2025
Linking attention bias to youth social anxiety and depression: Insights from computational modeling of the affective Posner task
Edgar E, Castagna P, Delpech R, Crowley M. Linking attention bias to youth social anxiety and depression: Insights from computational modeling of the affective Posner task. Journal Of Affective Disorders 2025, 388: 119764. PMID: 40562109, DOI: 10.1016/j.jad.2025.119764.Peer-Reviewed Original ResearchDepressive symptom severityParent-reported social anxietyAttentional biasSocial anxietySymptom severityPubertal statusFunction of pubertal statusThreat-related stimuliDrift diffusion model parametersSymptoms of psychopathologyYouth social anxietyLatent cognitive processesSymptoms of anxietyDrift diffusion parametersHigher pubertal statusPosner taskDepressive symptomatologyPredicting anxietyDepressive symptomsCognitive processesEvidence accumulationDrift rateAnxietyDepressionBehavioral dataThe Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
Chopra S, Cocuzza C, Lawhead C, Ricard J, Labache L, Patrick L, Kumar P, Rubenstein A, Moses J, Chen L, Blankenbaker C, Gillis B, Germine L, Harpaz-Rotem I, Yeo B, Baker J, Holmes A. The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry. Scientific Data 2025, 12: 923. PMID: 40456751, PMCID: PMC12130183, DOI: 10.1038/s41597-025-04895-z.Peer-Reviewed Original ResearchConceptsTask-based functional MRIHigh-resolution anatomical scansBrain-behavior relationshipsHealthy comparison groupFeatures of brain functionFunctional network organizationClinically relevant symptomsPsychiatric illnessFunctional MRINeuroimaging dataResting-stateBrain functionClinical neuroscienceCognitive AssessmentBehavioral dataConnectome ProjectAnatomical scansComparison groupDiagnostic criteriaNetwork organizationRelevant symptomsPsychiatryActivating effectIndividualsTransdiagnostic
2024
Multimodal predictive modeling: Scalable imaging informed approaches to predict future brain health
Ajith M, Spence J, Chapman S, Calhoun V. Multimodal predictive modeling: Scalable imaging informed approaches to predict future brain health. Journal Of Neuroscience Methods 2024, 414: 110322. PMID: 39608579, PMCID: PMC11687617, DOI: 10.1016/j.jneumeth.2024.110322.Peer-Reviewed Original ResearchStatic functional network connectivityHealth constructsNeuroimaging dataBrain healthResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingSupport vector regressionFunctional network connectivityRandom forestCognitive performanceAssessment-onlyRs-fMRINeural patternsBehavioral outcomesBehavioral dataDiverse data sourcesNeural connectionsPsychological stateTraining stageMagnetic resonance imagingLongitudinal changesNetwork connectivityBrainPerformance evaluationVector regressionDigital Dietary Behaviors in Individuals With Depression: Real-World Behavioral Observation
Zhu Y, Zhang R, Yin S, Sun Y, Womer F, Liu R, Zeng S, Zhang X, Wang F. Digital Dietary Behaviors in Individuals With Depression: Real-World Behavioral Observation. JMIR Public Health And Surveillance 2024, 10: e47428. PMID: 38648087, PMCID: PMC11074900, DOI: 10.2196/47428.Peer-Reviewed Original ResearchConceptsModerate-severe depressionDietary behaviorsMultivariate logistic regression analysisDepression severityMild depressionIrregular eating patternsLogistic regression analysisDetect depressionDinner patternEating breakfastMeal patternsEating patternsDaily lunchSelf-reported dataSupport vector machine analysisBehavior monitoringNaturalistic settingsVector machine analysisFood choicesDepressionProfile of changesBehavioral data
2022
Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility
Kafadar E, Fisher VL, Quagan B, Hammer A, Jaeger H, Mourgues C, Thomas R, Chen L, Imtiaz A, Sibarium E, Negreira AM, Sarisik E, Polisetty V, Benrimoh D, Sheldon AD, Lim C, Mathys C, Powers AR. Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility. Biological Psychiatry 2022, 92: 772-780. PMID: 35843743, PMCID: PMC10575690, DOI: 10.1016/j.biopsych.2022.05.007.Peer-Reviewed Original ResearchConceptsCH rateIncoming sensory evidenceSensory evidencePerceptual statesTask performanceComputational psychiatrySubset of participantsPrior expectationsHallucination severityBehavioral dataSymptom severityPast experienceStable measureHallucinationsPsychotic symptomsHallucination frequencyTaskSymptom expressionBayesian modelState markerHallucinatorsNonhallucinatorsOverweightingPerceptionSymptom risk
2019
Strategy-dependent modulation of cortical pain circuits for the attenuation of pain
