Andrea Roberts, MD
Assistant Professor in Medicine (General Medicine)Cards
About
Research
Publications
2026
Association between depression and risk of colorectal cancer and polyps: A prospective cohort study from Nurses' Health Study II.
Tangpradubkiat P, Roberts A, Cardona B, Kim H, Ogino S, Giovannucci E, Song M, Chan A. Association between depression and risk of colorectal cancer and polyps: A prospective cohort study from Nurses' Health Study II. Cancer Epidemiology Biomarkers & Prevention 2026, of1-of11. PMID: 42132476, DOI: 10.1158/1055-9965.epi-25-1836.Peer-Reviewed Original ResearchNurses' Health Study IIRisk of colorectal cancerSerrated polypsAssociated with lower riskColorectal cancerConventional adenomasLower risk of colorectal cancerAssociated with serrated polypsOdds ratioHazard ratioAssociated with colorectal cancerStudy IIPhysician-diagnosed depressionColorectal cancer casesProspective cohort studyCox proportional hazards modelsColorectal carcinogenesisColorectal polypsProportional hazards modelMultivariate Cox proportional hazards modelColorectal cancer analysisAntidepressant usePolyp analysisChronic diseasesCohort studyMo1746 ASSOCIATION BETWEEN HISTORY OF CHILDHOOD ABUSE AND CONSTIPATION IN ADULTHOOD
Tangpradubkiat P, Roberts A, Wang Y, Wang K, Staller K, Chan A. Mo1746 ASSOCIATION BETWEEN HISTORY OF CHILDHOOD ABUSE AND CONSTIPATION IN ADULTHOOD. Gastrointestinal Endoscopy 2026, 103: s-1926-s-1927. DOI: 10.1016/s0016-5107(26)04555-4.Peer-Reviewed Original Research1030 ASSOCIATION BETWEEN DEPRESSION AND RISK OF COLORECTAL CANCER AND POLYPS: A PROSPECTIVE COHORT STUDY FROM NURSES’ HEALTH STUDY II
Tangpradubkiat P, Roberts A, Cardona B, Wang C, Kim H, Ogino S, Giovannucci E, Song M, Chan A. 1030 ASSOCIATION BETWEEN DEPRESSION AND RISK OF COLORECTAL CANCER AND POLYPS: A PROSPECTIVE COHORT STUDY FROM NURSES’ HEALTH STUDY II. Gastroenterology 2026, 170: s-176. DOI: 10.1016/s0016-5085(26)00754-7.Peer-Reviewed Original Research1030 ASSOCIATION BETWEEN DEPRESSION AND RISK OF COLORECTAL CANCER AND POLYPS: A PROSPECTIVE COHORT STUDY FROM NURSES’ HEALTH STUDY II
Tangpradubkiat P, Roberts A, Cardona B, Wang C, Kim H, Ogino S, Giovannucci E, Song M, Chan A. 1030 ASSOCIATION BETWEEN DEPRESSION AND RISK OF COLORECTAL CANCER AND POLYPS: A PROSPECTIVE COHORT STUDY FROM NURSES’ HEALTH STUDY II. Gastrointestinal Endoscopy 2026, 103: s-176. DOI: 10.1016/s0016-5107(26)00685-1.Peer-Reviewed Original ResearchMo1746 ASSOCIATION BETWEEN HISTORY OF CHILDHOOD ABUSE AND CONSTIPATION IN ADULTHOOD
Tangpradubkiat P, Roberts A, Wang Y, Wang K, Staller K, Chan A. Mo1746 ASSOCIATION BETWEEN HISTORY OF CHILDHOOD ABUSE AND CONSTIPATION IN ADULTHOOD. Gastroenterology 2026, 170: s-1926-s-1927. DOI: 10.1016/s0016-5085(26)04624-x.Peer-Reviewed Original ResearchAssociations between women’s childhood maltreatment and thyroid function before and during pregnancy
Vyas C, Wu B, Mahalingaiah S, Mukherjee R, Slopen N, Weisskopf M, Chavarro J, Roberts A. Associations between women’s childhood maltreatment and thyroid function before and during pregnancy. Scientific Reports 2026, 16: 19116. PMID: 42034820, PMCID: PMC13279924, DOI: 10.1038/s41598-026-48820-9.Peer-Reviewed Original ResearchThyroid-stimulating hormoneThyroid functionPregnant womenFT3 levelsPlasma thyroid-stimulating hormoneLow FT3 levelsThyroid function testsAnti-thyroperoxidase antibodiesAssociated with complicationsLow thyroid functionNurses' Health Study 3No significant associationThyroid dysfunctionTPOAb levelsFree triiodothyronineFree thyroxineMenstrual cycleEthnically diverse studiesMaternal childhood maltreatmentPregnancyFunction testsThyroidChildhood maltreatmentSevere childhood maltreatmentSignificant associationTowards scalable biomarker discovery in posttraumatic stress disorder: triangulating genomic and phenotypic evidence from a health system biobank
