedge trial. HIV Medicine 2020, 21: 429-440. PMID: 32458567, DOI: 10.1111/hiv.12876.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyMortality rateDisease-related mortality rateCox proportional hazards modelCause mortality ratesStepped-wedge trialProportional hazards modelStepped-wedge designQuality of lifeEvidence of harmClinic transitionSecondary outcomesSOC participantsHealth clinicsLong-term consequencesImplementation trialHazards modelHIVStudy participantsMortalityHealth systemDecrease infectionEarly accessClinicTherapyLONGER SURVIVAL FOR ALL PATIENTS WITH SEVERE AORTIC STENOSIS ASSOCIATED WITH TAVR AVAILABILITY IN REAL-WORLD PRACTICE
Chao A, Picard M, Passeri J, Cui J, Nethery R, Wasfy J. LONGER SURVIVAL FOR ALL PATIENTS WITH SEVERE AORTIC STENOSIS ASSOCIATED WITH TAVR AVAILABILITY IN REAL-WORLD PRACTICE. Journal Of The American College Of Cardiology 2020, 75: 1246. DOI: 10.1016/s0735-1097(20)31873-8.Peer-Reviewed Original Research
2018
Outcomes and Resource Utilization in Robotic Mitral Valve Repair: Beyond the Learning Curve
Seo Y, Sanaiha Y, Bailey K, Aguayo E, Chao A, Shemin R, Benharash P. Outcomes and Resource Utilization in Robotic Mitral Valve Repair: Beyond the Learning Curve. Journal Of Surgical Research 2018, 235: 258-263. PMID: 30691804, DOI: 10.1016/j.jss.2018.10.007.Peer-Reviewed Original ResearchConceptsRobotic mitral valve repairMitral valve repairShorter length of stayLength of stayOperative timeValve repairComplication rateRoom costsLos Angeles Medical CenterLearning curveCross-clamp timeTraditional open approachInitial learning curveAssociated with lower oddsShorter lengthCardiac surgerySurgeon experienceMVRepAdult patientsOpen approachRoom timeSurgery timeMultivariate regression modelRobotic proceduresRobotic approach