Brainwaves
Yale School of Medicine Department of Neurology
New Faculty Spotlight: Lee Schwamm, MD
Associate Dean, Digital Strategy & Transformation, Office of the Dean, YSM; Professor in Biomedical Informatics & Data Sciences, YSM; Professor of Neurology, YSM; Senior Vice President & Chief Digital Health Officer, YNHHS
Dr. Lee H. Schwamm, MD is Associate Dean for Digital Strategy and Transformation for Yale School of Medicine, and Senior Vice President + Chief Digital Health Officer for Yale New Haven Health System. In this role, he is leading the development of a new digital health strategy for the school and the health system, and serves as an influential physician leader and an agent of change to catalyze the equitable adoption of virtual care and digital enablement throughout the enterprise.
Before joining Yale, Dr. Schwamm spent 3 decades of service at the Mass General Brigham Health System in academic and administrative leadership roles. He was the inaugural C. Miller Fisher Chair in Vascular Neurology, Executive Vice Chair of Neurology and Director of the Center for TeleHealth at Massachusetts General Hospital; Vice President for Digital Patient Experience and Virtual Care, and Chief Digital Advisor for the Mass General Brigham Health System, and a Professor of Neurology at Harvard Medical School. He oversaw all systemwide virtual care and telehealth activities including synchronous and synchronous virtual visits and consults, remote patient monitoring, virtual urgent care and online second opinions. During the first 6 months of COVID, he led adoption efforts for 10,000 clinicians to provide over 1.7 M virtual visits, and introduced a suite of innovative inpatient virtual solutions.
A graduate of both Harvard College and Harvard Medical School, he completed residency training in neurology, and fellowship training in stroke and neurocritical care, all at Massachusetts General Hospital where he subsequently joined the faculty in 1996. He has spent the past 2 decades in telehealth, as a pioneer in telestroke and a leading advocate and policy advisor for the American Heart Association. He is a an internationally recognized expert in stroke diagnosis, treatment and prevention and a Fellow of the American Heart Association, American Academy of Neurology and the American Neurological Association. His research has been funded by many organizations including the NIH, AHA, PCORI, AHRQ, HRSA, CDC, and others, and he is the author of >500 peer-reviewed articles and chaired many of the current practice guidelines for stroke and telehealth-enabled care delivery. Under his leadership, the AHA Get with the Guidelines–Stroke Registry has grown into the world’s largest stroke registry with over 8M patient encounters; it has changed stroke practice at hospitals across the US, and set a global standard for stroke care. He has received numerous awards for innovation, leadership, and advocacy in the field of stroke and digital health, and held many senior leadership positions within the AHA, including service on their National Board of Directors. He has served on multiple editorial boards, including the digital health section editor for Stroke, and the international advisory board for Lancet Digital Health.
New Faculty Spotlight: Clemens Scherzer, MD
"I am coming to Yale School of Medicine from Harvard Medical School and Brigham and Women’s Hospital in Boston to build a transformative Center for Precision Neurology focused on Parkinson’s disease and related brain diseases. I am excited to launch the new Stephen and Denise Adams Center for Parkinson’s Research at YSM as inaugural director and to serve as the academic chief of the movement disorders division and Stephen and Denise Adams Professor of Neurology.
My dream is to develop a healthcare of the future for Parkinson’s disease that is predictive and precise: a future, where we will forecast a patient’s disease progression using predictive analytics and where we will prevent disabling complications from ever occurring by intervening ahead of time with targeted therapeutics. In order to identify genetic drivers, precision therapeutics and tailored biomarkers, we are systematically mapping the DNA and RNA software of 1 million brain cells and thousands of patients.
I am a mountain man, raised in the Alps and Dolomites. When the mountains are calling, my family loves to answer and hopes to summit forty 4,000-footers in the White Mountains over the coming years."
New Faculty Spotlight: Srikant Rangaraju, MBBS, MS
"I am very excited to be a part of the Department of Neurology at YSM!
I completed my neurology residency at Emory University and my vascular neurology fellowship at the University of Pittsburgh Medical Center, and I then joined the faculty in the Department of Neurology at Emory University in 2014. I established my research laboratory at Emory in 2015.
Our research has focused on exploring immune-mediated mechanisms of neurodegeneration and post-ischemic injury in the brain, leveraging pre-clinical mouse models, as well as multi-omics modalities to assess molecular changes occurring in diverse classes of neurons and glial cells. We have identified promising targets to modulate microglia-mediated mechanisms in neurodegeneration and stroke, as well as developed novel in vivo labeling tools to assess protein-level (proteomic) mechanisms of disease that are unique to different brain cell types. We have an emerging interest in proteomics-based discovery of plasma biomarkers in ischemic stroke.
On the clinical front, I am a stroke/vascular neurologist, and look forward to providing patient care in in-patient and clinic-based settings. I am passionate about mentoring clinical and non-clinical trainees at all levels.
As a two-career physician-scientist couple, my wife and I were seeking opportunities for growth on the professional and personal fronts. The Department of Neurology at YSM seemed to be the right fit for the next phase for me and for my research program, via a diverse, multi-disciplinary, supportive and collaborative research environment at Yale. The fit also seemed right for my wife, Nitya Bakshi, MD, who will be joining the Department of Pediatrics (Division Hematology/Oncology) at YSM and growing her research program on chronic pain in children and adolescents with sickle cell disease.
My family and I are excited to make YSM and the New Haven area our new home. We have two children (Nandini: eight years old, and Siddharth: three years old). I play the guitar, am currently learning how to play the drums, and am an avid Foo Fighters fan."
