2024
Nerve growth factor gene polymorphisms may be associated with heroin dependence in women but do not mediate specific personality traits
Kuo S, Lin C, Tsou C, Yeh Y, Yang B, Chen C, Huang C, Huang S. Nerve growth factor gene polymorphisms may be associated with heroin dependence in women but do not mediate specific personality traits. European Archives Of Psychiatry And Clinical Neuroscience 2024, 275: 487-498. PMID: 39311999, PMCID: PMC11976897, DOI: 10.1007/s00406-024-01906-9.Peer-Reviewed Original ResearchTridimensional Personality QuestionnairePersonality traitsHeroin dependenceHarm avoidanceBarratt Impulsiveness Scale version 11Tridimensional Personality Questionnaire scoresTrait of impulsivityAssociated with heroin dependenceChinese versionBIS-11Reward processingPersonality QuestionnaireAssociated with traitsFemale HD patientsNeurotrophic factors nerve growth factorFemale subgroupPotential confounding effectsHD patientsGenetic contributionPersonsTraitsCo-occurrenceGene polymorphismsVersion 11Confounding effects
2023
An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder
Worden B, Tolin D, Stevens M. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal Of Affective Disorders 2023, 345: 410-418. PMID: 38706461, PMCID: PMC11068362, DOI: 10.1016/j.jad.2023.10.148.Peer-Reviewed Original ResearchCognitive behavioral therapyBrain activityEffective cognitive behavioral therapyCognitive-behavioral group therapyTreatment attendanceBrain dysfunctionFunctional magnetic resonanceDiscarding taskExecutive functioningAbnormal brain activityNeural predictorsHomework completionGroup therapyTreatment engagementHD patientsTreatment complianceHD treatmentPremotor areasActivity abnormalitiesPatient's abilityBrain regionsTherapeutic benefitTreatment retentionRegion activityPrior researchChanges in Neural Activity Following a Randomized Trial of Cognitive Behavioral Therapy for Hoarding Disorder
Tolin D, Levy H, Hallion L, Wootton B, Jaccard J, Diefenbach G, Stevens M. Changes in Neural Activity Following a Randomized Trial of Cognitive Behavioral Therapy for Hoarding Disorder. Journal Of Consulting And Clinical Psychology 2023, 91: 242-250. PMID: 36877480, PMCID: PMC10175200, DOI: 10.1037/ccp0000804.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMedial intraparietal areaDorsal anterior cingulate cortexIntraparietal areaHD patientsRostral cingulateDorsolateral prefrontalBehavioral therapyVentral insular cortexDACC activationAnterior intraparietal areaNeural activityGroup cognitive behavioral therapyAnterior cingulate cortexRight dorsolateral prefrontalFunctional magnetic resonance imagingMagnetic resonance imagingCaudal cingulateClinical trialsInsular cortexRight amygdalaTherapeutic benefitSymptom reductionCingulate cortexResonance imagingPrevalence of Latent Tuberculosis Infection among Patients Undergoing Regular Hemodialysis in Disenfranchised Communities: A Multicenter Study during COVID-19 Pandemic
Ismail M, Zarriaa N, Osman M, Helfawi S, Kabbara N, Chatah A, Kamaleddine A, Alameddine R, Dabboussi F, Hamze M. Prevalence of Latent Tuberculosis Infection among Patients Undergoing Regular Hemodialysis in Disenfranchised Communities: A Multicenter Study during COVID-19 Pandemic. Medicina 2023, 59: 654. PMID: 37109612, PMCID: PMC10142838, DOI: 10.3390/medicina59040654.Peer-Reviewed Original ResearchConceptsLatent tuberculosis infectionMultivariable logistic regression analysisHD patientsLogistic regression analysisTuberculosis infectionDialysis unitsMulticenter cross-sectional studyQFT-Plus resultsActive tuberculosis diseaseQuantiFERON-TB GoldHospital dialysis unitRisk of mortalityTB control measuresCross-sectional studyRegression analysisCOVID-19 pandemicLow socioeconomic statusLTBI statusQFT-PlusRegular HDRegular hemodialysisElderly patientsLTBI prevalenceHemodialysis patientsPatient transmission
