2024
Hypoperfusion Intensity Ratio as an Indirect Imaging Surrogate in Patients With Anterior Circulation Large‐Vessel Occlusion and Association of Baseline Characteristics With Poor Collateral Status
Hamam O, Gudenkauf J, Moustafa R, Cho A, Montes D, Sharara M, Moustafa A, Radmard M, Nabi M, Chen K, Sepehri S, Shin C, Mazumdar I, Kim M, Mohseni A, Malhotra A, Romero J, Yedavalli V. Hypoperfusion Intensity Ratio as an Indirect Imaging Surrogate in Patients With Anterior Circulation Large‐Vessel Occlusion and Association of Baseline Characteristics With Poor Collateral Status. Journal Of The American Heart Association 2024, 13: e030897. PMID: 39158547, PMCID: PMC11963918, DOI: 10.1161/jaha.123.030897.Peer-Reviewed Original ResearchConceptsAnterior circulation large-vessel occlusionHypoperfusion intensity ratioLarge-vessel occlusionAcute ischemic strokeAdmission laboratory findingsCollateral statusAIS-LVOAdmission National InstitutesBaseline characteristicsLaboratory findingsConsecutive patientsPoor CSCryptogenic causeComputed tomography perfusion dataPretreatment computed tomography perfusionAssociation of baseline characteristicsPoor collateral statusPatient baseline characteristicsComputed tomography perfusionMultivariate logistic regressionInfarct growth rateMale patientsRetrospective studyClinical outcomesLogistic regression modelsPuzzling undetectable haptoglobin in a transfused pregnant patient
Chaves Rivera M, Choucair I, Vera M, El-Khoury J, Figueroa Villalba C. Puzzling undetectable haptoglobin in a transfused pregnant patient. Clinica Chimica Acta 2024, 561: 119829. PMID: 38917868, DOI: 10.1016/j.cca.2024.119829.Peer-Reviewed Original ResearchAcute hemolytic transfusion reactionUndetectable haptoglobin levelUndetectable haptoglobinPregnant patientsHaptoglobin levelsB-cell acute lymphocytic leukemiaPregnancy-related physiological changesTrimester-specific reference intervalsReference intervalsCenters for Disease Control (CDC) criteriaDiagnosis of hemolysisNon-pregnant counterpartsTrimester of pregnancyAcute lymphocytic leukemiaHemolytic transfusion reactionsMultidisciplinary approach to patient careFollow-up visitRed cell unitsLactate dehydrogenasePhysiological changesRBC transfusionThird trimesterLymphocytic leukemiaLaboratory findingsImmunological markersComparative Study of the Efficacy and Side Effects of Brand-Name and Generic Clozapine for Long-Term Maintenance Treatment Among Korean Patients With Schizophrenia: A Retrospective Naturalistic Mirror-Image Study
Kang N, Yoon H, Kim H, Jeong J, Kim M, Kwon J. Comparative Study of the Efficacy and Side Effects of Brand-Name and Generic Clozapine for Long-Term Maintenance Treatment Among Korean Patients With Schizophrenia: A Retrospective Naturalistic Mirror-Image Study. Psychiatry Investigation 2024, 21: 311-320. PMID: 38569589, PMCID: PMC10990625, DOI: 10.30773/pi.2023.0413.Peer-Reviewed Original ResearchMirror-image studyMaintenance treatmentTreatment-resistant schizophreniaFormulation of clozapineLong-term maintenance treatmentConcentration-to-dose ratioClozapine useGeneric clozapineClozapineClozarilPsychiatric hospitalNo significant differenceSchizophreniaKorean patientsMedical records of patientsClinical insightsBlood test findingsElectronic medical records of patientsSignificant differenceRecords of patientsBrand-name formulationConcomitant medicationsCo-MedicationHospitalization durationLaboratory findingsRing Chromosome 19
