Glutathione S-transferase gene polymorphisms and air pollution as interactive risk factors for asthma in a multicentre Italian field study: A preliminary study
Piacentini S, Polimanti R, Moscatelli B, Re MA, Fuciarelli R, Manfellotto D, Fuciarelli M. Glutathione S-transferase gene polymorphisms and air pollution as interactive risk factors for asthma in a multicentre Italian field study: A preliminary study. Annals Of Human Biology 2010, 37: 427-439. PMID: 20367187, DOI: 10.3109/03014461003636419.Peer-Reviewed Original ResearchConceptsGlutathione S-transferase (GST) gene polymorphismsImpairs pulmonary functionCommon chronic diseasesCase-control studyGlutathione S-transferaseGenotyping of GSTM1Interactive risk factorsFrequency of GSTA1Asthmatic patientsPulmonary functionAsthma developmentRisk factorsChronic diseasesGSTT1 genotypeGSTP1 polymorphismsPCR-RFLP methodAsthma diseaseGene-environment interactionsControl groupGene polymorphismsGSTT1 genesPossible associationReactive oxygen speciesProtection of cellsAsthma