2023
Association of lesion location with post-stroke depression in China: a systematic review and meta-analysis.
Luo X, Fang W, Ji J, Zhang Y, Garcia-Milian R, Wang Z, Tan Y, Wang S, Wang X, Guo X, Luo X. Association of lesion location with post-stroke depression in China: a systematic review and meta-analysis. EC Psychology And Psychiatry 2023, 12: 34-45. PMID: 36913221, PMCID: PMC9997510.Peer-Reviewed Original ResearchPost-stroke depressionIncidence of PSDType of strokeCerebral cortexLesion locationOccurrence of PSDBrain lesion locationLeft hemisphereMental health conditionsDifferent brain regionsHemorrhagic strokeChinese patientsHigh riskAnterior cortexPSD incidenceSystematic reviewBrain regionsPSD occurrenceStrokePosterior cortexCortexHealth conditionsSystematic searchRight hemisphereIncidence
2016
Resting-State Functional Connectivity of the Basal Nucleus of Meynert in Cigarette Smokers: Dependence Level and Gender Differences
Zhang S, Hu S, Fucito LM, Luo X, Mazure CM, Zaborszky L, Li CR. Resting-State Functional Connectivity of the Basal Nucleus of Meynert in Cigarette Smokers: Dependence Level and Gender Differences. Nicotine & Tobacco Research 2016, 19: 452-459. PMID: 27613921, PMCID: PMC6074817, DOI: 10.1093/ntr/ntw209.Peer-Reviewed Original ResearchConceptsSupplementary motor areaCigarette smokersCholinergic systemCigarette smokingFemale smokersMotor areaBasal nucleusFunctional connectivityResting-state functional connectivityGender-matched nonsmokersWhole-brain functional connectivityNicotine dependence scoresBilateral anterior insulaNicotinic acetylcholine receptorsPosterior cingulate cortexCurrent smokersMale smokersCerebral cortexCholinergic projectionsMultiple imaging modalitiesBasal forebrainGreater negative connectivitySex-specific differencesSmokersFagerström TestGlutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury
Cao Y, Gao Y, Xu S, Bao J, Lin Y, Luo X, Wang Y, Luo Q, Jiang J, Neale JH, Zhong C. Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury. BMC Neuroscience 2016, 17: 15. PMID: 27091009, PMCID: PMC4836105, DOI: 10.1186/s12868-016-0251-1.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryWild-type miceBrain injuryKnockout miceNeuroprotective efficacyType miceImpact injuryOxidative stressCortical impact injuryInjury-induced increaseBcl-2/Bax ratioGene knockout miceGlutathione peroxidase activityCerebral cortexCortical apoptosisKO miceCytosolic cytochrome c levelsConclusionsThese dataN-acetylaspartylglutamateSynaptic releaseTUNEL-positive nucleiAnimal modelsExtracellular levelsCytochrome c levelsGlutathione levelsAssociation of catechol-O-methyltransferase Val108/158 Met genetic polymorphism with schizophrenia, P50 sensory gating, and negative symptoms in a Chinese population
Mao Q, Tan Y, Luo X, Tian L, Wang Z, Tan S, Chen S, Yang G, An H, Yang F, Zhang X. Association of catechol-O-methyltransferase Val108/158 Met genetic polymorphism with schizophrenia, P50 sensory gating, and negative symptoms in a Chinese population. Psychiatry Research 2016, 242: 271-276. PMID: 27315458, DOI: 10.1016/j.psychres.2016.04.029.Peer-Reviewed Original ResearchConceptsPCR-restriction fragment length polymorphismSchizophrenic patientsP50 deficitsNegative symptomsChinese populationNegative Syndrome ScaleRisk of schizophreniaSymptoms of schizophreniaP50 sensory gatingVal allele carriersHan Chinese populationRole of COMTCerebral cortexClinical symptomatologyHealthy controlsNegative subscoreAllele carriersMetS individualsMet/Met individualsControl groupSensory gatingSyndrome ScaleGenotype distributionP50 gatingSchizophrenic subjects