Oriana Ciani, PhD
About
Research
Publications
2024
Design and Features of Pricing and Payment Schemes for Health Technologies: A Scoping Review and a Proposal for a Flexible Need-Driven Classification
Ardito V, Ciani O, Drummond M. Design and Features of Pricing and Payment Schemes for Health Technologies: A Scoping Review and a Proposal for a Flexible Need-Driven Classification. PharmacoEconomics 2024, 1-25. PMID: 39405025, DOI: 10.1007/s40273-024-01435-2.Peer-Reviewed Original ResearchHealth technologiesPreferred Reporting ItemsGroups of keywordsMethodsA Preferred Reporting ItemsScoping reviewDecision makersReporting ItemsIndependent reviewersOutcome componentsSystematic reviewPayment schemeNarrative formatSchemeComprehensive categorizationCollection requirementsProblem of affordabilityHealthClassificationFeatures of pricingOutcomes of Patients With Early and Locally Advanced Lung Cancer: Protocol for the Italian Lung Cancer Observational Study (LUCENT)
Bertolaccini L, Ciani O, Lucchi M, Zaraca F, Bertani A, Crisci R, Spaggiari L, Group L. Outcomes of Patients With Early and Locally Advanced Lung Cancer: Protocol for the Italian Lung Cancer Observational Study (LUCENT). JMIR Research Protocols 2024, 13: e57183. PMID: 39378423, PMCID: PMC11496920, DOI: 10.2196/57183.Peer-Reviewed Original ResearchConceptsLocally advanced lung cancerNon-small cell lung cancerOutcomes of patientsAdvanced lung cancerLung cancerWeb-based registryINTERNATIONAL REGISTERED REPORT IDENTIFIERObservational studySecondary objectivesSuboptimal response ratesEvolving treatment paradigmCell lung cancerLung cancer managementTraditional open surgeryInfluence treatment strategiesStudy's secondary objectivePatient-reported outcomesNational benchmarksOpen surgeryProcess of care indicatorsRisk-adjusted outcomesTreatment paradigmNSCLC treatmentCancer managementFollow-upMA14.13 Analysis of Lung Cancer-Specific Patient-Reported Outcome Measures (PROMs): Results from the PRO4All Project
Servetto A, Malandrini F, Meregaglia M, Valsecchi A, Bennati C, Giovanardi F, Pinto C, Di Maio M, Ciani O. MA14.13 Analysis of Lung Cancer-Specific Patient-Reported Outcome Measures (PROMs): Results from the PRO4All Project. Journal Of Thoracic Oncology 2024, 19: s115-s116. DOI: 10.1016/j.jtho.2024.09.207.Peer-Reviewed Original ResearchBreast-cancer specific comprehensive archive of Patient-Reported Outcome Measures (PROMs) for clinical research and clinical practice in oncology: Results from the PRO4All project
Valsecchi A, Giovanardi F, Malandrini F, Meregaglia M, Servetto A, Bennati C, Pinto C, Di Maio M, Ciani O. Breast-cancer specific comprehensive archive of Patient-Reported Outcome Measures (PROMs) for clinical research and clinical practice in oncology: Results from the PRO4All project. The Breast 2024, 78: 103817. PMID: 39362075, DOI: 10.1016/j.breast.2024.103817.Peer-Reviewed Original ResearchPatient-reported outcome measuresMinimum clinically important differencePatient-reported outcomesOutcome measuresBreast cancerRecall periodInclusion of patient-reported outcomesDelivery of carePatient-centered approachClinically important differenceClinical researchPhysical functionOutcome domainsOutcome classificationImportant differenceSelf-reportOncology clinical trialsQuestionnaireEvaluation of treatmentQuestionnaire descriptionsPublished reviewsClinical practiceOncologyItemsBC patientsArtificial-Intelligence Cloud-Based Platform to Support Shared Decision-Making in the Locoregional Treatment of Breast Cancer: Protocol for a Multidimensional Evaluation Embedded in the CINDERELLA Clinical Trial
Borsoi L, Listorti E, Ciani O. Artificial-Intelligence Cloud-Based Platform to Support Shared Decision-Making in the Locoregional Treatment of Breast Cancer: Protocol for a Multidimensional Evaluation Embedded in the CINDERELLA Clinical Trial. PharmacoEconomics - Open 2024, 8: 945-959. PMID: 39264499, PMCID: PMC11499581, DOI: 10.1007/s41669-024-00519-1.Peer-Reviewed Original ResearchBreast cancer patientsBackgroundShared decision-makingBreast cancer careCloud-based approachPatient decision aidsMultidimensional evaluationCloud-based platformReduce decision regretCost-utility analysisCancer patientsCancer carePatient-level dataHealthcare professionalsArtificial-intelligenceMobile applicationsPersonalized contentDecision regretCountry-specific unit costsFocus groupsLocoregional treatmentPatient questionnaireDecision aidPatient valuationsReal-world settingsWeb platformSurrogate End Points in Trials—SPIRIT and CONSORT Extensions
Taylor R, Manyara A, Ross J, Ciani O. Surrogate End Points in Trials—SPIRIT and CONSORT Extensions. JAMA 2024, 332: 1340-1342. PMID: 39102315, DOI: 10.1001/jama.2024.15219.Peer-Reviewed Original ResearchSample size in multistakeholder Delphi surveys: at what minimum sample size do replicability of results stabilize?
