Macular Degeneration

Brian Hafler’s lab studies cellular mechanisms underlying human retinal diseases. These include age-related macular degeneration (AMD), glaucoma, and stem cell regeneration using machine learning methods such as single-cell transcriptomics, spatial transcriptomics, and single-cell epigenomics. The goal of the research is to identify cellular mechanisms underlying human macular degeneration and glaucoma that can be applied to novel therapies with a focus on neuroinflammation to prevent neuronal death and help preserve vision.