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INFORMATION FOR

Michael H Nathanson, MD, PhD

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Gladys Phillips Crofoot Professor of Medicine (Digestive Diseases) and Professor of Cell Biology

Titles

Director, Yale Liver Center; Director, Center for Cell and Molecular Imaging

About

Titles

Gladys Phillips Crofoot Professor of Medicine (Digestive Diseases) and Professor of Cell Biology

Director, Yale Liver Center; Director, Center for Cell and Molecular Imaging

Appointments

Other Departments & Organizations

Education & Training

Postdoctoral Fellow
Yale University (1990)
Resident
Columbia-Presbyterian Medical Center (1988)
MD
Case Western Reserve Univ (1985)
PhD
Case Western Reserve Univ (1983)
MS
Massachusetts Institute of Technology (1977)
BS
University of California, Berkeley (1976)

Research

Overview

  • NIH P01 DK57751 (PI: M.H. Nathanson) 04/01/01-04/30/21 Title: Regulation of liver by nuclear calcium signaling Goals: The major goals of this project are to determine the mechanisms by which calcium is regulated in the nucleus of hepatocytes, and to determine the functional effects of nuclear calcium signals in liver. Dr. Nathanson directs Project 1 and the Administrative and Cell Imaging cores of this PPG.
  • NIH P30 DK34989 (PI: M.H. Nathanson) 09/01/84-08/31/20 (NCE pending) Title: Digestive Diseases Research Core Center (Yale Liver Center) Goals: Dr. Nathanson is Director of the Liver Center as well as of the Morphology and Administrative Core components of the Center. The major goals of the Morphology Core are to provide a multidisciplinary center where the research focus is liver structure, function and disease.
  • NIH R01 DK114041 (PI: M.H. Nathanson) 02/01/18-03/31/23 Title: Ca2+ waves in hepatocytes: Mechanisms and effects Goals: The major goals of this project are to determine the mechanisms by which the type 2 InsP3 receptor regulates calcium-mediated bile secretion by hepatocytes, and to determine the role that loss or mis-localization of this receptor plays in the pathogenesis of cholestatic liver disease.
  • NIH R01 DK112797 (PI: M.H. Nathanson) 09/01/17-08/31/22 Title: Molecular regulation of cholestasis in cholangiocytes. Goals: Major goals are to understand the role of type 3 inositol trisphosphate receptor function in cholestatic liver disease
  • NIH T32 DK007356 (PI: M.H. Nathanson) 7/1/84-6/30/24 Title: Investigative Training in Hepatology. Goals: This training grant provides 1) laboratory research training for physicians who have completed clinical training in Gastroenterology and are in preparation for careers as independent investigators in academic Hepatology and research training for recent Ph.D. graduates to prepare them for careers as independent investigators in basic liver-related research.

Medical Subject Headings (MeSH)

Calcium Signaling; Cell Biology; Cell Nucleus; Digestive System Diseases; Hepatocytes; Liver

Research at a Glance

Yale Co-Authors

Frequent collaborators of Michael H Nathanson's published research.

Publications

2024

2023

2020

2015

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Clinical Trials

Current Trials

Academic Achievements and Community Involvement

  • activity

    Member

    CommitteesVA
  • activity

    Member

    Peer Review Groups and Grant Study SectionsNIH
  • activity

    Member

    Peer Review Groups and Grant Study SectionsNIH
  • activity

    Member

    CommitteesAASLD
  • honor

    Assoc of American Physicians (AAP)

    National Award
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Clinical Care

Overview

Michael H. Nathanson, MD, PhD, specializes in treating patients with liver disease.

He is a professor of medicine (digestive diseases) and of cell biology at Yale School of Medicine. In addition to his clinical work, he serves as section chief of digestive diseases; director of both the Yale Liver Center and the Center for Cell and Molecular Imaging; and an active researcher.

Clinical Specialties

Internal Medicine; Hepatology

Fact Sheets

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Board Certifications

  • Internal Medicine

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1988

Yale Medicine News

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Get In Touch

Contacts

Email
Academic Office Number
Appointment Number
Office Fax Number
Clinic Fax Number
Mailing Address

Yale School of Medicine

Department of Medicine (Digestive Diseases), PO Box 208019

New Haven, CT 06520-8019

United States

Locations

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