2025
Influence of resilience and social support on the association between food insecurity and depressive symptoms during pregnancy: A moderated mediation model
Carandang R, Lewis J, Masters C, Ickovics J, Cunningham S. Influence of resilience and social support on the association between food insecurity and depressive symptoms during pregnancy: A moderated mediation model. Journal Of Affective Disorders 2025, 383: 435-442. PMID: 40334869, DOI: 10.1016/j.jad.2025.05.020.Peer-Reviewed Original ResearchConceptsSocial supportDepressive symptomsFood insecurityAssociation of food insecurityInfluence of food insecurityAdverse effects of food insecurityEffects of food insecurityGroup prenatal carePregnant individualsChronic food insecurityInfluence of resilienceMediation modelPrenatal careTrimester of pregnancyRisk factorsIndirect associationsModerated Mediation ModelAssociationInsecurityPregnancySymptomsSupportChronically foodCareIndividualsHypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study
Alshikho M, Haghighi N, Ravi R, Solomon V, Rangel E, Pyne J, Bista K, Chang J, Lippert R, Cotton‐Samuel D, Cedano S, De La Cruz Vasquez N, Haro C, Chiu J, Chen Y, Reddy U, McNeil B, Pemberton V, Yee L, Parrish T, Brickman A, Miller E, Investigators F. Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study. Pregnancy 2025, 1 DOI: 10.1002/pmf2.70020.Peer-Reviewed Original ResearchHistory of HDPCerebral blood flowRegional cerebral blood flowWhite matter hyperintensityBrain MRIGray matter volumeHypertensive disordersRisk of cognitive declineAssociation of HDPSmall-for-gestational age infantsCognitive declineFractional anisotropyPilot studyHypertensive disorders of pregnancyRegional gray matter volumeWhite matter hyperintensity volumeMicrovascular brain injuryAssociated with long-term impairmentDisorders of pregnancyDementia riskMulticenter prospective cohortTrimester of pregnancyHigh-resolution brain MRIHealth StudyIndex deliveryHaptoglobin in pregnancy: Trimester-specific reference intervals
Rivera M, Choucair I, Vera M, Lee E, El-Khoury J, Villalba C. Haptoglobin in pregnancy: Trimester-specific reference intervals. American Journal Of Clinical Pathology 2025, aqaf012. PMID: 40037777, DOI: 10.1093/ajcp/aqaf012.Peer-Reviewed Original ResearchThird trimesterFirst-trimesterHaptoglobin valuesTrimester-specific reference intervalsReference intervalsRemnant serum samplesTrimester of pregnancyMann-Whitney testPregnancy patientsNonpregnant populationNonpregnant counterpartsImmunological markersIntravascular hemolysisTrimesterDecreased haptoglobinPregnancyPregnant individualsMann-WhitneyRoche Cobas 8000Nonparametric reference intervalsSerum samplesCobas 8000Quality improvement projectHemolysisPhysiological changes
2024
Cerebellar Purkinje Cell Activity Regulates White Matter Response and Locomotor Function after Neonatal Hypoxia
Kundu S, Ghaemmaghami J, Sanidas G, Wolff N, Vij A, Byrd C, Simonti G, Triantafyllou M, Jablonska B, Dean T, Koutroulis I, Gallo V, Kratimenos P. Cerebellar Purkinje Cell Activity Regulates White Matter Response and Locomotor Function after Neonatal Hypoxia. Journal Of Neuroscience 2024, 45: e0899242024. PMID: 39472064, PMCID: PMC11694407, DOI: 10.1523/jneurosci.0899-24.2024.Peer-Reviewed Original ResearchWhite matter injuryNeonatal hypoxiaLocomotor deficitsPurkinje cellsWM injuryOligodendrocyte maturationCerebellar Purkinje cell activityNeuronal activitySurvivors of prematurityPC activityWhite matterTrimester of pregnancyCerebellar Purkinje cellsPurkinje cell activityRestoring neuronal activityLocomotor dysfunctionMultielectrode array recordingsHx miceOligodendrocyte precursor cellsPreterm neonatesPotential therapeutic interventionsNeonatal injuryGABAergic interneuronsCerebellar WMEffect of HXMaternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach
Euclydes V, Braga C, Gouveia G, Martinez R, Camilo C, Simões S, Martins-Jr D, Fracolli L, Argeu A, Ferraro A, Matijasevich A, Fatori D, Miguel E, Polanczyk G, Brentani H. Maternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach. Brain Behavior & Immunity - Health 2024, 40: 100832. PMID: 39193418, PMCID: PMC11347843, DOI: 10.1016/j.bbih.2024.100832.Peer-Reviewed Original ResearchMaternal immune responseTrimester of pregnancyImmune responseNeurodevelopmental outcomesImmunological markersImmunological biomarkersMaternal childhood traumaNeurodevelopmental trajectoriesMother's immune responseEarly stages of pregnancyWeeks of pregnancyMaternal psychosocial stressStages of pregnancyStages of gestationRandomized clinical trialsAnti-inflammatory stateMaternal stress experienceNeurodevelopmental scoresImmune system responseInflammatory biomarkersClinical trialsPregnancyPsychosocial stress conditionBlood samplesLinear mixed-effects modelsPuzzling undetectable haptoglobin in a transfused pregnant patient
Chaves Rivera M, Choucair I, Vera M, El-Khoury J, Figueroa Villalba C. Puzzling undetectable haptoglobin in a transfused pregnant patient. Clinica Chimica Acta 2024, 561: 119829. PMID: 38917868, DOI: 10.1016/j.cca.2024.119829.Peer-Reviewed Original ResearchAcute hemolytic transfusion reactionUndetectable haptoglobin levelUndetectable haptoglobinPregnant patientsHaptoglobin levelsB-cell acute lymphocytic leukemiaPregnancy-related physiological changesTrimester-specific reference intervalsReference intervalsCenters for Disease Control (CDC) criteriaDiagnosis of hemolysisNon-pregnant counterpartsTrimester of pregnancyAcute lymphocytic leukemiaHemolytic transfusion reactionsMultidisciplinary approach to patient careFollow-up visitRed cell unitsLactate dehydrogenasePhysiological changesRBC transfusionThird trimesterLymphocytic leukemiaLaboratory findingsImmunological markersA multisite study to develop and validate first trimester, circulating microparticle biomarkers for tiered risk stratification of spontaneous preterm birth in nulliparas
Rosenblatt K, Zhang Z, Doss R, Gurnani P, Grobman W, Silver R, Parry S, Reddy U, Cao S, Haas D. A multisite study to develop and validate first trimester, circulating microparticle biomarkers for tiered risk stratification of spontaneous preterm birth in nulliparas. American Journal Of Obstetrics And Gynecology 2024, 232: 319.e1-319.e21. PMID: 38789072, PMCID: PMC11584339, DOI: 10.1016/j.ajog.2024.05.032.Peer-Reviewed Original ResearchIn vitro diagnostic multivariate index assaySpontaneous preterm birthGestational agePreterm birthLow riskModerate riskPrediction of spontaneous preterm birthHR groupRisk ratioHigh riskMonitoring Mothers-to-BeNulliparous Pregnancy Outcomes StudyTrimester of pregnancyMultivariate index assayPregnancy Outcomes StudyNested case-control designStatistically significant differencePregnant patientsWeeks gestationMass spectrometry assayCase-control designRisk stratificationStratify riskMothers-to-beStratification toolReview of Genetic and Artificial Intelligence approaches to improving Gestational Diabetes Mellitus Screening and Diagnosis in sub-Saharan Africa
Gadhia V, Loyal J. Review of Genetic and Artificial Intelligence approaches to improving Gestational Diabetes Mellitus Screening and Diagnosis in sub-Saharan Africa. The Yale Journal Of Biology And Medicine 2024, 97: 67-72. PMID: 38559462, PMCID: PMC10964814, DOI: 10.59249/zbsc2656.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitus screeningGestational diabetes mellitusSub-Saharan AfricaSingle nucleotide polymorphismsBarriers to successful integrationImplementation of AISub-Saharan African womenSub-SaharanPredictor of gestational diabetes mellitusRisk of gestational diabetes mellitusAssociated with gestational diabetes mellitusDiabetes mellitus screeningEarly identificationBlack South African cohortTrimester of pregnancySouth African cohortSub-Saharan African populationsHealthcare systemImprove screeningResource settingsSub-Saharan African regionField of healthcareGenetic variantsGoogle ScholarAfrican cohortDiscrimination and perinatal depressive symptoms: The protective role of social support and resilience