Yale Neurology 70th Anniversary Celebration
Yale's Department of Neurology celebrated its 70th year with a celebration at the Quin House in Boston, Massachusetts as part of the American Academy of Neurology (AAN) meeting.
Shown from left to right: Orly Avitzur, MD, MBA, president of the AAN, who welcomed the group ; Richard Mattson, MD, professor of neurology who provided a history of the department; David Hafler, MD, current chair; and Stephen Waxman, MD, PhD, former department chair. Drs. Waxman and Hafler gave perspectives on the Department.
News
- Could transcranial stimulation reduce brain damage after a stroke?Source: Medical News Today
- Raising Awareness for World Multiple Sclerosis DaySource: NBC Connecticut
- How Epilepsy Surgery Is Curing More SeizuresSource: Yale Medicine
- 2023 ‘Top Doctors’ List Features Over 250 Yale Medicine PhysiciansSource: Yale Medicine
- A Staring SpellSource: Yale Scientific
Publications
- Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome TrialsBalasubramanian P, Kernan W, Sheth K, Ofstad A, Rosenstock J, Wanner C, Zinman B, Mattheus M, Marx N, Inzucchi S. Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome Trials. Stroke 2023, 54: 2013-2021. PMID: 37449424, PMCID: PMC10358436, DOI: 10.1161/strokeaha.122.042053.
- Repeated intravenous infusion of mesenchymal stem cells enhances recovery of motor function in a rat model with chronic spinal cord injuryKurihara K, Sasaki M, Nagahama H, Obara H, Fukushi R, Hirota R, Yoshimoto M, Teramoto A, Kocsis J, Yamashita T, Honmou O. Repeated intravenous infusion of mesenchymal stem cells enhances recovery of motor function in a rat model with chronic spinal cord injury. Brain Research 2023, 1817: 148484. PMID: 37442249, DOI: 10.1016/j.brainres.2023.148484.
- Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injuryTerada K, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Oka S, Ukai R, Yokoyama T, Iizuka Y, Sakai T, Fukumura S, Tsugawa T, Kocsis J, Honmou O. Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury. Pediatric Research 2023, 94: 1921-1928. PMID: 37422495, DOI: 10.1038/s41390-023-02717-9.
- Origin and development of the claustrum in rhesus macaqueLi H, Duque A, Rakic P. Origin and development of the claustrum in rhesus macaque. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2220918120. PMID: 37406098, PMCID: PMC10334778, DOI: 10.1073/pnas.2220918120.
- CT With CTA Versus MRI in Patients Presenting to the Emergency Department With Dizziness: Analysis Using Propensity Score Matching.Tu L, Navaratnam D, Melnick E, Forman H, Venkatesh A, Malhotra A, Yaesoubi R, Sureshanand S, Sheth K, Mahajan A. CT With CTA Versus MRI in Patients Presenting to the Emergency Department With Dizziness: Analysis Using Propensity Score Matching. American Journal Of Roentgenology 2023, 221: 836-845. PMID: 37404082, DOI: 10.2214/ajr.23.29617.
- Rethinking our Approach to Educating New Learners in Movement Disorders Phenomenological DiagnosisSchaefer S. Rethinking our Approach to Educating New Learners in Movement Disorders Phenomenological Diagnosis. Movement Disorders 2023, 38: 1379-1383. PMID: 37403965, DOI: 10.1002/mds.29530.
- Mapping Lesion-Related Epilepsy to a Human Brain NetworkSchaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology 2023, 80: 891-902. PMID: 37399040, PMCID: PMC10318550, DOI: 10.1001/jamaneurol.2023.1988.
- Relationships of in vivo brain norepinephrine transporter and age, BMI, and genderKoohsari S, Sadabad F, Pittman B, Gallezot J, Carson R, van Dyck C, Li C, Potenza M, Matuskey D. Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender. Synapse 2023, 77: e22279. PMID: 37382240, PMCID: PMC10416616, DOI: 10.1002/syn.22279.
- Case report: Psychedelic-induced seizures captured by intracranial electrocorticographyBlond B, Schindler E. Case report: Psychedelic-induced seizures captured by intracranial electrocorticography. Frontiers In Neurology 2023, 14: 1214969. PMID: 37456653, PMCID: PMC10343433, DOI: 10.3389/fneur.2023.1214969.
- TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS InjuryShafit-Zagardo B, Sidoli S, Goldman J, DuBois J, Corboy J, Strittmatter S, Guzik H, Edema U, Arackal A, Botbol Y, Merheb E, Nagra R, Graff S. TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury. Cells 2023, 12: 1734. PMID: 37443768, PMCID: PMC10340176, DOI: 10.3390/cells12131734.
- Improvement in the Prediction of Cerebrovascular Events With White Matter Hyperintensityde Havenon A, Smith E, Sharma R, Falcone G, Bangad A, Prabhakaran S, Sheth K. Improvement in the Prediction of Cerebrovascular Events With White Matter Hyperintensity. Journal Of The American Heart Association 2023, 12: e029374. PMID: 37345754, PMCID: PMC10356061, DOI: 10.1161/jaha.123.029374.
- Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathologyPham M, Masi G, Patzina R, Obaid A, Oxendine S, Oh S, Payne A, Nowak R, O’Connor K. Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathology. Acta Neuropathologica 2023, 146: 319-336. PMID: 37344701, PMCID: PMC11380498, DOI: 10.1007/s00401-023-02603-y.
- Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic StrokeMac Grory B, Holmes D, Matsouaka R, Shah S, Chang C, Rison R, Jindal J, Holmstedt C, Logan W, Corral C, Mackey J, Gee J, Bonovich D, Walker J, Gropen T, Benesch C, Dissin J, Pandey H, Wang D, Unverdorben M, Hernandez A, Reeves M, Smith E, Schwamm L, Bhatt D, Saver J, Fonarow G, Peterson E, Xian Y. Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke. JAMA 2023, 329: 2038-2049. PMID: 37338878, PMCID: PMC10282891, DOI: 10.1001/jama.2023.8073.
- Outcomes of recurrent stroke in patients with atrial fibrillation according to presumed etiologyPedreira B, Zachrison K, Singhal A, Yan Z, Oliveira-Filho J, Schwamm L. Outcomes of recurrent stroke in patients with atrial fibrillation according to presumed etiology. Arquivos De Neuro-Psiquiatria 2023, 81: 616-623. PMID: 37336506, PMCID: PMC10371407, DOI: 10.1055/s-0043-1769124.
- A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depressionJauhar S, Arnone D, Baldwin D, Bloomfield M, Browning M, Cleare A, Corlett P, Deakin J, Erritzoe D, Fu C, Fusar-Poli P, Goodwin G, Hayes J, Howard R, Howes O, Juruena M, Lam R, Lawrie S, McAllister-Williams H, Marwaha S, Matuskey D, McCutcheon R, Nutt D, Pariante C, Pillinger T, Radhakrishnan R, Rucker J, Selvaraj S, Stokes P, Upthegrove R, Yalin N, Yatham L, Young A, Zahn R, Cowen P. A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression. Molecular Psychiatry 2023, 28: 3149-3152. PMID: 37322065, PMCID: PMC10618084, DOI: 10.1038/s41380-023-02095-y.
- Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions.Hong C, Lamsam L, Yadlapalli V, Parasuram N, Mazurek M, Chavva I, Lalwani D, Zabinska J, Schiff S, Manes R, Vining E, Rimmer R, Kimberly W, Sheth K, Omay S. Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions. Journal Of Neurosurgery 2023, 139: 1664-1670. PMID: 37347618, DOI: 10.3171/2023.5.jns23174.
- Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in ratNakazaki M, Lankford K, Yamamoto H, Mae Y, Kocsis J. Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat. Clinical And Translational Medicine 2023, 13: e1284. PMID: 37323108, PMCID: PMC10272923, DOI: 10.1002/ctm2.1284.
- CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastomaGeraldo L, Garcia C, Xu Y, Leser F, Grimaldi I, de Camargo Magalhães E, Dejaegher J, Solie L, Pereira C, Correia A, De Vleeschouwer S, Tavitian B, Canedo N, Mathivet T, Thomas J, Eichmann A, Lima F. CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma. Cellular And Molecular Life Sciences 2023, 80: 179. PMID: 37314567, PMCID: PMC10267017, DOI: 10.1007/s00018-023-04788-7.
- Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine ProtectionKim D, Biancon G, Bai Z, VanOudenhove J, Liu Y, Kothari S, Gowda L, Kwan J, Buitrago‐Pocasangre N, Lele N, Asashima H, Racke M, Wilson J, Givens T, Tomayko M, Schulz W, Longbrake E, Hafler D, Halene S, Fan R. Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine Protection. Small Methods 2023, 7: e2300594. PMID: 37312418, PMCID: PMC10592458, DOI: 10.1002/smtd.202300594.
- Three-dimensional imaging of vascular development in the mouse epididymis.Damon-Soubeyrand C, Bongiovanni A, Chorfa A, Goubely C, Pirot N, Pardanaud L, Piboin-Fragner L, Vachias C, Bravard S, Guiton R, Thomas J, Saez F, Kocer A, Tardivel M, Drevet J, Henry-Berger J. Three-dimensional imaging of vascular development in the mouse epididymis. ELife 2023, 12 PMID: 37310207, PMCID: PMC10264076, DOI: 10.7554/elife.82748.
- Polygenic Susceptibility to Hypertension and Cognitive Performance in Middle-aged Persons Without Stroke or DementiaRivier C, Szejko N, Renedo D, Noche R, Acosta J, Both C, Sharma R, Torres-Lopez V, Payabvash S, de Havenon A, Sheth K, Gill T, Falcone G. Polygenic Susceptibility to Hypertension and Cognitive Performance in Middle-aged Persons Without Stroke or Dementia. Neurology 2023, 101: e512-e521. PMID: 37295956, PMCID: PMC10401683, DOI: 10.1212/wnl.0000000000207427.
- MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicityYandamuri S, Filipek B, Obaid A, Lele N, Thurman J, Makhani N, Nowak R, Guo Y, Lucchinetti C, Flanagan E, Longbrake E, O’Connor K. MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity. JCI Insight 2023, 8: e165373. PMID: 37097758, PMCID: PMC10393237, DOI: 10.1172/jci.insight.165373.
- Mechanistic Implications of Cortical Superficial Siderosis in Patients With Mixed Location Intracerebral Hemorrhage and Cerebral MicrobleedsDas A, Gokcal E, Biffi A, Regenhardt R, Pasi M, Abramovitz Fouks A, Viswanathan A, Goldstein J, Schwamm L, Rosand J, Greenberg S, Gurol M. Mechanistic Implications of Cortical Superficial Siderosis in Patients With Mixed Location Intracerebral Hemorrhage and Cerebral Microbleeds. Neurology 2023, 101: e636-e644. PMID: 37290968, PMCID: PMC10424843, DOI: 10.1212/wnl.0000000000207476.
