2024
Understanding Cognitive Behavioral Therapy for Psychosis Through the Predictive Coding Framework
Sheffield J, Brinen A, Feola B, Heckers S, Corlett P. Understanding Cognitive Behavioral Therapy for Psychosis Through the Predictive Coding Framework. Biological Psychiatry Global Open Science 2024, 4: 100333. PMID: 38952435, PMCID: PMC11215207, DOI: 10.1016/j.bpsgos.2024.100333.Peer-Reviewed Original ResearchCognitive behavioral therapyPersecutory delusionsBehavioral therapyMaintenance of delusionsSymptoms of psychosisAssociative learning modelsCognitive-behavioral interventionsPrediction error signalsLevels of information processingPredictive coding frameworkHierarchical predictive codingPredictive codingPsychotic disordersPsychological treatmentCognitive neurosciencePsychological processesCBTpPsychosisDelusionsBelief updatingInformation processingAlternative beliefsNeuroscienceProcess theoryComputational neuroscienceLongitudinal Associations Between Belief Updating and Delusions in Individuals Recovering From an Acute Psychotic Episode
Sheffield J, Hall L, Vandekar S, Liu J, Woodward N, Heckers S, Corlett P. Longitudinal Associations Between Belief Updating and Delusions in Individuals Recovering From an Acute Psychotic Episode. Biological Psychiatry 2024, 95: s66-s67. DOI: 10.1016/j.biopsych.2024.02.164.Peer-Reviewed Original ResearchDifferent learning aberrations relate to delusion-like beliefs with different contents
Rossi-Goldthorpe R, Silverstein S, Gold J, Schiffman J, Waltz J, Williams T, Powers A, Woods S, Zinbarg R, Mittal V, Ellman L, Strauss G, Walker E, Levin J, Castiello S, Kenney J, Corlett P. Different learning aberrations relate to delusion-like beliefs with different contents. Brain 2024, 147: 2854-2866. PMID: 38637303, PMCID: PMC11292907, DOI: 10.1093/brain/awae122.Peer-Reviewed Original ResearchProbabilistic reversal learningDelusion-like beliefsProbabilistic reversal learning taskBlocked cueControl cuesBelief convictionBlock taskClinical high-risk statusKamin blocking taskSymptom-specific effectsPrediction error accountLevels of paranoiaIntact learningAberrant learningKamin blockingParanoid individualsPersecutory delusionsCue presentationReversal learningPredicting psychosisCognitive tasksBehavioral resultsDecreased learningDelusionsParanoiaImagination, Agency, and Predictive Processing
Corlett P. Imagination, Agency, and Predictive Processing. 2024, 60-78. DOI: 10.1093/oso/9780198872221.003.0004.Peer-Reviewed Original ResearchPredictive processing theoryTheories of delusionsPredictive coding theorySensory inputDelusion formationSource monitoringProcess theoryDelusionsMediated learningHallucinationsConscious experienceImaginative processesReality perceptionPrediction processNeurocomputer architectureBeliefsPerceptionDysfunctionDelusions and the Predictive Mind
Bongiorno F, Corlett P. Delusions and the Predictive Mind. Australasian Journal Of Philosophy 2024, 102: 1014-1029. DOI: 10.1080/00048402.2023.2293825.Peer-Reviewed Original Research
2023
Relationships between cognitive biases, decision-making, and delusions
Sheffield J, Smith R, Suthaharan P, Leptourgos P, Corlett P. Relationships between cognitive biases, decision-making, and delusions. Scientific Reports 2023, 13: 9485. PMID: 37301915, PMCID: PMC10257713, DOI: 10.1038/s41598-023-36526-1.Peer-Reviewed Original ResearchConceptsDelusional ideationDelusional thinkingCognitive biasesDistinct cognitive processesSelf-reported dataCognitive processesProbabilistic reversalUnique varianceComputational mechanismsEvidence integrationPsychosis spectrumMultiple measuresProportion of varianceParanoiaRandom explorationIdeationThinkingTaskBiasesMeasuresVarianceDelusionsJTCIndependent studiesRelationshipUsing dimensionality-reduction techniques to understand the organization of psychotic symptoms in persistent psychotic illness and first episode psychosis
Fleming L, Lemonde A, Benrimoh D, Gold J, Taylor J, Malla A, Joober R, Iyer S, Lepage M, Shah J, Corlett P. Using dimensionality-reduction techniques to understand the organization of psychotic symptoms in persistent psychotic illness and first episode psychosis. Scientific Reports 2023, 13: 4841. PMID: 36964175, PMCID: PMC10039017, DOI: 10.1038/s41598-023-31909-w.Peer-Reviewed Original ResearchConceptsHallucinations/delusionsFirst-episode psychosisFirst-episode psychosis participantsEarly intervention programsPathophysiological mechanismsUnderlying pathophysiologyEpisode psychosisPsychotic illnessPsychotic symptomsPsychotic disordersSchizoaffective disorderAuditory hallucinationsPositive symptomsHallucination severityNegative symptomsSymptomsDisorganization symptomsIntervention programsHallucinationsIllnessPsychosis participantsPsychosisDelusionsDisordersParticipants
