2015
GSTA1 gene variation associated with gestational hypertension and its involvement in pregnancy-related pathogenic conditions
Iorio A, Spinelli M, Polimanti R, Lorenzi F, Valensise H, Manfellotto D, Fuciarelli M. GSTA1 gene variation associated with gestational hypertension and its involvement in pregnancy-related pathogenic conditions. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2015, 194: 34-37. PMID: 26321410, DOI: 10.1016/j.ejogrb.2015.08.006.Peer-Reviewed Original ResearchConceptsGestational hypertensionOdds ratioRisk of GHPregnancy-related conditionsT gene polymorphismGlutathione S-transferaseDominant genetic modelPhase II enzymesCase-control populationGH womenCardiovascular complicationsGSTA1 polymorphismsPregnant womenSignificant allelic differencesRFLP-PCR techniqueItalian patientsGenetic predispositionGene polymorphismsSignificant associationT variantDisease riskExogenous toxic compoundsGSTA1 genePhase IGSTA1
2012
Glutathione S-transferase genes and the risk of recurrent miscarriage in Italian women
Polimanti R, Piacentini S, Lazzarin N, Vaquero E, Re MA, Manfellotto D, Fuciarelli M. Glutathione S-transferase genes and the risk of recurrent miscarriage in Italian women. Fertility And Sterility 2012, 98: 396-400. PMID: 22633257, DOI: 10.1016/j.fertnstert.2012.05.003.Peer-Reviewed Original ResearchConceptsRecurrent miscarriageT alleleRisk of RMGSTA1 geneGlutathione S-transferaseGSTM1 variantsPregnancy complicationsRM riskMAIN OUTCOMEGST polymorphismsRM groupNull genotypeControl groupGSTT1 genesSignificant associationGSTP1 geneBuccal cellsItalian womenDifferent genetic modelsSingle nucleotide polymorphismsWomenGSTA1MiscarriageRiskGenetic association studies