2022
Bioaccumulation of Blood Long-Chain Fatty Acids during Hemodialysis
Liu T, Dogan I, Rothe M, Reichardt J, Knauf F, Gollasch M, Luft F, Gollasch B. Bioaccumulation of Blood Long-Chain Fatty Acids during Hemodialysis. Metabolites 2022, 12: 269. PMID: 35323712, PMCID: PMC8949028, DOI: 10.3390/metabo12030269.Peer-Reviewed Original ResearchChronic kidney diseaseRed blood cellsLong-chain fatty acidsHD treatmentUpper limbEnd-stage renal disease patientsPeripheral tissue perfusionSingle HD treatmentRenal disease patientsFatty acid statusVenous blood samplesFatty acidsCardiovascular eventsESRD patientsHD patientsKidney diseaseDisease patientsVenous bloodHemodialysis treatmentAcid statusUremia altersBlood samplesTissue perfusionLCFA levelsFatty acids n
2020
Implantation of the clinical‐grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid‐lesioned rodent model of Huntington's disease
Yoon Y, Kim HS, Jeon I, Noh J, Park HJ, Lee S, Park I, Stevanato L, Hicks C, Corteling R, Barker RA, Sinden JD, Song J. Implantation of the clinical‐grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid‐lesioned rodent model of Huntington's disease. Stem Cells 2020, 38: 936-947. PMID: 32374064, PMCID: PMC7496241, DOI: 10.1002/stem.3191.Peer-Reviewed Original ResearchConceptsMedium spiny neuronsNeural stem cell lineHuntington's diseaseQuinolinic acid (QA) lesion rat modelChronic ischemic stroke patientsStriatal medium spiny neuronsCell linesImmortalized neural stem cell linesIschemic stroke patientsDisease-modifying therapiesSignals of efficacyGlial scar formationHost brain tissueHuman neural stem cell lineSignificant behavioral improvementAutosomal dominant neurodegenerative diseaseCTX0E03 cellsEndogenous neurogenesisBDNF expressionGABAergic neuronsHD patientsStroke patientsFluoro-GoldRetrograde labelSpiny neurons
2019
Survival after major lower extremity amputation in patients with end-stage renal disease
Arhuidese I, Nejim B, Aji E, Canner J, Malas M. Survival after major lower extremity amputation in patients with end-stage renal disease. Journal Of Vascular Surgery 2019, 70: 1291-1298. PMID: 31543169, DOI: 10.1016/j.jvs.2018.12.055.Peer-Reviewed Original ResearchConceptsKnee amputeesKnee amputationBurden of peripheral artery diseaseLower extremity amputationEstimates of life expectancyEnd-stage renal diseaseRisk-adjusted mortalityAmputation levelExtremity amputationRace-specific differencesRT recipientsHealthcare providersPeripheral arterial diseaseHD patientsLong-term mortalityUnited States Renal Data SystemMedian survivalBKAKneeHispanicsLife expectancyRenal transplantationMLEAAmputationCardiovascular disease
2018
Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants
Arhuidese I, Nejim B, Locham S, Malas M. Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants. Journal Of Vascular Surgery 2018, 69: 850-856. PMID: 30583904, DOI: 10.1016/j.jvs.2018.05.252.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsInfrainguinal bypass surgeryRenal transplantationRT patientsPatient survivalOutcome of infrainguinal bypass surgeryHD patientsBenefits of renal transplantationLimb salvageEnd-stage renal diseaseCox regression analysisLong-term outcomesEvaluate 30-dayRisk-adjusted analysisPopulation-based cohortCritical limb ischemiaU.S. Renal Data SystemRetrospective reviewBypass surgeryKaplan-MeierSurgery outcomesPatient-level riskRenal diseaseHemodialysis patientsLimb ischemiaPatients