Wen J, Chong M. Ring Chromosome 19. 2024, 271-278. DOI: 10.1007/978-3-031-47530-6_23.Peer-Reviewed Original ResearchPercentage of mosaicismRare chromosomal aberrationGenotype-phenotype correlationSeverity of clinical featuresGenomic investigationsChromosome 19Genetic imbalanceVariable clinical manifestationsRare genetic abnormalitySurvive into adulthoodCarrier parentsSevere phenotypeClinical featuresLaboratory findingsInherited casesClinical manifestationsGenetic abnormalitiesChromosomal aberrationsClinical implicationsMosaicismFamilial transmissionPhenotypeComprehensive understandingIntellectual disabilityPatientsClinical characteristics and influencing factors of severe fever with thrombocytopenia syndrome complicated by viral myocarditis: a retrospective study
Du Q, Yu J, Chen Q, Chen X, Jiang Q, Deng L, Li A, Xiong Y. Clinical characteristics and influencing factors of severe fever with thrombocytopenia syndrome complicated by viral myocarditis: a retrospective study. BMC Infectious Diseases 2024, 24: 240. PMID: 38389047, PMCID: PMC10885462, DOI: 10.1186/s12879-024-09096-4.Peer-Reviewed Original ResearchConceptsNT-proBNPConsciousness disorderClinical characteristicsViral myocarditisMultivariate analysisThrombocytopenia syndromeElevated platelet countElevated NT-proBNPIndependent risk factorRate of hypotensionSevere feverValues of LDHElevated LDHAbdominal painCardiac ultrasonographyMethodsRetrospective analysisPlatelet countD-dimerRetrospective studyLaboratory findingsClinical manifestationsAtrial fibrillationAbnormal electrocardiogramClinical dataRisk factors
2023
Clinical Course and Mutational Analysis of Patients with Cystine Stone: A Single-Center Experience
Jeong J, Oh K, Sohn J, Jun D, Shin J, Lee K, Lee J. Clinical Course and Mutational Analysis of Patients with Cystine Stone: A Single-Center Experience. Biomedicines 2023, 11: 2747. PMID: 37893120, PMCID: PMC10604214, DOI: 10.3390/biomedicines11102747.Peer-Reviewed Original ResearchClinical courseCystine stonesMutation analysis of patientsSingle-center experienceAnalysis of patientsTertiary medical centerClinical presentationRecurrent stonesSingle-centerLaboratory findingsKorean patientsPatient phenotypesPatientsGenetic disordersKorean cohortCystinuriaMedical CenterGenetic analysisMutation analysisSurgeryB mutationsType A.Type B mutationsPhenotypeGenotypesThe emergence of influenza B as a major respiratory pathogen in the absence of COVID-19 during the 2021–2022 flu season in China
Chang D, Lin M, Song N, Zhu Z, Gao J, Li S, Liu H, Liu D, Zhang Y, Sun W, Zhou X, Yang B, Li Y, Wang L, Xiao Z, Li K, Xing L, Xie L, Sharma L. The emergence of influenza B as a major respiratory pathogen in the absence of COVID-19 during the 2021–2022 flu season in China. Virology Journal 2023, 20: 189. PMID: 37620959, PMCID: PMC10463403, DOI: 10.1186/s12985-023-02115-x.Peer-Reviewed Original ResearchConceptsInfluenza BAverage ageCOVID-19Influenza-like illnessNumber of patientsMajor respiratory pathogenCOVID-19 testCOVID-19-related restrictionsCell death markersClinical characteristicsFever clinicYounger patientsAppropriate vaccinationPatient characteristicsSubstantial morbidityRespiratory virusesSeasonal virusesLaboratory findingsPositivity rateInfluenza ARespiratory pathogensPreventive strategiesSecondary infectionSevere casesFlu seasonFirst case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient
Fuller R, Cederroth T, Patel G, Reidy J, Patiño L, Ramírez J, Bassily-Marcus A, Paniz-Mondolfi A. First case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient. American Journal Of Transplantation 2023, 23: 1995-1999. PMID: 37516244, DOI: 10.1016/j.ajt.2023.07.017.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsOrgan transplant recipientsKidney transplant recipientsTransplant recipientsMale kidney transplant recipientsCases of mpoxGenomic analysisLaboratory findingsFatal courseProphylaxis effortsPublic health authoritiesPatient populationHousehold contactsRisk factorsAutopsy findingsHealth authoritiesRecipientsPatientsMPOXDiseaseMenGenomeSecondary transmissionCerebral venous thrombosis after ChAdOx1 nCoV-19 vaccination: a systematic review.
