2021
Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues
Gee DG, Cohodes EM. Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues. Current Directions In Psychological Science 2021, 30: 376-383. PMID: 34675455, PMCID: PMC8528226, DOI: 10.1177/09637214211015673.Peer-Reviewed Original ResearchCorticolimbic circuitryEmotional reactivitySensitive periodCaregiver influenceExternal regulationChildren's emotional reactivityEarly sensitive periodPeriod of plasticityEarly life adversitySafety cuesEmotion regulationNeurobiological mechanismsCaregiving experiencesLife adversityIntervention effortsCaregiver behaviorBehavioral developmentAffective behaviorBiological embeddingHuman researchPowerful influenceAdversityCaregiver inputCaregiversCircuitry
2020
Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
Cohodes EM, Kitt ER, Baskin‐Sommers A, Gee DG. Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology 2020, 63: 153-172. PMID: 32227350, DOI: 10.1002/dev.21969.Peer-Reviewed Original ResearchConceptsEarly life stressFrontolimbic circuitryStress exposurePhysical health problemsEffects of stressCircuit maturationGlucocorticoid receptorHealth problemsMajority of studiesMental healthExposure influencePsychobiological effectsDimensional approachEarly experienceDifferential outcomesOutcomesSubsequent vulnerabilityRiskVast heterogeneityExposureInnervationCircuitryBrainSeverityCaregivers
2014
Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence
Gee DG, Gabard-Durnam L, Telzer EH, Humphreys KL, Goff B, Shapiro M, Flannery J, Lumian DS, Fareri DS, Caldera C, Tottenham N. Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence. Psychological Science 2014, 25: 2067-2078. PMID: 25280904, PMCID: PMC4377225, DOI: 10.1177/0956797614550878.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryMaternal bufferingMaternal stimuliAmygdala-prefrontal connectivityMature connectivityAmygdala reactivityPotential mechanismsMaternal modulationChildhoodMother-child relationshipNeural mechanismsSensitive periodChildrenCaregiversMaternal influenceRegulatory influenceAdolescenceStimuliBehavioral regulationNeurocircuitryCircuitry