2017
Racial disparities after infrainguinal bypass surgery in hemodialysis patients
Arhuidese I, Wang S, Locham S, Faateh M, Nejim B, Malas M. Racial disparities after infrainguinal bypass surgery in hemodialysis patients. Journal Of Vascular Surgery 2017, 66: 1163-1174. PMID: 28647200, DOI: 10.1016/j.jvs.2017.04.044.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBlack or African AmericanBlood Vessel Prosthesis ImplantationChi-Square DistributionDatabases, FactualFemaleHealthcare DisparitiesHispanic or LatinoHumansKaplan-Meier EstimateKidney DiseasesLimb SalvageLogistic ModelsMaleMedicareMiddle AgedMultivariate AnalysisOdds RatioPeripheral Arterial DiseasePostoperative ComplicationsProcess Assessment, Health CarePropensity ScoreProportional Hazards ModelsRenal DialysisRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyWhite PeopleConceptsInfrainguinal bypass surgeryGraft failureHD patientsPeripheral arterial diseaseLimb salvageBypass surgeryEvaluate long-term graft patencyArtery diseaseWhite patientsGraft patencyBlack patientsSurgical treatment of peripheral arterial diseaseLong-term graft failurePrimary assisted patencyAcute graft failureCox regression analysisLong-term mortalityLong-term graft patencyAll-Cause MortalityLimb lossTreatment of peripheral arterial diseasePopliteal-tibial bypassAssisted patencyPrimary patencySecondary patency
2016
Different diuretic dose and response in acute decompensated heart failure: Clinical characteristics and prognostic significance
Palazzuoli A, Testani JM, Ruocco G, Pellegrini M, Ronco C, Nuti R. Different diuretic dose and response in acute decompensated heart failure: Clinical characteristics and prognostic significance. International Journal Of Cardiology 2016, 224: 213-219. PMID: 27657476, DOI: 10.1016/j.ijcard.2016.09.005.Peer-Reviewed Original ResearchConceptsLower diuretic efficiencyChronic kidney diseaseDiuretic efficiencyAdverse eventsDose administrationAcute decompensated heart failureDecompensated heart failureAdverse event ratesDiuretic doseWRF occurrenceRenal dysfunctionClinical characteristicsRenal functionHeart failureHD patientsMultivariable analysisClinical statusPrognostic significanceAdverse outcomesContinuous administrationKidney diseaseDE patientsLD patientsBest modalityPatientsAbstract 102: Carotid Endarterectomy versus Stenting in Patients on Chronic Hemodialysis
Arhuidese I, Obeid T, Nejim B, Yin K, Wang S, Malas M. Abstract 102: Carotid Endarterectomy versus Stenting in Patients on Chronic Hemodialysis. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.102.Peer-Reviewed Original ResearchLong-term outcomesPropensity Score Matching AnalysisCohort of HD patientsRisk of perioperative strokeScore matching analysisCarotid endarterectomyPerioperative strokeHD patientsCompare long-term outcomesMean follow-upMultivariate Cox regressionMatching AnalysisStroke-free survivalPredictors of perioperative strokeCarotid artery stenosisPerioperative stroke rateFree survivalStroke free survivalChronic hemodialysisSymptomatic statusCarotid revascularizationFollow-upCox regressionArtery stenosisMedicare database
2015
Detecting mutant huntingtin protein in HD patients
Brennand K. Detecting mutant huntingtin protein in HD patients. Science Translational Medicine 2015, 7 DOI: 10.1126/scitranslmed.aac8559.Commentaries, Editorials and LettersTrends in Incident Hemodialysis Access and Mortality
