Discoveries & Impact

More than 70,000 Medicare beneficiaries receive care in long-term acute care hospitals for prolonged medical illnesses such as dependence on the ventilator after pneumonia. Very little has been known about their long-term functional and cognitive outcomes after hospitalization.

A team at Yale, led by Martin Schwartz, PhD, Robert W. Berliner Professor of Medicine (cardiology), has identified a protein that helps your body sense and respond to changes in this shear stress.

Older adults often take multiple medications, some of which may interact with each other to cause adverse effects. Physicians address this problem through “deprescribing,” which involves systematic discontinuation of medications where the risks outweigh the benefits.

Individuals in nursing homes with severe dementia are experiencing an increasing trend toward receiving high-intensity medical treatments despite the limited potential benefits and distress they cause. Yale investigators sought to understand the factors influencing this increasing trend.

Sudden cardiac arrests represent a significant cause of disease in young people, with athletes being at higher risk. For athletes who have previously had cardiac arrest, an implantable cardiac defibrillator (ICD) is the primary avenue to prevent a subsequent cardiac event.

Faculty from the Yale Department of Internal Medicine’s Section of Infectious Diseases have recently contributed a clinical case to JAMA’s Clinical Challenge series. The case involved a patient with poorly controlled type 1 diabetes, who presented to the emergency room with a one-week history of weakness.

New research from a group of Yale physicians sheds light on the clinical reasoning strategies used by expert clinicians in handling complex medical cases.

A recent study conducted by Yale researchers focused on the intersection of unhealthy alcohol use and adherence to pre-exposure prophylaxis (PrEP) among gay, bisexual, and other men who have sex with men. The research, undertaken between February 2019 and July 2020, involved semi-structured interviews with 15 men who have sex with men in Providence, Rhode Island and New Haven, Connecticut, who were prescribed PrEP and had screened positive for unhealthy alcohol use.

Tick-borne diseases, primarily transmitted by Ixodes scapularis (black-legged or deer tick), are increasingly prevalent in the United States, surpassing diseases spread by mosquitoes. With over 490,000 annual cases, these diseases, including Lyme disease, babesiosis, anaplasmosis, and Powassan virus, present significant public health challenges.