The Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments
Guloksuz S, Rutten B, Pries L, Have M, de Graaf R, van Dorsselaer S, Klingenberg B, van Os J, Ioannidis J, Group T. The Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments. Schizophrenia Bulletin 2018, 44: 1175-1179. PMID: 30169883, PMCID: PMC6192470, DOI: 10.1093/schbul/sby118.Peer-Reviewed Original ResearchConceptsMental health outcomesHealth outcomesNetherlands Mental Health SurveyMental Health SurveyPre-specified analysis planFalsification endpointsModifiable factorsSources of heterogeneityHealth SurveyIntervention effectsSelective reportingAnalysis planP-valueOutcomesEffect sizeVibration of effectsAnalytical planSame outcomeDifferent studiesExploratory analysisExposureStudy 2 dataP-value threshold