Exposure range matters: considering nonlinear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes
Guo P, Warren J, Deziel N, Liew Z. Exposure range matters: considering nonlinear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes. American Journal Of Epidemiology 2024, 194: 1043-1051. PMID: 39227151, DOI: 10.1093/aje/kwae309.Peer-Reviewed Original ResearchNon-linear associationMeta-analysisHeterogeneity of effect estimatesEffect estimatesPotential non-linear associationsExposure-outcome relationshipsRisk of preterm birthSubgroup meta-analysisBirth outcomesPollution exposureMeta-analytic approachMeta-analysesEffect sizeEnvironmental pollutant exposureResults heterogeneityExposure levelsHealth effectsPreterm birthEvidence-based policymakingPrenatal exposurePotential heterogeneityMean birth weightBirth weightMethodological challengesCut-off choiceAssociations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study
Park S, Siwakoti R, Ferguson K, Cathey A, Hao W, Cantonwine D, Mukherjee B, McElrath T, Meeker J. Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study. Environmental Research 2024, 255: 119205. PMID: 38782334, PMCID: PMC11421857, DOI: 10.1016/j.envres.2024.119205.Peer-Reviewed Original ResearchMaternal thyroid hormonesThyroid hormone concentrationsPolycyclic aromatic hydrocarbon metabolitesThyroid hormonesPolycyclic aromatic hydrocarbonsPregnancy outcomesHormone concentrationsFetal sex-specific effectsPAH exposureBayesian kernel machine regressionPotential non-linear associationsHormone physiologyAromatic hydrocarbonsThyroid hormone physiologyPregnancy physiologyFetal growthFetal sexFetal developmentUrinary PAH metabolitesSerial measurementsPregnancyUrinary polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon exposureStudy visitsThyroid
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