2005
Effects of Cigarette Smoking on Spatial Working Memory and Attentional Deficits in Schizophrenia: Involvement of Nicotinic Receptor Mechanisms
Sacco KA, Termine A, Seyal A, Dudas MM, Vessicchio JC, Krishnan-Sarin S, Jatlow PI, Wexler BE, George TP. Effects of Cigarette Smoking on Spatial Working Memory and Attentional Deficits in Schizophrenia: Involvement of Nicotinic Receptor Mechanisms. JAMA Psychiatry 2005, 62: 649-659. PMID: 15939842, DOI: 10.1001/archpsyc.62.6.649.Peer-Reviewed Original ResearchConceptsVisuospatial working memoryWorking memoryAttentional deficitsCognitive deficitsOvernight abstinenceContinuous Performance Test scoresSpatial working memoryOutpatient mental health centersPerformance test scoresCognitive enhancementCPT performanceNeuropsychological assessmentSmoking reinstatementTobacco cravingControl smokersTest scoresCounterbalanced mannerMental health centersCognitive impairmentReinstatementSubjective effectsNicotine dependenceCigarette smokingDeficitsNicotinic receptor mechanisms
2004
Neuropsychological deficits are associated with smoking cessation treatment failure in patients with schizophrenia
Dolan SL, Sacco KA, Termine A, Seyal AA, Dudas MM, Vessicchio JC, Wexler BE, George TP. Neuropsychological deficits are associated with smoking cessation treatment failure in patients with schizophrenia. Schizophrenia Research 2004, 70: 263-275. PMID: 15329302, DOI: 10.1016/j.schres.2004.01.006.Peer-Reviewed Original ResearchConceptsNon-psychiatric control smokersTreatment failureStroop Color-Word TestContinuous Performance TestNeuropsychological deficitsControl smokersWisconsin Card Sorting TestPlacebo-controlled trialAtypical antipsychotic treatmentCessation treatmentAntipsychotic treatmentCessation interventionsCigarette smokingDepressive symptomsPharmacological agentsColor-Word TestSmokingNeuropsychological assessmentNeuropsychological performanceCard Sorting TestVisuospatial Working Memory TaskGreater deficitsPreliminary dataSmokersPatients