2020
T70. DUAL-PROCESS THEORY, CONFLICT PROCESSING, AND DELUSIONAL BELIEF
Bronstein M, Pennycook G, Joormann J, Corlett P, Cannon T. T70. DUAL-PROCESS THEORY, CONFLICT PROCESSING, AND DELUSIONAL BELIEF. Schizophrenia Bulletin 2020, 46: s258-s258. PMCID: PMC7234109, DOI: 10.1093/schbul/sbaa029.630.Peer-Reviewed Original ResearchDual-process theoryReasoning biasesDelusional individualsAnalytic reasoningConflict processingProcessing deficitsDual-process perspectiveDual-process reasoningMaintenance of delusionsConflict detectionCognitive biasesDelusion formationNeurocognitive responsesDisconfirmatory evidenceDelusional beliefsPresence of conflictAnalytic thinkingIntuitive systemDeficitsAdditional engagementBiasesFuture researchDelusionsRecent theoriesCausal role
2018
Delusions and Prediction Error
Corlett P. Delusions and Prediction Error. 2018, 35-66. DOI: 10.1007/978-3-319-97202-2_2.Peer-Reviewed Original ResearchAberrant prediction errorsPrediction error responsesPrediction errorCognitive neuroscienceParsimonious accountNeural mechanismsError responsesProblem of beliefProminent theoriesPredictive codingNovel predictionsError accountsDelusionsBridging TheoryPhenomenological dataBeliefsAdaptive fitnessNeuroscienceSingle factorTheoryBrainMindErrorAccountPrediction
2012
Delusions
Corlett P. Delusions. 2012, 667-673. DOI: 10.1016/b978-0-12-375000-6.00126-9.Peer-Reviewed Original Research
2010
Toward a neurobiology of delusions
Corlett PR, Taylor JR, Wang X, Fletcher PC, Krystal JH. Toward a neurobiology of delusions. Progress In Neurobiology 2010, 92: 345-369. PMID: 20558235, PMCID: PMC3676875, DOI: 10.1016/j.pneurobio.2010.06.007.Peer-Reviewed Original ResearchConceptsFundamental brain mechanismsFronto-striatal circuitsTerms of cognitionPsychological processesBrain mechanismsComputational mechanismsCortical hierarchyPrediction errorSocial learningParietal cortexExternal worldBrain circuitsNeurobiological abnormalitiesNeurobiology of delusionsBrain functionHierarchical predictionBodily agencyDelusionsMemoryReinforcement learningPerceptionMental illnessTranslational understandingLearningCognition
2009
Why Do Delusions Persist?
Corlett PR, Krystal JH, Taylor JR, Fletcher PC. Why Do Delusions Persist? Frontiers In Human Neuroscience 2009, 3: 12. PMID: 19636384, PMCID: PMC2713737, DOI: 10.3389/neuro.09.012.2009.Peer-Reviewed Original Research
2007
Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions
Corlett PR, Murray GK, Honey GD, Aitken MR, Shanks DR, Robbins TW, Bullmore ET, Dickinson A, Fletcher PC. Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions. Brain 2007, 130: 2387-2400. PMID: 17690132, PMCID: PMC3838942, DOI: 10.1093/brain/awm173.Peer-Reviewed Original ResearchConceptsDelusion formationDelusional beliefsPrediction error processingPrediction-error signallingPrediction error signalsAttentional allocationAssociative accountMaladaptive beliefsError processingAssociative learningNeurobiological theoriesBrain responsesCortex responsesIndividual's propensityBelief formationDelusionsBeliefsPrediction errorExtent of disruptionProcessingFMRILearningPsychosisExpectancyIndividualsFrom prediction error to psychosis: ketamine as a pharmacological model of delusions
Corlett PR, Honey GD, Fletcher PC. From prediction error to psychosis: ketamine as a pharmacological model of delusions. Journal Of Psychopharmacology 2007, 21: 238-252. PMID: 17591652, DOI: 10.1177/0269881107077716.Peer-Reviewed Original ResearchConceptsDelusion formationAssociative learning processesPrediction error signalsDevelopment of delusionsFormation of delusionsPre-psychotic periodAttentional disruptionAttentional disturbancesNeuropsychiatric modelsNeurobiological systemsPrediction errorExperience resultsLearning processIrrelevant detailsDelusionsError signalDrug ketaminePsychosisNumerous associationsPsychotic statesPerceptExpectationsPharmacological modelStimuliSymptom evolution