Increased pituitary and adrenal reactivity in premenopausal women with posttraumatic stress disorder
Rasmusson A, Lipschitz D, Wang S, Hu S, Vojvoda D, Bremner J, Southwick S, Charney D. Increased pituitary and adrenal reactivity in premenopausal women with posttraumatic stress disorder. Biological Psychiatry 2001, 50: 965-977. PMID: 11750893, DOI: 10.1016/s0006-3223(01)01264-1.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAdrenal axis regulationAdrenocorticotropic hormonePremenopausal womenPosttraumatic stress disorder subjectsPosttraumatic stress disorder groupCortisol responseStress disorderAxis regulationCortisol levelsUrinary free cortisol excretionDisorder subjectsUrinary free cortisol measurementChronic posttraumatic stress disorderDisorder groupAdrenocorticotropin stimulation testPeak cortisol responseMenstrual cycle phaseBaseline cortisol levelsGreater cortisol responseBaseline adrenocorticotropic hormoneLH surgeExogenous corticotropinPsychotropic medicationsStimulation test