- The clinical and genomic features of seizures in meningiomasDincer A, Jalal M, Gupte T, Vetsa S, Vasandani S, Yalcin K, Marianayagam N, Blondin N, Corbin Z, McGuone D, Fulbright R, Erson-Omay Z, Günel M, Moliterno J. The clinical and genomic features of seizures in meningiomas. Neuro-Oncology Advances 2023, 5: i49-i57. PMID: 37287582, PMCID: PMC10243847, DOI: 10.1093/noajnl/vdac110.
- Principal component analysis of synaptic density measured with [11C]UCB-J PET in early Alzheimer’s diseaseO'Dell R, Higgins-Chen A, Gupta D, Chen M, Naganawa M, Toyonaga T, Lu Y, Ni G, Chupak A, Zhao W, Salardini E, Nabulsi N, Huang Y, Arnsten A, Carson R, van Dyck C, Mecca A. Principal component analysis of synaptic density measured with [11C]UCB-J PET in early Alzheimer’s disease. NeuroImage Clinical 2023, 39: 103457. PMID: 37422964, PMCID: PMC10338149, DOI: 10.1016/j.nicl.2023.103457.
- Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDCLocke S, O’Bryan J, Zubair A, Rethana M, Moffarah A, Krause P, Farhadian S. Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2023, 29: 1127-1135. PMID: 37209667, PMCID: PMC10202888, DOI: 10.3201/eid2906.221890.
- Effectiveness of a Quality Improvement Intervention on Reperfusion Treatment for Patients With Acute Ischemic StrokeWang C, Gu H, Zong L, Zhang X, Zhou Q, Jiang Y, Li H, Meng X, Yang X, Wang M, Huo X, Wangqin R, Bei Y, Qi X, Liu X, Hu S, Wang Z, Zhao X, Wang Y, Liu L, Ma X, Morgan L, Xian Y, Schwamm L, Wang Y, Li Z, Yang Q, Chen G, Ma Q, Li X, Chen J, Zhao X, Wang H, Niu X, Xu J, Zhao L, Wang Z, Huang D, Jin X, Chen S, Li J, Yu J, Liu P, Li G, Hao Y, Yang G, Huang X, Zhou C, Yang J, Gu J, Sun P, Guo Z, Ma G, Chen G, Tang M, Wang N, Chen L, Li J, Li A, Li S, Cao M, Guo J, Ren Y, Li T, Zhang L, Xie Z, Dong J, Kong X, Liang H, Zhang Y. Effectiveness of a Quality Improvement Intervention on Reperfusion Treatment for Patients With Acute Ischemic Stroke. JAMA Network Open 2023, 6: e2316465. PMID: 37266940, PMCID: PMC10238948, DOI: 10.1001/jamanetworkopen.2023.16465.
- Twenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Statusde Havenon A, Zhou L, Johnston K, Dangayach N, Ney J, Yaghi S, Sharma R, Abbasi M, Delic A, Majersik J, Anadani M, Tirschwell D, Sheth K. Twenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Status. Neurology 2023, 101: e464-e474. PMID: 37258298, PMCID: PMC10401675, DOI: 10.1212/wnl.0000000000207446.
- Intracranial Entrainment Reveals Statistical Learning across Levels of AbstractionSherman B, Aljishi A, Graves K, Quraishi I, Sivaraju A, Damisah E, Turk-Browne N. Intracranial Entrainment Reveals Statistical Learning across Levels of Abstraction. Journal Of Cognitive Neuroscience 2023, 35: 1312-1328. PMID: 37262357, DOI: 10.1162/jocn_a_02012.
- Timing and Predictors of Recanalization After Anticoagulation in Cerebral Venous ThrombosisOmran S, Shu L, Chang A, Parikh N, Zubair A, Simpkins A, Heldner M, Hakim A, Al Kasab S, Nguyen T, Klein P, Goldstein E, Vedovati M, Paciaroni M, Liebeskind D, Yaghi S, Cutting S. Timing and Predictors of Recanalization After Anticoagulation in Cerebral Venous Thrombosis. Journal Of Stroke 2023, 25: 291-298. PMID: 37282376, PMCID: PMC10250867, DOI: 10.5853/jos.2023.00213.
- Borderzone Infarcts and Recurrent Cerebrovascular Events in Symptomatic Intracranial Arterial Stenosis: A Systematic Review and Meta-AnalysisDas S, Shu L, Morgan R, Shah A, Fayad F, Goldstein E, Chahien D, Maglinger B, Bokka S, Owens C, Abbasi M, Kvernland A, Siegler J, Mac Grory B, Nguyen T, Furie K, Khatri P, Mistry E, Prabhakaran S, Liebeskind D, Romano J, de Havenon A, Palaiodimou L, Tsivgoulis G, Yaghi S. Borderzone Infarcts and Recurrent Cerebrovascular Events in Symptomatic Intracranial Arterial Stenosis: A Systematic Review and Meta-Analysis. Journal Of Stroke 2023, 25: 223-232. PMID: 37282372, PMCID: PMC10250880, DOI: 10.5853/jos.2023.00185.
- Rationale and design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III): a randomised, phase III, open-label, controlled trialXiong Y, Campbell B, Fisher M, Schwamm L, Parsons M, Li H, Pan Y, Meng X, Zhao X, Wang Y. Rationale and design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III): a randomised, phase III, open-label, controlled trial. Stroke And Vascular Neurology 2023, 9: 82-89. PMID: 37247876, PMCID: PMC10956103, DOI: 10.1136/svn-2023-002310.
- Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patientsDiray-Arce J, Fourati S, Jayavelu N, Patel R, Maguire C, Chang A, Dandekar R, Qi J, Lee B, van Zalm P, Schroeder A, Chen E, Konstorum A, Brito A, Gygi J, Kho A, Chen J, Pawar S, Gonzalez-Reiche A, Hoch A, Milliren C, Overton J, Westendorf K, Network I, Abraham J, Adkisson M, Albert M, Torres L, Alvarenga B, Anderson M, Anderson E, Arnett A, Asashima H, Atkinson M, Baden L, Barton B, Beach K, Beagle E, Becker P, Bell M, Bernui M, Bime C, Kumar A, Booth L, Borresen B, Brakenridge S, Bristow L, Bryant R, Calfee C, Manuel J, Carrillo S, Chak S, Chang I, Connors J, Conway M, Corry D, Cowan D, Croen B, Dela Cruz C, Cusimano G, Eaker L, Edwards C, Ehrlich L, Elashoff D, Erickson H, Erle D, Farhadian S, Farrugia K, Fatou B, Fernandes A, Fernandez-Sesma A, Fragiadakis G, Furukawa S, Geltman J, Ghale R, Bermúdez M, Goonewardene M, Sanchez E, Guirgis F, Hafler D, Hamilton S, Harris P, Nemati A, Hendrickson C, Agudelo N, Hodder T, Holland S, Hough C, Huerta C, Hurley K, Hutton S, Iwasaki A, Jauregui A, Jha M, Johnson B, Joyner D, Kangelaris K, Kelly G, Khalil Z, Khan Z, Kheradmand F, Kim J, Kimura H, Ko A, Kohr B, Kraft M, Krummel M, Kutzler M, Lasky-Su J, Lee S, Lee D, Leipold M, Lentucci C, Leroux C, Lin E, Liu S, Love C, Lu Z, Maliskova L, Roth B, Manohar M, Martens M, McComsey G, McEnaney K, McLin R, Melamed E, Melnyk N, Mendez K, Messer W, Metcalf J, Michelotti G, Mick E, Mohanty S, Mosier J, Mulder L, Murphy M, Nadeau K, Nelson E, Nelson A, Nguyen V, Oberhaus J, Panganiban B, Pellegrini K, Pickering H, Powell D, Presnell S, Pulendran B, Rahman A, Sadeed A, Raskin A, Reed E, Pereira S, Rivera A, Rogers J, Rogers A, Rogowski B, Rooks R, Rosenberg-Hasson Y, Rothman J, Rousseau J, Salehi-Rad R, Saluvan M, Samaha H, Schaenman J, Schunk R, Semenza N, Sen S, Sevransky J, Seyfert-Margolis V, Shaheen T, Shaw A, Sieg S, Siegel S, Sigal N, Siles N, Simmons B, Simon V, Singh G, Sinko L, Smith C, Smolen K, Song L, Srivastava K, Sullivan P, Syphurs C, Tcheou J, Tegos G, Tharp G, Ally A, Tsitsiklis A, Ungaro R, Vaysman T, Viode A, Vita R, Wang X, Ward A, Ward D, Willmore A, Woloszczuk K, Wong K, Woodruff P, Xu L, van Haren S, van de Guchte A, Zhao Y, Cairns C, Rouphael N, Bosinger S, Kim-Schulze S, Krammer F, Rosen L, Grubaugh N, van Bakel H, Wilson M, Rajan J, Steen H, Eckalbar W, Cotsapas C, Langelier C, Levy O, Altman M, Maecker H, Montgomery R, Haddad E, Sekaly R, Esserman D, Ozonoff A, Becker P, Augustine A, Guan L, Peters B, Kleinstein S. Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients. Cell Reports Medicine 2023, 4: 101079. PMID: 37327781, PMCID: PMC10203880, DOI: 10.1016/j.xcrm.2023.101079.
- Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imagingde Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.
- Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic AnalysesRenedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.
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- The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire PropertiesJiang R, Roy B, Wu Q, Mohanty S, Nowak R, Shaw A, Kleinstein S, O’Connor K. The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties. ImmunoHorizons 2023, 7: 310-322. PMID: 37171806, PMCID: PMC10579972, DOI: 10.4049/immunohorizons.2200078.
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- Association of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018Kaltenhauser S, Weber C, Lin H, Mozayan A, Malhotra A, Constable R, Acosta J, Falcone G, Taylor S, Ment L, Sheth K, Payabvash S. Association of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018. JAMA Network Open 2023, 6: e2314193. PMID: 37200030, PMCID: PMC10196880, DOI: 10.1001/jamanetworkopen.2023.14193.
- Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 functionJami S, Deuis J, Klasfauseweh T, Cheng X, Kurdyukov S, Chung F, Okorokov A, Li S, Zhang J, Cristofori-Armstrong B, Israel M, Ju R, Robinson S, Zhao P, Ragnarsson L, Andersson Å, Tran P, Schendel V, McMahon K, Tran H, Chin Y, Zhu Y, Liu J, Crawford T, Purushothamvasan S, Habib A, Andersson D, Rash L, Wood J, Zhao J, Stehbens S, Mobli M, Leffler A, Jiang D, Cox J, Waxman S, Dib-Hajj S, Neely G, Durek T, Vetter I. Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications 2023, 14: 2442. PMID: 37117223, PMCID: PMC10147923, DOI: 10.1038/s41467-023-37963-2.
