Giulia Lorenzon, MSc, PhD
Postdoctoral AssociateDownloadHi-Res Photo
About
Copy Link
Titles
Postdoctoral Associate
Appointments
Education & Training
- PhD
- Karolinska Institutet, Medical Sciences (2024)
- MSc
- Donders Institute for Brain, Cognition and Behaviour, Cognitive Neuroscience - Plasticity and Memory
- MSc
- University of Padua, Psychobiology and Cognitive Psychology
Research
Copy Link
Overview
Dr. Lorenzon is a postdoctoral researcher investigating sex-specific vulnerabilities in brain health and Alzheimer’s disease. Her work focuses on how reproductive lifespan factors and hormonal exposures shape functional brain connectivity across the female lifespan, particularly during the menopausal transition, and how these processes relate to brain pathology and cognitive decline.
Building on her PhD at Karolinska Institutet, where she investigated heterogeneity in aging and Alzheimer’s disease using MRI biomarkers, her current work integrates multimodal neuroimaging, plasma biomarkers, and detailed clinical phenotyping in longitudinal cohorts of amnestic and non-amnestic Alzheimer’s disease.
She is also interested in brain–body interactions, including the role of stress and psychosomatic mechanisms.
Medical Research Interests
Brain; Default Mode Network; Dementia; Hormone Replacement Therapy; Hormones; Implementation Science; Magnetic Resonance Imaging; Precision Medicine; Reproductive Health; Trauma and Stressor Related Disorders
Public Health Interests
Biomarkers; Mental Health; Network Analysis; Reproduction; Women's Health; Aging
ORCID
0009-0004-1562-9677
Research at a Glance
Publications Timeline
A big-picture view of Giulia Lorenzon's research output by year.
Research Interests
Research topics Giulia Lorenzon is interested in exploring.
8Publications
38Citations
Magnetic Resonance Imaging
Brain
Publications
2025
Imaging Heterogeneity in Atypical AD
Mohanty R, Wheatley S, Lorenzon G, Poulakis K, Inguanzo A, Westman E. Imaging Heterogeneity in Atypical AD. Alzheimer's & Dementia 2025, 21: e099056. PMCID: PMC12737898, DOI: 10.1002/alz70856_099056.Peer-Reviewed Original ResearchConceptsAtrophy subtypesAD subtypesAlzheimer's diseaseTau-PETNeurobiological heterogeneityWhite matter abnormalitiesDonepezil treatmentAtypical ADCognitive declineHippocampal atrophyNeuroimaging modalitiesPersonalized diagnosisHypometabolismResponse to treatmentTypicTau pathologySeverityMinimal atrophySubtypesFDG-PETTauHippocampalNeuroimagingA-synucleinDonepezilRisk and protective factors associated with brain grey matter patterns in a population-based cohort of cognitively unimpaired 70 years old
Lorenzon G, Marseglia A, Poulakis K, Imbimbo C, Rydén L, Galaris E, Lindberg O, Shams S, Mohanty R, Ferreira D, Kivipelto M, Eriksdotter M, Kern S, Skoog I, Westman E. Risk and protective factors associated with brain grey matter patterns in a population-based cohort of cognitively unimpaired 70 years old. BMC Medicine 2025, 24: 39. PMID: 41408633, PMCID: PMC12822138, DOI: 10.1186/s12916-025-04583-0.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsGray matterMRI measures of cortical thicknessCognitively unimpaired older adultsGM patternsMeasures of cortical thicknessPoorer episodic memoryGray matter patternBrain gray matterMRI measurementsAt-risk alcohol consumptionCognitive profileEpisodic memoryBrain trajectoriesHigher oddsSubcortical volumesVisuospatial abilityDementia-related changesOdds of heart diseaseGM lossGM integrityFrontoparietal regionsBrain healthLongitudinal declineWhite matter hyperintensity volumeLate lifeBrain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention
Lorenzon G, Marseglia A, Mohanty R, Lehtisalo J, Poulakis K, Ngandu T, Solomon A, Kivipelto M, Westman E. Brain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention. The Journal Of Prevention Of Alzheimer's Disease 2025, 12: 100390. PMID: 40998691, PMCID: PMC12627893, DOI: 10.1016/j.tjpad.2025.100390.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMultimodal lifestyle interventionAt-risk individualsLifestyle interventionFINGER interventionPrevention strategiesDementia prevention strategiesVascular risk managementMultidomain lifestyle interventionEffective primary prevention strategyLifestyle intervention groupRisk factorsPrimary prevention strategiesModifiable risk factorsCognitive benefitsAt-risk populationsPhysical activityLifestyle ProfileCognitive performanceMRI-based cortical thicknessPost-interventionIntervention groupPre-interventionLifestyle factorsPopulation-basedHealth advice