Lee Y, Zhang Y, Espinosa Dice A, Li J, Tubbs J, Feng Y, Ge T, Maihofer A, Nievergelt C, Smoller J, Koenen K, Roberts A, Slopen N. Towards scalable biomarker discovery in posttraumatic stress disorder: triangulating genomic and phenotypic evidence from a health system biobank. Molecular Psychiatry 2026, 1-10. PMID: 41946832, DOI: 10.1038/s41380-026-03553-z.Peer-Reviewed Original ResearchElectronic health recordsPolygenic risk scoresGenome-wide association studiesMass General BrighamPosttraumatic stress disorderEuropean ancestry genome-wide association studiesTwo-sample Mendelian randomization analysisLongitudinal electronic health recordsMendelian randomization analysisEuropean ancestry participantsHealth system biobankPolygenic scoring methodsStress disorderAncestry participantsHealth recordsBiobank studyClinical diagnosis of posttraumatic stress disorderRandomization analysisDiagnostic codesDiagnosis of posttraumatic stress disorderLaboratory traitsRisk scoreAssociation scansPrimary outcomeAssociation studies
2025
Corrigendum to “Posttraumatic stress disorder and epigenetic signatures of inflammation in middle-aged women” [Psychoneuroendocrinology 182 (2025) 107654]
Liu J, Ratanatharathorn A, Meir A, Murchland A, Zhu Y, Roberts A, Lawn R, Sumner J, Haneuse S, Liang L, Kubzansky L, Koenen K, Chibnik L. Corrigendum to “Posttraumatic stress disorder and epigenetic signatures of inflammation in middle-aged women” [Psychoneuroendocrinology 182 (2025) 107654]. Psychoneuroendocrinology 2025, 184: 107687. PMID: 41240613, PMCID: PMC12771398, DOI: 10.1016/j.psyneuen.2025.107687.Commentaries, Editorials and LettersPosttraumatic stress disorder and epigenetic signatures of inflammation in middle-aged women
Liu J, Ratanatharathorn A, Yaskolka Meir A, Murchland A, Zhu Y, Roberts A, Lawn R, Sumner J, Haneuse S, Liang L, Kubzansky L, Koenen K, Chibnik L. Posttraumatic stress disorder and epigenetic signatures of inflammation in middle-aged women. Psychoneuroendocrinology 2025, 182: 107654. PMID: 41135353, PMCID: PMC12720495, DOI: 10.1016/j.psyneuen.2025.107654.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderPost-traumatic stress disorder symptom severitySymptom severityAssociated with higher levelsNurses' Health Study IIStress disorderMeasures of post-traumatic stress disorderPost-traumatic stress disorder diagnosisConsistency of associationsWhite blood cell proportionsCross-sectional studyLifetime PTSD diagnosisPosttraumatic stress disorderWeak positive associationTime of blood drawMiddle-aged womenMeasurement of plasma C-reactive proteinSociodemographic factorsPlasma C-reactive proteinLinear mixed-effects modelsC-reactive proteinPTSD diagnosisTrauma exposureMixed-effects modelsStudy IIEstimating the associations between women’s maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy
Wu B, Vyas C, Medina A, Slopen N, Mahalingaiah S, Chavarro J, Mukherjee R, Weisskopf M, Roberts A. Estimating the associations between women’s maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy. PLOS ONE 2025, 20: e0331905. PMID: 40920854, PMCID: PMC12416833, DOI: 10.1371/journal.pone.0331905.Peer-Reviewed Original ResearchConceptsTumor necrosis factor alpha receptor 2Associated with higher riskC-reactive proteinAdverse neurodevelopmentInflammatory biomarkersNurses' Health Study 3Risk of adverse neurodevelopmentInterleukin-6Gestational risk factorsMaternal childhood abuseMaternal childhood maltreatmentGeneralized Estimating EquationsSample of well-educatedChronic systemic inflammationInflammatory biomarker levelsChildhood maltreatmentNon-HispanicExposure to maltreatmentPregnant participantsVulnerable populationsOffspring neurodevelopmentSystemic inflammationIFN-gProspective cohortInterferon-gamma