- Lecanemab in Early Alzheimer's Disease. Reply.van Dyck C, Sabbagh M, Cohen S. Lecanemab in Early Alzheimer's Disease. Reply. New England Journal Of Medicine 2023, 388: 1631-1632. PMID: 37099355, DOI: 10.1056/nejmc2301380.
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- Demystifying Clinical Appropriateness in Virtual Care and What Is Ahead for Pay Parity: Proceedings of the 3rd Annual Mass General Brigham Virtual Care SymposiumSchwamm L. Demystifying Clinical Appropriateness in Virtual Care and What Is Ahead for Pay Parity: Proceedings of the 3rd Annual Mass General Brigham Virtual Care Symposium. Telemedicine Reports 2023, 4: 53-54. PMID: 37139356, PMCID: PMC10150708, DOI: 10.1089/tmr.2023.0015.
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- Overproduction of Pro-inflammatory Cytokines in New-Onset Refractory Status Epilepticus (NORSE) (S35.002)Hanin A, Cespedes J, Dorgham K, Gopaul M, Hafler D, Navarro V, Gaspard N, Hirsch L. Overproduction of Pro-inflammatory Cytokines in New-Onset Refractory Status Epilepticus (NORSE) (S35.002). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203729.
- Investigating Autoantibody Profiles in Seronegative Myasthenia Gravis (P1-5.005)Masi G, Pham M, Dai Y, Li Y, Karatz T, Oxendine S, Juel V, Ring A, Nowak R, Guptill J, O’Connor K. Investigating Autoantibody Profiles in Seronegative Myasthenia Gravis (P1-5.005). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202639.
- Investigating synaptic changes in Essential Tremor with PET Imaging (P7-11.005)Yang Y, Naganawa M, Hernadenz N, Nguyen N, Nabulsi N, Huang Y, Carson R, Matuskey D, Louis E. Investigating synaptic changes in Essential Tremor with PET Imaging (P7-11.005). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202645.
- Vascular Age and Cognitive Outcomes in an Acute HIV Cohort After Six Years of ART (P13-10.001)Holroyd K, Sacdalan C, Pinyakorn S, Unsombut V, Sriplienchan S, Paul R, Panauphak N, Hsu D, Vasan S, Spudich S, Chan P. Vascular Age and Cognitive Outcomes in an Acute HIV Cohort After Six Years of ART (P13-10.001). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000201802.
- Clinical Implications of Specific Autoantibodies in Chronic Inflammatory Neuropathies (P11-8.013)Bushlyar V, Zubair A, Castillo Y, O’Connor K, DiCapua D, Desai K, Nowak R, Tseng B, Roy B. Clinical Implications of Specific Autoantibodies in Chronic Inflammatory Neuropathies (P11-8.013). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203328.
- A Cross-Sectional Study of Home Blood Pressure Monitoring after Stroke (P11-5.015)Mariscal M, Forman R, Viscoli C, Meuer K, Sheth K, Sansing L, de Havenon A, Sharma R, Kernan W. A Cross-Sectional Study of Home Blood Pressure Monitoring after Stroke (P11-5.015). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203874.
- Neighborhood Deprivation and Race Synergistically Contribute to Undiagnosed Hypertension Leading to Acute Ischemic Stroke: Results from the All of Us Research Program (P6-9.001)Torres-Lopez V, Renedo D, Acosta J, Gill T, Sheth K, Falcone G, Rivier C. Neighborhood Deprivation and Race Synergistically Contribute to Undiagnosed Hypertension Leading to Acute Ischemic Stroke: Results from the All of Us Research Program (P6-9.001). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202154.
- Genetically-Determined LDL Negatively Impacts Clinical Evolution of Ischemic Stroke Survivors (S3.003)Wu K, Rivier C, Demarais Z, Conlon C, Renedo D, Torres-Lopez V, Sharma R, De Havenon A, Sheth K, Falcone G. Genetically-Determined LDL Negatively Impacts Clinical Evolution of Ischemic Stroke Survivors (S3.003). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202173.
- Genetic Analyses of Oral Health and Neuroimaging Markers of Brain Health in Persons without Stroke (S49.001)Rivier C, Renedo D, De Havenon A, Payabvash S, Torres-Lopez V, Gill T, Sheth K, Falcone G. Genetic Analyses of Oral Health and Neuroimaging Markers of Brain Health in Persons without Stroke (S49.001). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202220.
- Sleep Duration is Associated with Clinically Silent Brain Injury in Middle-Aged Persons without Stroke (P1-13.004)Clocchiatti-Tuozzo S, Rivier C, Renedo D, Torres-Lopez V, Payabvash S, Sheth K, Gill T, Falcone G. Sleep Duration is Associated with Clinically Silent Brain Injury in Middle-Aged Persons without Stroke (P1-13.004). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202523.
- Diabetes-Related Polygenic Risk Is Associated with Poor Glycemic Control and Higher Risk of Acute Cardiovascular Events in Stroke Survivors (P3-5.015)Demarais Z, Conlon C, Huo S, Rivier C, Renedo D, Sheth K, Falcone G. Diabetes-Related Polygenic Risk Is Associated with Poor Glycemic Control and Higher Risk of Acute Cardiovascular Events in Stroke Survivors (P3-5.015). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202585.
- Neighborhood Deprivation and Polygenic Contribution to Acute Ischemic Stroke: Results from the All of Us Research Program (S49.007)Rivier C, Acosta J, Renedo D, Gill T, Sheth K, Falcone G. Neighborhood Deprivation and Polygenic Contribution to Acute Ischemic Stroke: Results from the All of Us Research Program (S49.007). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202793.
