2020
Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia
Sahbaz C, Zibandey N, Kurtulmus A, Duran Y, Gokalp M, Kırpınar I, Sahin F, Guloksuz S, Akkoc T. Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia. Psychopharmacology 2020, 237: 1861-1871. PMID: 32221694, DOI: 10.1007/s00213-020-05504-0.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsRegulatory T cellsHealthy controlsT cellsIL-17AIL-6Smoking status-matched healthy controlsCulture supernatant levelsT cell percentageTh1/Th2Levels of Foxp3Blood mononuclear cellsBody mass indexImmune imbalanceTreg percentageMass indexProinflammatory cytokinesMethodsForty patientsMononuclear cellsPlasma levelsProinflammatory responseSupernatant levelsCell percentageResultsIn comparisonArray kit
2010
Cytokine levels in euthymic bipolar patients
Guloksuz S, Cetin E, Cetin T, Deniz G, Oral E, Nutt D. Cytokine levels in euthymic bipolar patients. Journal Of Affective Disorders 2010, 126: 458-462. PMID: 20537397, DOI: 10.1016/j.jad.2010.04.027.Peer-Reviewed Original ResearchConceptsEuthymic bipolar patientsBipolar patientsCytokine levelsHealthy controlsBipolar disorderDepressive episodeLithium monotherapyIL-10 levelsIL-4 levelsSerum cytokine levelsPro-inflammatory stateEffects of medicationNeuro-immune modulationTerms of agePatients 16Cytokine profileCytokine productionPresent studyIL-2IL-4IL-5Healthy volunteersPsychiatric disordersPatientsFlow cytometry