Song T, Shin J, Yon D, Lee S, Hwang S, Hwang J, Park S, Lee S, Lee M, Kim M, Koyanagi A, Tizaoui K, Kim J, Smith L. Cerebral venous thrombosis after ChAdOx1 nCoV-19 vaccination: a systematic review. European Review For Medical And Pharmacological Sciences 2023, 27: 404-410. PMID: 36647889, DOI: 10.26355/eurrev_202301_30894.Peer-Reviewed Original ResearchConceptsCerebral venous thrombosisChAdOx1 nCoV-19 vaccineIntracerebral hemorrhageThrombocytopenia syndromeCase seriesVenous thrombosisCase reportPresence of cerebral venous thrombosisSystematic review of case reportsDose of ChAdOx1 nCoV-19 vaccineHistory of intracerebral hemorrhageReview of case reportsSystematic reviewHigher mortality rateYounger age groupsClinical featuresLaboratory findingsTreatment modalitiesFrequent historyMultivariate analysisWeb of Science databasesThrombosisPatientsMortality rateAge groups
2022
Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review
Tan J, Shukla A, Hu J, Majumdar S. Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review. Case Reports In Endocrinology 2022, 2022: 6538800. PMID: 36504598, PMCID: PMC9729038, DOI: 10.1155/2022/6538800.Peer-Reviewed Case Reports and Technical NotesDirect oral anticoagulantsAdrenal hemorrhageAntiphospholipid syndromeSafety of DOACsBilateral adrenal hemorrhageDeep venous thrombosesPrimary adrenal insufficiencySpontaneous adrenal hemorrhageCases of patientsPubMed/MEDLINEWarrants further studyAldosterone physiologyAPLS patientsAdrenal involvementEndocrine complicationsOral anticoagulantsVenous thrombosesAdrenal insufficiencyCortisol deficiencyAdrenal functionCortisol replacementAdrenal glandCase reportLaboratory findingsZona reticularisAssociation between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry
Collins W, Chang A, Weng Y, Dahlen A, O'Brien C, Hom J, Ahuja N, Rodriguez F, Rohatgi N. Association between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry. Journal Of Obesity & Metabolic Syndrome 2022, 31: 277-281. PMID: 36058896, PMCID: PMC9579478, DOI: 10.7570/jomes22042.Peer-Reviewed Original ResearchBody mass indexLength of stayClass II obese patientsPatients admitted to intensive careBMI subjectsNational COVID-19 registryBody mass index categoriesII obese patientsPoor clinical outcomesAdult COVID-19 patientsHalf-day reductionCritically ill patientsFunction of body mass indexCOVID-19 registryCalculated length of stayCOVID-19 patientsObese patientsLaboratory findingsClinical outcomesRespiratory statusMass indexDose-dependentlyMedical historyIll patientsIntensive carePredominance of Severe Plasma Leakage in Pediatric Patients With Severe Dengue in Puerto Rico
Paz-Bailey G, Sánchez-González L, Torres-Velasquez B, Jones E, Perez-Padilla J, Sharp T, Lorenzi O, Delorey M, Munoz-Jordan J, Tomashek K, Waterman S, Alvarado L, Rivera-Amill V. Predominance of Severe Plasma Leakage in Pediatric Patients With Severe Dengue in Puerto Rico. The Journal Of Infectious Diseases 2022, 226: 1949-1958. PMID: 35510941, PMCID: PMC10015274, DOI: 10.1093/infdis/jiac165.Peer-Reviewed Original ResearchConceptsSevere plasma leakageSevere dengueReverse transcriptase-polymerase chain reactionPlasma leakageSevere bleedingDengue virusHistory of feverDays of presentationTranscriptase-polymerase chain reactionYear oldsNonsevere dengueOrgan involvementCommon presentationPediatric patientsClinical manifestationsDengue patientsEmergency departmentLaboratory findingsIgM enzymePatientsSerum samplesImmunosorbent assayDengueChain reactionBleeding