- Neighborhood Disadvantage and Outcomes Following Intracerebral Hemorrhage (S29.002)Kim J, Kitlen E, Torres-Lopez V, Rivier C, Renedo D, Schlechter M, Kleinberg L, Pish M, Kampp M, Jasak S, Sansing L, Sheth K, Falcone G. Neighborhood Disadvantage and Outcomes Following Intracerebral Hemorrhage (S29.002). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203392.
- Aldosterone Level Predicts Hypertension After ICH in the REDUCE Trial (P3-5.013)Zabinska J, Peng T, Forman R, Schwartz A, Leasure A, Schlechter M, Falcone G, De Havenon A, Sansing L, Lalwani D, Parasuram N, Yadlapalli V, Bushnell C, Mullen M, Cohen J, Cohen D, Messe S, Sheth K. Aldosterone Level Predicts Hypertension After ICH in the REDUCE Trial (P3-5.013). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203612.
- Association Between Hemodynamics After Endovascular Thrombectomy and Cerebral Edema Development (S4.008)Begunova Y, Bartolome D, Olexa M, Kumar A, Chen Y, Peng T, Gutierrez S, Sheth K, Dhar R, Petersen N. Association Between Hemodynamics After Endovascular Thrombectomy and Cerebral Edema Development (S4.008). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202983.
- Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006)Olexa M, Begunova Y, Bartolome D, Peng T, Matouk C, Sheth K, Petersen N. Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202997.
- Increasing Efficiency in Addressing Patient Portal Messaging Demands on Healthcare Systems (P6-7.006)Gordon-Kundu B, Khokhar B. Increasing Efficiency in Addressing Patient Portal Messaging Demands on Healthcare Systems (P6-7.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202747.
- Assessment of Electronic Medical Record Efficiency in Neurologists (P7-7.004)Khokhar B, Brown T, Votto P, Pashankar D. Assessment of Electronic Medical Record Efficiency in Neurologists (P7-7.004). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203223.
- Hypoperfusion intensity ratio is correlated to infarct growth rate parameters when modelled as a logistic growth function (P6-5.022)Galecio-Castillo M, Malaga M, Orozco D, Vivanco-Suarez J, Rodriguez-Calienes A, Zevallos C, Kobsa J, Prasad A, Farooqui M, Petersen N, Ortega-Gutierrez S. Hypoperfusion intensity ratio is correlated to infarct growth rate parameters when modelled as a logistic growth function (P6-5.022). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000204323.
- Imaging biomarkers in the idiopathic inflammatory myopathiesZubair A, Salam S, Dimachkie M, Machado P, Roy B. Imaging biomarkers in the idiopathic inflammatory myopathies. Frontiers In Neurology 2023, 14: 1146015. PMID: 37181575, PMCID: PMC10166883, DOI: 10.3389/fneur.2023.1146015.
- Influence of Cortical Superficial Siderosis in Patients with Mixed Location Cerebral Microbleeds and Intracerebral Hemorrhage (S36.006)Das A, Gokcal E, Biffi A, Regenhardt R, Fouks A, Viswanathan A, Kimberly W, Goldstein J, Schwamm L, Rosand J, Greenberg S, Gurol E. Influence of Cortical Superficial Siderosis in Patients with Mixed Location Cerebral Microbleeds and Intracerebral Hemorrhage (S36.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000204075.
- Acute and Subacute Neurovascular Impact of Cryptogenic Air Emboli (P12-5.020)Gummerson C, Parasram M, Peng T, Picard J, Kahn P, Angelus E, Bhatt S, De Havenon A, Jasne A, Magid-Bernstein J. Acute and Subacute Neurovascular Impact of Cryptogenic Air Emboli (P12-5.020). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000204097.
- Identifying optimal cut points of National Institutes of Health Stroke Scale to Predict Mortality: A Population-based Assessment (P11-5.016)Stanton R, Robinson D, Reeves M, Ding L, Khoury J, Haverbusch M, Alwell K, Adeoye O, Coleman E, De Los Rios La Rosa F, Demel S, Ferioli S, Flaherty M, Jasne A, Khatri P, Mackey J, Martini S, Mistry E, Slavin S, Star M, Woo D, Walsh K, Kissela B, Kleindorfer D. Identifying optimal cut points of National Institutes of Health Stroke Scale to Predict Mortality: A Population-based Assessment (P11-5.016). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203611.
- Imaging biomarkers of cerebral edema automatically extracted from routine CT scans of large vessel occlusion strokesDhar R, Kumar A, Chen Y, Begunova Y, Olexa M, Prasad A, Carey G, Gonzalez I, Bhatia K, Hamed M, Heitsch L, Mainali S, Petersen N, Lee J. Imaging biomarkers of cerebral edema automatically extracted from routine CT scans of large vessel occlusion strokes. Journal Of Neuroimaging 2023, 33: 606-616. PMID: 37095592, PMCID: PMC10524672, DOI: 10.1111/jon.13109.
- Hemorrhagic Conversion of Acute Ischemic StrokeZubair A, Sheth K. Hemorrhagic Conversion of Acute Ischemic Stroke. Neurotherapeutics 2023, 20: 705-711. PMID: 37085684, PMCID: PMC10275827, DOI: 10.1007/s13311-023-01377-1.