Malas MB, Canner JK, Hicks CW, Arhuidese IJ, Zarkowsky DS, Qazi U, Schneider EB, Black JH, Segev DL, Freischlag JA. Trends in Incident Hemodialysis Access and Mortality. JAMA Surgery 2015, 150: 441-448. PMID: 25738981, DOI: 10.1001/jamasurg.2014.3484.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseHemodialysis cathetersArteriovenous fistulaArteriovenous graftsLower mortalityRenal diseaseVascular accessHD outcomesNational Kidney Foundation Kidney Disease Outcomes Quality InitiativeKidney Foundation Kidney Disease Outcomes Quality InitiativeMultivariable Cox proportional hazards modelsPrior renal replacement therapyUS Renal Data SystemCox proportional hazards modelArteriovenous fistula useIncident HD patientsInitiation of hemodialysisRetrospective cohort studyRenal replacement therapyProportional hazards modelFistula useCohort studySurvival benefitHD patientsPropensity score-matching technique
2013
Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition
Tolin DF, Witt ST, Stevens MC. Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Research 2013, 221: 142-148. PMID: 24389161, PMCID: PMC3946244, DOI: 10.1016/j.pscychresns.2013.11.009.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGo/NoGo taskFunctional magnetic resonance imagingOCD patientsHD patientsResponse inhibitionNoGo taskHealthy controlsGo/NoGo task performanceDistinct neural underpinningsRight orbitofrontal gyrusErrors of commissionNeural underpinningsOrbitofrontal activationTask performanceCorrect rejectsMagnetic resonance imagingHemodynamic activityFrontal hypoactivityNeural activityOrbitofrontal gyrusBehavioral dataHemodynamic responsePatientsPreliminary evidence
2011
IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease
Sadagurski M, Cheng Z, Rozzo A, Palazzolo I, Kelley G, Dong X, Krainc D, White M. IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease. Journal Of Clinical Investigation 2011, 121: 4070-4081. PMID: 21926467, PMCID: PMC3195462, DOI: 10.1172/jci46305.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsBrainDisease Models, AnimalDisease ProgressionFemaleForkhead Box Protein O1Forkhead Transcription FactorsGene ExpressionHumansHuntington DiseaseInsulin Receptor Substrate ProteinsLongevityMaleMiceMice, KnockoutMice, Mutant StrainsMice, TransgenicMitochondriaOxidative StressSignal TransductionConceptsHuntington's diseaseOxidative stressMouse modelProgression of HDMitochondrial dysfunctionMajor risk factorR6/2 mouse modelNeuronal oxidative stressMitochondrial functionHD-like symptomsHD patientsNumber of autophagosomesTranscription factor FOXO1Risk factorsR6/2 miceSlow progressionTherapeutic approachesExpression of IRS2HD progressionLife spanNeurodegenerative diseasesIRS2 levelsProgressionDiseaseMice
2010
Poster 14: Evaluation of Novel Radiotracers Targeting Non-Dopaminergic Striatal Biomarkers in HD: 18F-FPEB and PET Imaging for Metabotropic Glutamate Receptor Type 5 (mGluR5) Expression in Healthy Subjects and Subjects with Huntington Disease (HD)
Russell D, Jennings D, Tamagnan G, Seibyl J, Koren A, Zubal G, Marek K. Poster 14: Evaluation of Novel Radiotracers Targeting Non-Dopaminergic Striatal Biomarkers in HD: 18F-FPEB and PET Imaging for Metabotropic Glutamate Receptor Type 5 (mGluR5) Expression in Healthy Subjects and Subjects with Huntington Disease (HD). Neurotherapeutics 2010, 7: 142. DOI: 10.1016/j.nurt.2009.09.016.Peer-Reviewed Original ResearchHD subjectsHuntington's diseaseMGluR5 expressionTemporal lobeHuman studiesStandardized uptake value ratioPET imagingEnkephalinergic striatal neuronsLimbic cortical areasMean SUV ratioEarly brain changesEarly HD patientsUptake value ratioGray matter areasPromising PET radiotracerCerebellar reference regionSymptomatic HD subjectsNon-human primatesHD patientsNeuron lossStriatal neuronsIntense uptakeHealthy controlsBrain changesAge 44