Masters C, Lewis J, Hagaman A, Thomas J, Carandang R, Ickovics J, Cunningham S. Discrimination and perinatal depressive symptoms: The protective role of social support and resilience. Journal Of Affective Disorders 2024, 354: 656-661. PMID: 38484882, DOI: 10.1016/j.jad.2024.03.039.Peer-Reviewed Original ResearchPerinatal depressive symptomsGroup prenatal careAdverse effects of discriminationSocial supportDepressive symptomsPrenatal careEffects of discriminationPregnant peopleAssociated with less depressive symptomsAssociated with depressive symptomsEffect of social supportModerating effect of social supportHigh social supportLess depressive symptomsPerinatal depressionSocial determinantsMonths postpartumLinear regression modelsSelf-report measuresPostpartum periodTrimester of pregnancyPostpartumPsychological factorsRegression modelsCare
2022
Licit and illicit drug use across trimesters in pregnant women endorsing past-year substance use: Results from National Survey on Drug Use and Health (2009–2019)
Peltier MR, Roberts W, Verplaetse TL, Burke C, Zakiniaeiz Y, Moore K, McKee SA. Licit and illicit drug use across trimesters in pregnant women endorsing past-year substance use: Results from National Survey on Drug Use and Health (2009–2019). Archives Of Women's Mental Health 2022, 25: 819-827. PMID: 35737132, PMCID: PMC9359119, DOI: 10.1007/s00737-022-01244-6.Peer-Reviewed Original ResearchConceptsPast-month substance useFirst trimesterPast-year substance usePregnant womenIllicit substance useDrug useSubstance useThird trimesterCross-sectional population-based dataSignificant public health concernTrimester of pregnancyPrescription pain medicationPopulation-based dataPerinatal substance useIllicit drug useMethodsThe present studyPublic health concernMinority of womenNational surveyLicit substance usePain medicationSimilar low ratesSecond trimesterLate trimesterLicit substancesMaternal blood metal concentrations are associated with matrix metalloproteinases (MMPs) among pregnant women in Puerto Rico
Kim C, Cathey A, Watkins D, Mukherjee B, Rosario-Pabón Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Maternal blood metal concentrations are associated with matrix metalloproteinases (MMPs) among pregnant women in Puerto Rico. Environmental Research 2022, 209: 112874. PMID: 35123972, PMCID: PMC10443181, DOI: 10.1016/j.envres.2022.112874.Peer-Reviewed Original ResearchConceptsBlood metal concentrationsAdverse birth outcomesMetal concentrationsAssociated with matrix metalloproteinasesMatrix metalloproteinasesBirth outcomesFetal sexHealthy pregnancyLinear mixed effects modelsUterine remodelingPregnant womenFemale fetusesExposure to heavy metalsHeavy metal exposureCustomized Luminex assayFetal sex effectLevels of inflammatory cytokinesTrimester of pregnancyBlood metal levelsMetal levelsHeavy metalsMetal exposureMeasured blood concentrationsLuminex assayMale fetuses
2020
Electrocardiographic QT Intervals in Infants Exposed to Hydroxychloroquine Throughout Gestation