- TRPA1 rare variants in chronic neuropathic and nociplastic pain patientsMarchi M, Salvi E, Andelic M, Mehmeti E, D'Amato I, Cazzato D, Chiappori F, Lombardi R, Cartelli D, Devigili G, Bella E, Gerrits M, Almomani R, Malik R, Ślęczkowska M, Mazzeo A, Gentile L, Dib-Hajj S, Waxman S, Faber C, Vecchio E, de Tommaso M, Lauria G. TRPA1 rare variants in chronic neuropathic and nociplastic pain patients. Pain 2023, 164: 2048-2059. PMID: 37079850, PMCID: PMC10443199, DOI: 10.1097/j.pain.0000000000002905.
- Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).Lanctôt K, Chen C, Mah E, Kiss A, Li A, Shade D, Scherer R, Vieira D, Coulibaly H, Rosenberg P, Lerner A, Padala P, Brawman-Mintzer O, van Dyck C, Porsteinsson A, Craft S, Levey A, Burke W, Mintzer J, Herrmann N. Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2). International Psychogeriatrics 2023, 35: 664-672. PMID: 37066690, PMCID: PMC10579450, DOI: 10.1017/s1041610223000327.
- Abstract CT062: GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastomaMellinghoff I, Alexander B, Berry D, Blondin N, Buxton M, Cavenee W, Colman H, de Groot J, de la Fuente M, Ellingson B, Gordon G, Hyddmark E, Khasraw M, Lassman A, Lee E, Li W, Lim M, Mikkelsen T, Nelli A, Perry J, Sulman E, Tanner K, Weller M, Wen P, Cloughesy T. Abstract CT062: GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma. Cancer Research 2023, 83: ct062-ct062. DOI: 10.1158/1538-7445.am2023-ct062.
- Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogensBee G, Lokken-Toyli K, Yeung S, Rodriguez L, Zangari T, Anderson E, Ghosh S, Rothlin C, Brodin P, Khanna K, Weiser J. Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens. Immunity 2023, 56: 1255-1268.e5. PMID: 37059107, PMCID: PMC10330046, DOI: 10.1016/j.immuni.2023.03.018.
- Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zoneGenet N, Genet G, Chavkin N, Paila U, Fang J, Vasavada H, Goldberg J, Acharya B, Bhatt N, Baker K, McDonnell S, Huba M, Sankaranarayanan D, Ma G, Eichmann A, Thomas J, Ffrench-Constant C, Hirschi K. Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. Cell Reports 2023, 42: 112371. PMID: 37043357, PMCID: PMC10564973, DOI: 10.1016/j.celrep.2023.112371.
- Efficient reconstruction of cell lineage trees for cell ancestry and cancerJang Y, Fasching L, Bae T, Tomasini L, Schreiner J, Szekely A, Fernandez T, Leckman J, Vaccarino F, Abyzov A. Efficient reconstruction of cell lineage trees for cell ancestry and cancer. Nucleic Acids Research 2023, 51: e57-e57. PMID: 37026484, PMCID: PMC10250207, DOI: 10.1093/nar/gkad254.
- Provisional practice recommendation for the management of myopathy in VCP‐associated multisystem proteinopathyRoy B, Peck A, Evangelista T, Pfeffer G, Wang L, Diaz‐Manera J, Korb M, Wicklund M, Milone M, Freimer M, Kushlaf H, Villar‐Quiles R, Stojkovic T, Needham M, Palmio J, Lloyd T, Keung B, Mozaffar T, Weihl C, Kimonis V. Provisional practice recommendation for the management of myopathy in VCP‐associated multisystem proteinopathy. Annals Of Clinical And Translational Neurology 2023, 10: 686-695. PMID: 37026610, PMCID: PMC10187720, DOI: 10.1002/acn3.51760.
- Effect of COVID-19 on Acute Ischemic Stroke Severity and Mortality in 2020: Results From the 2020 National Inpatient Samplede Havenon A, Zhou L, Yaghi S, Frontera J, Sheth K. Effect of COVID-19 on Acute Ischemic Stroke Severity and Mortality in 2020: Results From the 2020 National Inpatient Sample. Stroke 2023, 54: e194-e198. PMID: 37021563, PMCID: PMC10121243, DOI: 10.1161/strokeaha.122.041929.
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- Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s diseaseChen C, McCullough A, Gordon B, Joseph-Mathurin N, Flores S, McKay N, Hobbs D, Hornbeck R, Fagan A, Cruchaga C, Goate A, Perrin R, Wang G, Li Y, Shi X, Xiong C, Pontecorvo M, Klein G, Su Y, Klunk W, Jack C, Koeppe R, Snider B, Berman S, Roberson E, Brosch J, Surti G, Jiménez-Velázquez I, Galasko D, Honig L, Brooks W, Clarnette R, Wallon D, Dubois B, Pariente J, Pasquier F, Sanchez-Valle R, Shcherbinin S, Higgins I, Tunali I, Masters C, van Dyck C, Masellis M, Hsiung R, Gauthier S, Salloway S, Clifford D, Mills S, Supnet-Bell C, McDade E, Bateman R, Benzinger T. Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease. European Journal Of Nuclear Medicine And Molecular Imaging 2023, 50: 2669-2682. PMID: 37017737, PMCID: PMC10330155, DOI: 10.1007/s00259-023-06209-0.
- Abstract 1189: MERTK is a target in the microenviroenment of osteolytic bone metastasisEngelmann J, Zarrer J, Riecken K, Waizenegger J, Vargas-Delgado M, Meier L, Bokemeyer C, Pantel K, Alberto E, Ghosh S, Rothlin C, Hesse E, Taipaleenmäki H, Ben-Batalla I, Loges S. Abstract 1189: MERTK is a target in the microenviroenment of osteolytic bone metastasis. Cancer Research 2023, 83: 1189-1189. DOI: 10.1158/1538-7445.am2023-1189.