2021
Concomitant factor VIII inhibitor and lupus anticoagulant in an asymptomatic patient
Jacobs JW, Gisriel SD, Iyer K, Rinder HM. Concomitant factor VIII inhibitor and lupus anticoagulant in an asymptomatic patient. Journal Of Thrombosis And Thrombolysis 2021, 53: 945-949. PMID: 34697688, PMCID: PMC8544916, DOI: 10.1007/s11239-021-02591-4.Peer-Reviewed Original ResearchConceptsPartial thromboplastin timeLupus anticoagulantFVIII inhibitorsAsymptomatic patientsFactor VIIIComprehensive hematologic evaluationLife-threatening hemorrhageTypical laboratory findingsDistinctive clinical presentationFactor VIII inhibitorsRisk of thrombosisSigns of hemorrhageSevere bleeding diathesisCoagulation factor VIIIImmunosuppressive therapyClinical presentationClinical symptomsPathologic antibodiesVIII inhibitorsLaboratory findingsHematologic evaluationUnique presentationBleeding diathesisThromboplastin timeAutoantibodiesCOVID-19 vaccines: Keeping pace with SARS-CoV-2 variants
Cevik M, Grubaugh ND, Iwasaki A, Openshaw P. COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants. Cell 2021, 184: 5077-5081. PMID: 34534444, PMCID: PMC8445744, DOI: 10.1016/j.cell.2021.09.010.Peer-Reviewed Original ResearchHypocomplementemia (C3) as an independent predictor for children with acute post-streptococcal glomerulonephritis: a long-term observation.
Han K, Lee K, Park S, Yu R, Kim S, Lee I, Han S, Kim H, Kronbichler A, Li H, Koyanagi A, Jacob L, Shin J, Kim J, Smith L. Hypocomplementemia (C3) as an independent predictor for children with acute post-streptococcal glomerulonephritis: a long-term observation. European Review For Medical And Pharmacological Sciences 2021, 25: 5674-5683. PMID: 34604959, DOI: 10.26355/eurrev_202109_26786.Peer-Reviewed Original ResearchConceptsAcute post-streptococcal glomerulonephritisPost-streptococcal glomerulonephritisGroup IIClinical manifestationsC3 levelsGroup INephritic symptomsRisk of complicationsChest X-rayDevelopment of edemaLevels of BUNPulmonary edemaClinical characteristicsGeneralized edemaLaboratory findingsEdemaOliguriaMedical recordsGroup I.Disease severityKorean childrenGlomerulonephritisPatientsSeveritySouth Korean children24-Hydroxylase Deficiency Due to CYP24A1 Sequence Variants: Comparison With Other Vitamin D−mediated Hypercalcemia Disorders
Azer S, Vaughan L, Tebben P, Sas D. 24-Hydroxylase Deficiency Due to CYP24A1 Sequence Variants: Comparison With Other Vitamin D−mediated Hypercalcemia Disorders. Journal Of The Endocrine Society 2021, 5: bvab119. PMID: 34337279, PMCID: PMC8317629, DOI: 10.1210/jendso/bvab119.Peer-Reviewed Original ResearchPositive family historyUrinary calcium:creatinine ratioFamily historyCalcium:creatinine ratioLumbar spine Z-scoreClinical characteristics of patientsRetrospectively reviewed laboratoryIdentified 9 patientsSpine Z-scoreVitamin D toxicityFisher's exact testCharacteristics of patientsLoss-of-function variantsWilcoxon rank sum testRank sum testSerum calciumClinical characteristicsLaboratory findingsCreatinine ratioInactive metabolitesExact testMayo ClinicSymptom onsetGene variantsPatientsThe Research-Practice Psychotherapy Wars: The Case of Group Psychotherapy in the Treatment of PTSD