Friedman DM, Kim M, Costedoat-Chalumeau N, Clancy R, Copel J, Phoon CK, Cuneo B, Cohen R, Masson M, Wainwright BJ, Zahr N, Saxena A, Izmirly P, Buyon JP. Electrocardiographic QT Intervals in Infants Exposed to Hydroxychloroquine Throughout Gestation. Circulation Arrhythmia And Electrophysiology 2020, 13: e008686. PMID: 32907357, PMCID: PMC7668319, DOI: 10.1161/circep.120.008686.Peer-Reviewed Original ResearchMeSH KeywordsAntiviral AgentsCardiotoxicityDrug Administration ScheduleDrug MonitoringElectrocardiographyFemaleFetal BloodFetal HeartGestational AgeHeart BlockHeart RateHumansHydroxychloroquineInfantInfant, NewbornMalePredictive Value of TestsPregnancyRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsBlood levelsSSA/Ro antibodiesHistorical healthy controlsHydroxychloroquine blood levelsCord blood levelsCongenital heart blockSystemic lupus erythematosusTrimester of pregnancyEfficacy of hydroxychloroquineCoronavirus disease-19Electrocardiographic QT intervalCOVID-19 studiesPostnatal ECGRo antibodiesIndividual pregnanciesLupus erythematosusQTc prolongationAntiviral therapyHeart blockClinical efficacyRheumatic conditionsDrug exposureMaternal useCord bloodDisease-19Economic Status, Nutrition and Pregnancy Cost; A Vicious Cycle in Pregnancy
Gunarathne S, Wickramasinghe N, Agampodi T, Prasanna R, Agampodi S. Economic Status, Nutrition and Pregnancy Cost; A Vicious Cycle in Pregnancy. Current Developments In Nutrition 2020, 4: nzaa054_068. PMCID: PMC7257277, DOI: 10.1093/cdn/nzaa054_068.Peer-Reviewed Original ResearchPregnant womenNormal mothersPregnancy costsConsecutive pregnant womenTrimester of pregnancyPublic health clinicsLarge cohort studyPublic health problemVicious cycleUnderweight mothersCohort studyUnderweight groupMean agePregnant mothersMaternal nutritionHealth clinicsAnthropometric measurementsHealth problemsNutritional statusEconomic statusPregnancyHousehold incomeWomenMothersSignificant differences
2009
Biliary Disease in Pregnancy With an Emphasis on the Role of ERCP
Al-Hashem H, Muralidharan V, Cohen H, Jamidar PA. Biliary Disease in Pregnancy With an Emphasis on the Role of ERCP. Journal Of Clinical Gastroenterology 2009, 43: 58-62. PMID: 19020461, DOI: 10.1097/mcg.0b013e31818acf80.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyCommon bile duct stonesBile duct stonesDuct stonesRole of ERCPTherapeutic endoscopic retrograde cholangiopancreatographyPremature delivery rateTrimester of pregnancyExcellent diagnostic modalityIncidence of gallstonesSpontaneous abortion rateStandard of careMagnetic resonance imagingBenefits of interventionsAbdominal ultrasonographyEndoscopic sphincterotomyNormal cholangiogramPregnant patientsSelect patientsSymptomatic patientsBiliary diseaseRetrograde cholangiopancreatographySecond trimesterSurgical interventionEndoscopic ultrasonography
2000
Infant Birth Weight Among Women With or at High Risk for HIV Infection: The Impact of Clinical, Behavioral, Psychosocial, and Demographic Factors
Ickovics J, Ethier K, Koenig L, Wilson T, Walter E, Fernandez M. Infant Birth Weight Among Women With or at High Risk for HIV Infection: The Impact of Clinical, Behavioral, Psychosocial, and Demographic Factors. Health Psychology 2000, 19: 515-523. PMID: 11129354, DOI: 10.1037/0278-6133.19.6.515.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesConnecticutFemaleFollow-Up StudiesHealth BehaviorHIV SeropositivityHumansInfant, Low Birth WeightInfant, NewbornMultivariate AnalysisNew YorkNorth CarolinaOdds RatioPregnancyPregnancy Complications, InfectiousPrenatal CareRiskRisk-TakingSocial SupportSocioeconomic FactorsStress, PsychologicalConceptsLow birth weightBirth weightPregnant womenHigh riskHIV-negative pregnant womenHIV-seropositive pregnant womenInfant birth weightHIV risk factorsHIV specialty clinicsMedical chart reviewTrimester of pregnancyAdverse birth outcomesBirth outcome dataImpact of ClinicalLogistic regression analysisImpact of HIVChart reviewHIV infectionHIV-positiveBirth outcomesGestational ageHIV transmissionPrenatal clinicsWeeks postpartumRisk factors
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