Schulz E, Stankewitz A, Witkovský V, Winkler A, Tracey I. Strategy-dependent modulation of cortical pain circuits for the attenuation of pain. Cortex 2019, 113: 255-266. PMID: 30711854, DOI: 10.1016/j.cortex.2018.12.014.Peer-Reviewed Original ResearchConceptsCognitive strategiesBrain activityDifferent cognitive strategiesPain attenuationUnderlying neuronal mechanismsPain-related brain activityVariability of performanceNeuroscientific techniquesNeurofeedback techniquesT fMRIPerception of painBehavioral dataBehavioral studiesTrial levelBrain regionsCortical regionsNeuronal mechanismsCortical feedbackInsular cortexDistractionTaskPain perceptionPotential predispositionAttenuation of painPerception
2013
Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition
Tolin DF, Witt ST, Stevens MC. Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Research 2013, 221: 142-148. PMID: 24389161, PMCID: PMC3946244, DOI: 10.1016/j.pscychresns.2013.11.009.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGo/NoGo taskFunctional magnetic resonance imagingOCD patientsHD patientsResponse inhibitionNoGo taskHealthy controlsGo/NoGo task performanceDistinct neural underpinningsRight orbitofrontal gyrusErrors of commissionNeural underpinningsOrbitofrontal activationTask performanceCorrect rejectsMagnetic resonance imagingHemodynamic activityFrontal hypoactivityNeural activityOrbitofrontal gyrusBehavioral dataHemodynamic responsePatientsPreliminary evidenceBehavior outcome after ischemic and hemorrhagic stroke, with similar brain damage, in rats
Mestriner R, Miguel P, Bagatini P, Saur L, Boisserand L, Baptista P, Xavier L, Netto C. Behavior outcome after ischemic and hemorrhagic stroke, with similar brain damage, in rats. Behavioural Brain Research 2013, 244: 82-89. PMID: 23403282, DOI: 10.1016/j.bbr.2013.02.001.Peer-Reviewed Original ResearchConceptsDays post-surgeryBrain damageEndotelin-1Post-surgeryNeurobiological differencesWalking recoveryOpen fieldBehavioral testsBehavioral outcomesSkilled walkingBehavioral dataStroke subtypesRecovery profileStroke heterogeneityHemorrhagic strokeHemorrhaged ratsHemorrhagic eventsSpontaneous recovery profileWistar ratsBrainClinical trialsHemorrhagic subtypesVolume of tissueHemorrhagic insultLesion size
2012
Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model
Murray JD, Anticevic A, Gancsos M, Ichinose M, Corlett PR, Krystal JH, Wang XJ. Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model. Cerebral Cortex 2012, 24: 859-872. PMID: 23203979, PMCID: PMC3948492, DOI: 10.1093/cercor/bhs370.Peer-Reviewed Original ResearchConceptsWorking memoryNeural levelSpatial WM taskWorking Memory ModelSpatial working memoryPersistent activity patternsWM representationsWM taskWM maintenanceBrain mechanismsWM deficitsMicrocircuit dysfunctionPrefrontal cortexCognitive deficitsBehavioral dataMemory modelBehavioral variabilityWM deteriorationCognitive impairmentCortical disinhibitionExcitation-inhibition balanceMain model predictionsDisinhibitionBehavioral deficitsDeficitsThe temporal derivative of expected utility: A neural mechanism for dynamic decision-making
Zhang X, Hirsch J. The temporal derivative of expected utility: A neural mechanism for dynamic decision-making. NeuroImage 2012, 65: 223-230. PMID: 22963852, PMCID: PMC5841235, DOI: 10.1016/j.neuroimage.2012.08.063.Peer-Reviewed Original ResearchConceptsNeural mechanismsBehavioral dataHuman neural correlatesNovel experimental paradigmDistinct neural activitySuperior parietal lobulePosterior cingulate cortexReal-world tasksNeural correlatesFuture rewardsParietal lobuleExperimental paradigmFMRI analysisCingulate cortexNeural activityWorld tasksBrain regionsSupplementary motorCentral gyrusDynamic decision processIndependent manipulationContinuous decisionsDecision processVentral pallidumFMRI
2011
Markers of preparatory attention predict visual short-term memory performance
Murray A, Nobre A, Stokes M. Markers of preparatory attention predict visual short-term memory performance. Neuropsychologia 2011, 49: 1458-1465. PMID: 21335015, PMCID: PMC3318119, DOI: 10.1016/j.neuropsychologia.2011.02.016.Peer-Reviewed Original ResearchConceptsCue-related changesContralateral delay activityPreparatory attentionVisual short-term memoryMemory-based performancePreparatory brain activityEncoded itemsEncoding taskProbe itemERP markersMemory representationsMemory loadMemory recallShort-term memoryAccurate memory recallBrain activityRecall probabilityRecall accuracySpatial attentionAttention positivityPrecision of recallSpatial cuesBehavioral dataEarly attentionDelayed activation
2008
Erratum: Behavioural improvements with thalamic stimulation after severe traumatic brain injury
Schiff N, Giacino J, Kalmar K, Victor J, Baker K, Gerber M, Fritz B, Eisenberg B, Biondi T, O’Connor J, Kobylarz E, Farris S, Machado A, McCagg C, Plum F, Fins J, Rezai A. Erratum: Behavioural improvements with thalamic stimulation after severe traumatic brain injury. Nature 2008, 452: 120-120. DOI: 10.1038/nature06818.Peer-Reviewed Original Research
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