Greene L. The Research-Practice Psychotherapy Wars: The Case of Group Psychotherapy in the Treatment of PTSD. International Journal Of Group Psychotherapy 2021, 71: 393-423. PMID: 38449227, DOI: 10.1080/00207284.2021.1890088.Peer-Reviewed Original ResearchPosttraumatic stress disorderRandomized control trialTreatment of PTSDClinical practice guidelinesGroup psychotherapyLaboratory findingsPractice guidelinesControl trialClinical practiceExperienced cliniciansStress disorderOutcomes researchCliniciansConsiderable pushbackDissemination effortsResearch prioritiesPsychotherapyPrimary strategyFindingsOutcome focusTrialsRecurrent Hematochezia in a Returning Traveler
Gleeson SE, Zhang X, Azar MM. Recurrent Hematochezia in a Returning Traveler. JAMA 2021, 325: 1558-1559. PMID: 33666646, DOI: 10.1001/jama.2021.0368.Peer-Reviewed Original ResearchRelation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients With Coronavirus Disease 2019 (from the Yale COVID-19 Cardiovascular Registry)
Pareek M, Singh A, Vadlamani L, Eder M, Pacor J, Park J, Ghazizadeh Z, Heard A, Cruz-Solbes AS, Nikooie R, Gier C, Ahmed ZV, Freeman JV, Meadows J, Smolderen KGE, Lampert R, Velazquez EJ, Ahmad T, Desai NR. Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients With Coronavirus Disease 2019 (from the Yale COVID-19 Cardiovascular Registry). The American Journal Of Cardiology 2021, 146: 99-106. PMID: 33539857, PMCID: PMC7849530, DOI: 10.1016/j.amjcard.2021.01.029.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsCoronavirus disease 2019Risk factorsHigher troponin TCardiovascular diseaseCardiovascular eventsHospitalized patientsLaboratory findingsMental statusDisease 2019Multivariable binary logistic regression analysisTroponin TMajor adverse cardiovascular eventsPre-existing cardiovascular diseaseHigher C-reactive proteinCOVID-19 positive patientsPredictors of MACEPrevious ventricular arrhythmiaUse of P2YAdverse cardiovascular eventsProspective cohort studyTertiary care centerC-reactive proteinBinary logistic regression analysisPoor prognostic markerChest CT abnormalities in COVID-19: a systematic review
Ghayda R, Lee K, Kim J, Lee S, Hong S, Kim K, Kim K, Seok J, Kim H, Seo J, Lee S, Koyanagi A, Jacob L, Smith L, Li H, Kronbichler A, Shin J. Chest CT abnormalities in COVID-19: a systematic review. International Journal Of Medical Sciences 2021, 18: 3395-3402. PMID: 34522166, PMCID: PMC8436104, DOI: 10.7150/ijms.50568.Peer-Reviewed Original ResearchConceptsChest CT findingsGround-glass opacitiesCT findingsComputed tomographyCT findings of COVID-19Chest CT abnormalitiesWhite blood cell countCharacteristics of chest CTFindings of COVID-19Case series studyComprehensive diagnostic approachBlood cell countSystematic reviewCOVID-19 patientsBilateral lungsChest CTReviewed reference listsAir bronchogramCT abnormalitiesRadiological characteristicsLaboratory findingsVascular enlargementCase reportClinical severityDiabetes mellitus
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