2024
Frontoparietal atrophy trajectories in cognitively unimpaired elderly individuals using longitudinal Bayesian clustering
Lorenzon G, Poulakis K, Mohanty R, Kivipelto M, Eriksdotter M, Ferreira D, Westman E, Initiative F. Frontoparietal atrophy trajectories in cognitively unimpaired elderly individuals using longitudinal Bayesian clustering. Computers In Biology And Medicine 2024, 182: 109190. PMID: 39357135, DOI: 10.1016/j.compbiomed.2024.109190.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCognitively unimpaired individualsUnimpaired individualsCognitively unimpaired elderly individualsStructural magnetic resonance imagingParietal brain regionsMagnetic resonance imagingCognitive profileBrain regionsParietal atrophyCognitive declineIdentification of at-risk individualsAt-risk individualsCerebrovascular burdenLongitudinal trajectoriesGM patternsCognitionMatter profileResonance imagingIndividualsTheory of agingElderly individualsAgeDistinct patterns of atrophy and their determinants among the elderly population: insights from the Gothenburg H70–1944 Birth cohort
Lorenzon G, Marseglia A, Poulakis K, Muehlboeck S, Ferreira D, Kivipelto M, Zettergren A, Skoog I, Westman E. Distinct patterns of atrophy and their determinants among the elderly population: insights from the Gothenburg H70–1944 Birth cohort. Cerebral Circulation - Cognition And Behavior 2024, 6: 100246. DOI: 10.1016/j.cccb.2024.100246.Peer-Reviewed Original ResearchConceptsVascular risk factorsPatterns of brain atrophyBirth cohortRisk factorsPatterns of atrophyPeople at-riskCross-sectional studyMultinomial logistic regression modelLogistic regression modelsSmall vessel diseaseCognitively intact older individualsCardiometabolic conditionsPatterns of gray matter atrophyBrain atrophyNon-clinical populationsGray matter volumeGray matter atrophyVessel diseaseMedical conditionsOlder individualsElderly individualsReference groupParietal-occipital regionsElderly populationCardiometabolic disorders
2023
Correction: Differential response to donepezil in MRI subtypes of mild cognitive impairment
Diaz‑Galvan P, Lorenzon G, Mohanty R, Mårtensson G, Cavedo E, Lista S, Vergallo A, Kantarci K, Hampel H, Dubois B, Grothe M, Ferreira D, Westman E. Correction: Differential response to donepezil in MRI subtypes of mild cognitive impairment. Alzheimer's Research & Therapy 2023, 15: 177. PMID: 37838742, PMCID: PMC10576352, DOI: 10.1186/s13195-023-01320-8.Peer-Reviewed Original ResearchCitationsAltmetricDifferential response to donepezil in MRI subtypes of mild cognitive impairment
Diaz-Galvan P, Lorenzon G, Mohanty R, Mårtensson G, Cavedo E, Lista S, Vergallo A, Kantarci K, Hampel H, Dubois B, Grothe M, Ferreira D, Westman E. Differential response to donepezil in MRI subtypes of mild cognitive impairment. Alzheimer's Research & Therapy 2023, 15: 117. PMID: 37353809, PMCID: PMC10288762, DOI: 10.1186/s13195-023-01253-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsResponse to donepezilSubtyping approachMCI individualsHippocampal-sparingMagnetic resonance imagingTotal gray matter volumeCategorical approachSubtypes of mild cognitive impairmentGray matter volumeAlzheimer's diseaseStructural MRI dataPathophysiological heterogeneityFollow-up assessmentPatterns of atrophyAnnual percentage changeMild cognitive impairmentMatter volumeMinimal atrophyLimbic-predominantClinical trialsClinical follow-up assessmentCognitive impairmentAtrophy subtypesTreatment of Alzheimer's diseaseResponse to treatment
2022
Heterogeneity in normal aging: longitudinal trajectories of grey matter
Lorenzon G, Poulakis K, Mohanty R, Kivipelto M, Eriksdotter M, Ferreira D, Westman E. Heterogeneity in normal aging: longitudinal trajectories of grey matter. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.063162.Peer-Reviewed Original ResearchCitationsConceptsLongitudinal trajectoriesBrain changesNormal agingOvert cognitive impairmentHealthy agingBrain resistanceCognitive profileCognitive resilienceWhite matter profilesCortical volumeCognitive impairmentCognitive declineEnvironmental protective factorsGray matterProtective factorsBrainMixed effects modelsDementia researchIndividual trajectoriesExploratory studyImpairmentLongitudinal clustering
Get In Touch
Copy Link
Contacts
Locations
CNIC
Lab
Boardman Building
330 Cedar Street, Fl 6th
New Haven, CT 06510