2011
Integrated Optogenetic and Electrophysiological Dissection of Local Cortical Circuits In Vivo
Cardin J. Integrated Optogenetic and Electrophysiological Dissection of Local Cortical Circuits In Vivo. Neuromethods 2011, 67: 339-355. DOI: 10.1007/7657_2011_23.Peer-Reviewed Original Research
2009
Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro
Cao R, Higashikubo B, Cardin J, Knoblich U, Ramos R, Nelson M, Moore C, Brumberg J. Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro. Cleveland Clinic Journal Of Medicine 2009, 76: s80-s85. PMID: 19380306, PMCID: PMC4406396, DOI: 10.3949/ccjm.76.s2.16.Peer-Reviewed Original ResearchConceptsBlood volumeApplication of pinacidilWhole-cell recordingsLocal blood volumeFunctional hyperemiaVascular dilationNeocortical slicesAnesthetized ratsAwake miceSmooth muscleSelective agonistPinacidilImpact of hemodynamicsIntrinsic modulatorHyperemiaNeural activityVasodilationNeuronsVivoBiophysical propertiesNeural systemsHemodynamicsAgonistsNeocortexRats
2008
Cellular Mechanisms Underlying Stimulus-Dependent Gain Modulation in Primary Visual Cortex Neurons In Vivo
Cardin JA, Palmer LA, Contreras D. Cellular Mechanisms Underlying Stimulus-Dependent Gain Modulation in Primary Visual Cortex Neurons In Vivo. Neuron 2008, 59: 150-160. PMID: 18614036, PMCID: PMC2504695, DOI: 10.1016/j.neuron.2008.05.002.Peer-Reviewed Original ResearchConceptsSynaptic activationPrimary visual cortex neuronsCat primary visual cortexVisual cortex neuronsCellular mechanismsPrimary visual cortexNeuronal gainBackground synaptic activityVisual stimuliPostsynaptic effectsCortex neuronsIntracellular recordingsSynaptic activitySynaptic inputsVisual cortexInput resistanceVisual stimulationGain modulationSustained changesVivoSensory contextMembrane potentialNeuronal phenomenaActivationModulation