Renee Maria Saliby

2025

• Tumor-Intrinsic and Microenvironmental Determinants of Impaired Antitumor Immunity in Chromophobe Renal Cell Carcinoma

  Labaki C, Saad E, Madsen K, Hobeika C, Bi K, Alchoueiry M, Camp S, Hou Y, Bakouny Z, Matar S, Ahmar N, Nyman J, Zhang L, Priolo C, Rout R, Daou M, Khabibullin D, Salem S, Schindler N, Saliby R, Meli K, Wells J, Pimenta E, Takemura K, Park J, Eid M, Semaan K, Fu J, Denize T, Chehade R, Machaalani M, Nawfal R, Khatoun W, Saleh M, Masri J, Haddad N, Xu W, McGregor B, Hirsch M, Xie W, Heng D, McDermott D, Signoretti S, Van Allen E, Shukla S, Choueiri T, Henske E, Braun D. Tumor-Intrinsic and Microenvironmental Determinants of Impaired Antitumor Immunity in Chromophobe Renal Cell Carcinoma. Journal Of Clinical Oncology 2025, 43: 2639-2654. PMID: 40601888, DOI: 10.1200/jco-25-00234.

  Peer-Reviewed Original Research

  This study investigates the tumor-intrinsic and microenvironmental factors affecting antitumor immunity in chromophobe renal cell carcinoma, showing that immune-cold environments hinder immunotherapy efficacy, emphasizing the need for tailored treatments.

  Full Summary