2021
Concomitant factor VIII inhibitor and lupus anticoagulant in an asymptomatic patient
Jacobs JW, Gisriel SD, Iyer K, Rinder HM. Concomitant factor VIII inhibitor and lupus anticoagulant in an asymptomatic patient. Journal Of Thrombosis And Thrombolysis 2021, 53: 945-949. PMID: 34697688, PMCID: PMC8544916, DOI: 10.1007/s11239-021-02591-4.Peer-Reviewed Original ResearchConceptsPartial thromboplastin timeLupus anticoagulantFVIII inhibitorsAsymptomatic patientsFactor VIIIComprehensive hematologic evaluationLife-threatening hemorrhageTypical laboratory findingsDistinctive clinical presentationFactor VIII inhibitorsRisk of thrombosisSigns of hemorrhageSevere bleeding diathesisCoagulation factor VIIIImmunosuppressive therapyClinical presentationClinical symptomsPathologic antibodiesVIII inhibitorsLaboratory findingsHematologic evaluationUnique presentationBleeding diathesisThromboplastin timeAutoantibodies
2000
Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A
Powell J, Bush M, Harrison J, Abildgaard C, Vosburgh E, Thompson A, Hurst D. Safety and efficacy of solvent/detergent‐treated antihaemophilic factor with an added 80 °C terminal dry heat treatment in patients with haemophilia A. Haemophilia 2000, 6: 140-149. PMID: 10792471, DOI: 10.1046/j.1365-2516.2000.00407.x.Peer-Reviewed Original ResearchConceptsHeat-treated preparationsPlasma-derived factor VIII concentrateCrossover pharmacokinetic studyFactor VIII inhibitorsHome treatment programHemophilia A patientsTerminal dry heat treatmentFactor VIII concentrateViral inactivation processesSolvent/detergent treatmentA patientsFactor VIII preparationsClinical parametersVIII inhibitorsHaemophilia treatmentPatientsHemophilia AVIII concentrateTreatment programRare reportsAntihaemophilic factorPharmacokinetic studyDevelopment of inhibitorsTreatmentNon-enveloped viruses
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply