Featured Publications
Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila
McCurdy LY, Sareen P, Davoudian PA, Nitabach MN. Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila. Nature Communications 2021, 12: 1115. PMID: 33602917, PMCID: PMC7893153, DOI: 10.1038/s41467-021-21388-w.Peer-Reviewed Original ResearchConceptsDopaminergic neuronsCholinergic neuronsNeural circuit mechanismsCholinergic relayDopaminergic mechanismsSynaptic excitationSynaptic reconstructionSynaptic inputsVivo functional imagingCircuit mechanismsNeuronsAversive memoryFunctional imagingOdor responsesAversive outcomesReduced activationSuch activationCircuit motifsActivationOutcomesElectric shock punishmentSensory cuesUnexpected omissionShock punishmentBehavioral analysis
2013
Anatomical Coupling between Distinct Metacognitive Systems for Memory and Visual Perception
McCurdy L, Maniscalco B, Metcalfe J, Liu K, de Lange F, Lau H. Anatomical Coupling between Distinct Metacognitive Systems for Memory and Visual Perception. Journal Of Neuroscience 2013, 33: 1897-1906. PMID: 23365229, PMCID: PMC4696871, DOI: 10.1523/jneurosci.1890-12.2013.Peer-Reviewed Original ResearchConceptsMetacognitive efficiencyFrontal polar regionsGray matter volumeMetacognitive systemKinds of metacognitionMatter volumeDistinct brain structuresVoxel-based morphometry analysisMemory taskBehavioral correlationsMetacognitive mechanismsMetacognitive tasksModel comparison analysisMemory processingPrecuneus volumeVisual perceptionAnatomical couplingStructural covariationPsychophysical measuresPrecuneus regionsMetacognitionHuman brainBrain structuresMorphometry analysisTask