Alisson Clemenceau, BSc, MSc, PhD
she/her/hers
Postdoctoral AssociateAbout
Research
Publications
2026
Clinical and prognostic significance of parathyroid hormone-related protein in breast cancer: a systematic review and meta-analyses of observational studies in women
Clemenceau A, Bherer J, Grimshaw A, Durocher F, Diorio C, Wysolmerski J. Clinical and prognostic significance of parathyroid hormone-related protein in breast cancer: a systematic review and meta-analyses of observational studies in women. Endocrine Related Cancer 2026, 33: e250324. PMID: 41700599, PMCID: PMC12978662, DOI: 10.1530/erc-25-0324.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsparathyroid hormone-related proteinhormone-related proteinrisk of biasbreast cancerprognostic significancepositive progesterone receptor statusmeta-analyses of observational studiesbreast cancer susceptibility locipresence of bone metastasesdiagnosis of hypercalcemia of malignancymeta-analysesprogesterone receptor statuscancer susceptibility locibreast cancer biologynormal breast epithelial cellshypercalcemia of malignancylymph node invasionbreast cancer prognosisquantitative synthesisbreast epithelial cellssynthesis of outcomespresence of microcalcificationsstudy of womenreceptor statustumor characteristics
2024
Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring
Correa Pinto Junior D, Canal Delgado I, Yang H, Clemenceau A, Corvelo A, Narzisi G, Musunuri R, Meyer Berger J, Hendricks L, Tokumura K, Luo N, Li H, Oury F, Ducy P, Yadav V, Li X, Karsenty G. Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring. EMBO Reports 2024, 25: 12. PMID: 38228788, PMCID: PMC10897216, DOI: 10.1038/s44319-023-00031-3.Peer-Reviewed Original ResearchConceptsorganismal homeostasisadult offspringprogram of gene expressionadult miceembryonic originfunction of osteocalcinoffspring of mothersgene expressiongenetic backgroundadrenal steroidogenesismolecular underpinningsphysiological functionstestisglucose homeostasissynergistic regulationhomeostasisosteocalcinadult mammalscell proliferation
2023
Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness
Clemenceau A, Lacouture A, Bherer J, Ouellette G, Michaud A, Audet-Walsh É, Diorio C, Durocher F. Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness. Cancers 2023, 15: 2251. PMID: 37190179, PMCID: PMC10136791, DOI: 10.3390/cancers15082251.Peer-Reviewed Original Researchbreast carcinogenesisbreast cancer aggressivenessbreast cancer cell linescell linesbreast cancer progressioncultured ex vivopresence of estradiolpresence of microcalcificationslobular involutioncancer cell linesluminal phenotypecancer aggressivenessE2 treatmentmammary epithelial cellsnulliparous micetumor propertiesepithelial cellsproperties in vitrocontinuum of riskcancer progressionHuman Transcriptome Array
2022
Association between vitamin D and calcium intakes, breast microcalcifications, breast tissue age-related lobular involution and breast density
Clemenceau A, Chang S, Hanna M, Durocher F, Diorio C. Association between vitamin D and calcium intakes, breast microcalcifications, breast tissue age-related lobular involution and breast density. Menopause The Journal Of The North American Menopause Society 2022, 29: 1404-1415. PMID: 36219808, DOI: 10.1097/gme.0000000000002070.Peer-Reviewed Original Research
2021
TBC1D9: An Important Modulator of Tumorigenesis in Breast Cancer
Kothari C, Clemenceau A, Ouellette G, Ennour-Idrissi K, Michaud A, C.-Gaudreault R, Diorio C, Durocher F. TBC1D9: An Important Modulator of Tumorigenesis in Breast Cancer. Cancers 2021, 13: 3557. PMID: 34298771, PMCID: PMC8304074, DOI: 10.3390/cancers13143557.Peer-Reviewed Original ResearchIs Carboxypeptidase B1 a Prognostic Marker for Ductal Carcinoma In Situ?
Kothari C, Clemenceau A, Ouellette G, Ennour-Idrissi K, Michaud A, Diorio C, Durocher F. Is Carboxypeptidase B1 a Prognostic Marker for Ductal Carcinoma In Situ? Cancers 2021, 13: 1726. PMID: 33917306, PMCID: PMC8038727, DOI: 10.3390/cancers13071726.Peer-Reviewed Original Researchductal carcinoma in situinvasive ductal carcinomaatypical ductal hyperplasiacarcinoma in situbreast tissue samplesDCIS cell lineslow-grade ductal carcinoma in situtissue samplescell line modelshuman transcriptome dataductal carcinomaunnecessary surgeryductal hyperplasiasurvival outcomesprognostic markergene signaturemRNA levelsSPP1</i>cell linesBC progressionquantitative PCR
2020
Breast Cancer and Microcalcifications: An Osteoimmunological Disorder?
Clemenceau A, Michou L, Diorio C, Durocher F. Breast Cancer and Microcalcifications: An Osteoimmunological Disorder? International Journal Of Molecular Sciences 2020, 21: 8613. PMID: 33203195, PMCID: PMC7696282, DOI: 10.3390/ijms21228613.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptspro-inflammatory cytokinesbreast cancerrheumatoid arthritisbiological agentsbreast cancer incidencepresence of microcalcificationscancer cell line proliferationosteoclast-like cellsanabolic drugsbreast carcinogenesiscell line proliferationxenograft micecancer incidencebreast tissuebreastin vivoin vitroosteoblast-likemigratory abilitycytokineswomencancerSecreted Frizzled-Related Protein 1 as a Biomarker against Incomplete Age-Related Lobular Involution and Microcalcifications’ Development
Clemenceau A, Hanna M, Ennour-Idrissi K, Burguin A, Diorio C, Durocher F. Secreted Frizzled-Related Protein 1 as a Biomarker against Incomplete Age-Related Lobular Involution and Microcalcifications’ Development. Cancers 2020, 12: 2693. PMID: 32967276, PMCID: PMC7565692, DOI: 10.3390/cancers12092693.Peer-Reviewed Original ResearchRole of Secreted Frizzled-Related Protein 1 in Early Mammary Gland Tumorigenesis and Its Regulation in Breast Microenvironment
Clemenceau A, Diorio C, Durocher F. Role of Secreted Frizzled-Related Protein 1 in Early Mammary Gland Tumorigenesis and Its Regulation in Breast Microenvironment. Cells 2020, 9: 208. PMID: 31947616, PMCID: PMC7017175, DOI: 10.3390/cells9010208.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2019
Early-onset emphysema in a large French-Canadian family: a genetic investigation
Bossé Y, Lamontagne M, Gaudreault N, Racine C, Levesque M, Smith B, Auger D, Clemenceau A, Paré M, Laviolette L, Tremblay V, Maranda B, Morissette M, Maltais F. Early-onset emphysema in a large French-Canadian family: a genetic investigation. The Lancet Respiratory Medicine 2019, 7: 427-436. PMID: 31000475, DOI: 10.1016/s2213-2600(19)30056-6.Peer-Reviewed Original ResearchConceptswhole-exome sequencingnegative regulatorSHP-1biologically relevant genesnon-synonymous variantsloss-of-function effectprotein expressionearly-onset emphysemaprotein functionunrelated individualsrelevant genesinherited mutationsincomplete penetrancegenetic investigationsactivity in vitrofamily membersmutationsCanadian Institutesprotein
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