Manyara A, Purvis A, Ciani O, Collins G, Taylor R. Sample size in multistakeholder Delphi surveys: at what minimum sample size do replicability of results stabilize? Journal Of Clinical Epidemiology 2024, 174: 111485. PMID: 39069013, DOI: 10.1016/j.jclinepi.2024.111485.Peer-Reviewed Original ResearchDelphi surveyCONSORT-SPIParticipant characteristicsReplication of resultsParticipant dataSample sizeCore outcomePsychological interventionsSurvey itemsIntervention trialsDelphi studyBurn careIndividual stakeholder groupsRandom subsampleParticipantsSubgroup analysisStakeholder groupsMultistakeholderSurveyEffect of increasing sample sizeMedian numberItemsSubsampleReduced variabilityCareTransparent and complete reporting of surrogate endpoints in trials: the SPIRIT-Surrogate and CONSORT-Surrogate extensions
Manyara A, Ciani O, Taylor R, Group S. Transparent and complete reporting of surrogate endpoints in trials: the SPIRIT-Surrogate and CONSORT-Surrogate extensions. The Lancet 2024, 404: 322-324. PMID: 39004089, DOI: 10.1016/s0140-6736(24)01306-0.Peer-Reviewed Original ResearchReporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration
Manyara A, Davies P, Stewart D, Weir C, Young A, Blazeby J, Butcher N, Bujkiewicz S, Chan A, Dawoud D, Offringa M, Ouwens M, Hróbjartsson A, Amstutz A, Bertolaccini L, Bruno V, Devane D, Faria C, Gilbert P, Harris R, Lassere M, Marinelli L, Markham S, Powers J, Rezaei Y, Richert L, Schwendicke F, Tereshchenko L, Thoma A, Turan A, Worrall A, Christensen R, Collins G, Ross J, Taylor R, Ciani O. Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration. The BMJ 2024, 386: e078524. PMID: 38981645, PMCID: PMC11231881, DOI: 10.1136/bmj-2023-078524.Peer-Reviewed Original ResearchConceptsRandomised controlled trial reportsTrial reportsRandomised controlled trialsControlled trial reportsIntervention treatment effectsResearch wasteTrial findingsTreatment effectsControlled trialsTarget outcomesChecklistAdequate informationSurrogate endpointsInterventionCONSORTItemsTrialsImprove transparencyHarmReportsGuidelinesOutcomesEndpointReporting of surrogate endpoints in randomised controlled trial protocols (SPIRIT-Surrogate): extension checklist with explanation and elaboration
Manyara A, Davies P, Stewart D, Weir C, Young A, Blazeby J, Butcher N, Bujkiewicz S, Chan A, Dawoud D, Offringa M, Ouwens M, Hróbjartsson A, Amstutz A, Bertolaccini L, Bruno V, Devane D, Faria C, Gilbert P, Harris R, Lassere M, Marinelli L, Markham S, Powers J, Rezaei Y, Richert L, Schwendicke F, Tereshchenko L, Thoma A, Turan A, Worrall A, Christensen R, Collins G, Ross J, Taylor R, Ciani O. Reporting of surrogate endpoints in randomised controlled trial protocols (SPIRIT-Surrogate): extension checklist with explanation and elaboration. The BMJ 2024, 386: e078525. PMID: 38981624, PMCID: PMC11231880, DOI: 10.1136/bmj-2023-078525.Peer-Reviewed Original ResearchConceptsTrial protocolRandomised controlled trial protocolTarget outcomesReduce research wasteStandard Protocol ItemsRandomised controlled trialsIntervention effectsProtocol ItemsInterpretation of findingsResearch wasteImprove reportingPrimary outcome(sIntervention trialsControlled trialsChecklistSurrogate endpointsInterventionItemsIncreasing callsTrialsGuidelinesOutcomesLimited informationOutcome(sHarm