2006
Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil
Silva L, Silva M, Rodart I, Lopes G, Costa F, Melo M, Gusmão E, Reis M. Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil. Brazilian Journal Of Medical And Biological Research 2006, 39: 595-602. PMID: 16648896, DOI: 10.1590/s0100-879x2006000500005.Peer-Reviewed Original ResearchConceptsHepatitis C virus infectionCandidate blood donorsC virus infectionHD patientsHCV infectionBlood donorsGenotype 1Virus infectionAnti-HCV seroprevalenceAnti-HCV prevalenceHCV genotype distributionAnti-HCV antibodiesHCV genotype 1Chronic liver diseaseTransfusion-transmitted infectionsCross-sectional studyDifferent dialysis centresHCV seroprevalenceChronic hemodialysisHemodialysis populationHCV RNAPositive patientsHemodialysis patientsHCV genotypesLiver disease
2005
Long-term treatment of sleep breathing disorder in a patient with Huntington's disease
Banno K, Hobson DE, Kryger MH. Long-term treatment of sleep breathing disorder in a patient with Huntington's disease. Parkinsonism & Related Disorders 2005, 11: 261-264. PMID: 15878590, DOI: 10.1016/j.parkreldis.2005.01.005.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureSleep breathing disordersApnea-hypopnea indexBreathing disordersHuntington's diseaseRapid eye movement (REM) sleepPositive airway pressureObstructive sleep apneaLong-term treatmentEye movement sleepQuality of lifeAutosomal dominant neurodegenerative disorderAirway pressureHD patientsSleep apneaRespiratory arousalsMovement sleepDominant neurodegenerative disorderDaytime alertnessSleep structureNeurodegenerative disordersDiseaseDisordersApneaPatients
2003
Diagnosing Hirschsprung's disease: Increasing the odds of a positive rectal biopsy result
Lewis NA, Levitt MA, Zallen GS, Zafar MS, Iacono KL, Rossman JE, Caty MG, Glick PL. Diagnosing Hirschsprung's disease: Increasing the odds of a positive rectal biopsy result. Journal Of Pediatric Surgery 2003, 38: 412-416. PMID: 12632358, DOI: 10.1053/jpsu.2003.50070.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetBarium SulfateBiopsyChildChild, PreschoolCohort StudiesConstipationDiagnosis, DifferentialEnemaEnterocolitisFecal ImpactionFemaleHirschsprung DiseaseHumansInfantInfant, NewbornMaleMeconiumPhysical ExaminationRectumRetrospective StudiesUnnecessary ProceduresVomitingConceptsPassage of meconiumHirschsprung's diseaseRectal biopsyAbdominal distensionIdiopathic constipationContrast enemaHD patientsPhysical examinationUnnecessary rectal biopsiesPercent of patientsOnset of symptomsRadiologic evaluationChi2 testingClassic triadRadiographic evaluationBiopsy resultsConcurrent cohortRetrospective analysisPatient historyConstipationPatientsBiopsyVomitingDistensionFirst week
2000
Reproducibility of ambulatory blood pressure monitoring in hemodialysis patients
Peixoto A, Santos S, Mendes R, Crowley S, Maldonado R, Orias M, Mansoor G, White W. Reproducibility of ambulatory blood pressure monitoring in hemodialysis patients. American Journal Of Kidney Diseases 2000, 36: 983-990. PMID: 11054355, DOI: 10.1053/ajkd.2000.19100.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure monitoringInterdialytic ambulatory blood pressure monitoringBlood pressure monitoringPost-HD valuesHD patientsPressure monitoringReproducibility of ABPMDrug regimenHemodialysis patientsHemodialysis practiceHD sessionNocturnal declineInterdialytic periodPatientsBP determinationRegimenPeriodSleepCoefficient of variation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply