2005
Special education needs of children with newly diagnosed epilepsy.
Berg A, Smith S, Frobish D, Levy S, Testa F, Beckerman B, Shinnar S. Special education needs of children with newly diagnosed epilepsy. Developmental Medicine & Child Neurology 2005, 47: 749-53. PMID: 16225738, DOI: 10.1017/s001216220500157x.Peer-Reviewed Original ResearchConceptsOnset of seizuresFirst seizureMean ageIntact childrenProspective community-based studyRemote symptomatic etiologyOnset of epilepsyCommunity-based studyTime of interviewYears 10 monthsChildren's mean ageYears 11 monthsInitiation of servicesSymptomatic etiologyChildhood epilepsyEpileptic encephalopathyService useEpilepsyTiming of servicesSeizuresCognitive abnormalitiesFormer groupChildrenAgeEtiology
2004
Status epilepticus after the initial diagnosis of epilepsy in children
Berg A, Shinnar S, Testa F, Levy S, Frobish D, Smith S, Beckerman B. Status epilepticus after the initial diagnosis of epilepsy in children. Neurology 2004, 63: 1027-1034. PMID: 15452294, DOI: 10.1212/01.wnl.0000138425.54223.dc.Peer-Reviewed Original ResearchConceptsStatus epilepticusInitial diagnosisSymptomatic etiologyProspective community-based cohort studyYounger ageCommunity-based cohort studyCox proportional hazards modelPrevious status epilepticusSubsequent status epilepticusKaplan-Meier analysisProportional hazards modelDiagnosis of epilepsyHistory of statusAbortive therapyCohort studyEpilepsy syndromesMedical recordsFirst episodeEpilepticusHigh riskHazards modelChi2 testEpilepsyDiagnosisEtiology
2003
Hypothalamic hamartomas: seven cases and review of the literature
Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy & Behavior 2003, 4: 246-258. PMID: 12791326, DOI: 10.1016/s1525-5050(03)00086-6.Peer-Reviewed Original ResearchConceptsSessile lesionsPrecocious pubertyDifferent surgical optionsGamma Knife surgeryRare developmental lesionIntrinsic epileptogenicityGelastic seizuresGelastic epilepsySeizure typesPartial resectionSurgical optionsHypothalamic hamartomaOpen surgeryTranscallosal approachClinical aspectsSubtemporal approachIntraventricular componentDevelopmental lesionsCognitive declineLesionsAvailable evidenceResectionSurgerySeizuresSubsequent development
2002
Corrections to: Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy
Berg A, Shinnar S, Levy S, Testa F, Smith‐Rapaport S, Beckerman B, Ebrahimi N. Corrections to: Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy. Epilepsia 2002, 43: 207-208. DOI: 10.1046/j.1528-1157.2002.err432.x.Peer-Reviewed Original Research
2001
Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy
Berg A, Shinnar S, Levy S, Testa F, Smith‐Rapaport S, Beckerman B, Ebrahimi N. Two‐Year Remission and Subsequent Relapse in Children with Newly Diagnosed Epilepsy. Epilepsia 2001, 42: 1553-1562. PMID: 11879366, DOI: 10.1046/j.1528-1157.2001.21101.x.Peer-Reviewed Original ResearchConceptsEpilepsy syndromesSymptomatic etiologySeizure frequencyMultivariable analysisInitial EEGFamily historyCox proportional hazards modelInitial seizure frequencyRemote symptomatic etiologyTwo-year remissionRecurrence of seizuresPredictors of remissionIdiopathic generalized epilepsyYounger onset ageProportional hazards modelJuvenile myoclonic epilepsyBenign rolandic epilepsySeizure outcomeRemission rateSeizure controlSeizure typesFocal slowingGeneralized epilepsySubsequent relapseEEG slowingEarly development of intractable epilepsy in children
Berg A, Shinnar S, Levy S, Testa F, Smith–Rapaport S, Beckerman B. Early development of intractable epilepsy in children. Neurology 2001, 56: 1445-1452. PMID: 11402099, DOI: 10.1212/wnl.56.11.1445.Peer-Reviewed Original ResearchConceptsInitial seizure frequencyFebrile status epilepticusStatus epilepticusIntractable epilepsyCryptogenic/Seizure frequencyEpilepsy syndromesAbsolute numberChild neurology practiceFocal EEG slowingLocalization-related syndromesNeonatal status epilepticusMultivariable adjustmentEpilepsy guidelinesIdiopathic syndromeUnclassified epilepsyEEG slowingNeurology practiceHigh riskNew therapiesInternational LeagueEpilepsySyndromeEpilepticusEarly useDefining early seizure outcomes in pediatric epilepsy: the good, the bad and the in-between
Berg A, Shinnar S, Levy S, Testa F, Smith-Rapaport S, Beckerman B, Ebrahimi N. Defining early seizure outcomes in pediatric epilepsy: the good, the bad and the in-between. Epilepsy Research 2001, 43: 75-84. PMID: 11137389, DOI: 10.1016/s0920-1211(00)00184-4.Peer-Reviewed Original ResearchConceptsSeizure outcomeThree-level outcomeProspective cohort studyCohort studyEarly remissionPrognostic factorsEarly outcomesPediatric epilepsyWorse outcomesSyndromic groupingIndeterminate groupRemissionTreatment issuesOutcomesChildrenEpilepsyEtiologyMore yearsAssociationAgeYearsIndeterminate outcomeSyndrome
2000
How Well Can Epilepsy Syndromes Be Identified at Diagnosis? A Reassessment 2 Years After Initial Diagnosis
Berg A, Shinnar S, Levy S, Testa F, Smith‐Rapaport S, Beckerman B. How Well Can Epilepsy Syndromes Be Identified at Diagnosis? A Reassessment 2 Years After Initial Diagnosis. Epilepsia 2000, 41: 1269-1275. PMID: 11051121, DOI: 10.1111/j.1528-1157.2000.tb04604.x.Peer-Reviewed Original ResearchConceptsEpilepsy syndromesInitial diagnosisInternational LeagueSymptomatic localization-related epilepsyLennox-Gastaut syndromeLocalization-related epilepsyCohort of childrenDistribution of syndromesEpilepsy guidelinesSeizure disorderWest syndromePediatric epilepsyEpidemiological studiesEpilepsy classificationSyndromeEpilepsyDiagnosisUnrelated syndromesChildrenCohortSignificant changesYearsAdditional evidencePhysiciansCasesNeuroimaging in Children With Newly Diagnosed Epilepsy: A Community-Based Study
Berg A, Testa F, Levy S, Shinnar S. Neuroimaging in Children With Newly Diagnosed Epilepsy: A Community-Based Study. Pediatrics 2000, 106: 527-532. PMID: 10969098, DOI: 10.1542/peds.106.3.527.Peer-Reviewed Original ResearchConceptsFocal EEG abnormalitiesPartial seizuresEpilepsy syndromesEEG abnormalitiesLocalization-related epilepsy syndromesEvaluation of seizuresIdiopathic generalized epilepsyCommunity-based studyForms of epilepsyEvaluation of childrenHalf of childrenMagnetic resonance imagingNeurologic deficitsElectroencephalographic findingsInitial diagnosisCerebral malformationsGeneralized epilepsyCavernous angiomaPediatric epilepsyTomography scanArteriovenous malformationsTuberous sclerosisRelevant abnormalitiesInternational LeagueEpilepsy
1999
Treatment of Newly Diagnosed Pediatric Epilepsy: A Community-Based Study
Berg A, Levy S, Testa F, Shinnar S. Treatment of Newly Diagnosed Pediatric Epilepsy: A Community-Based Study. JAMA Pediatrics 1999, 153: 1267-1271. PMID: 10591304, DOI: 10.1001/archpedi.153.12.1267.Peer-Reviewed Original ResearchConceptsAntiepileptic drugsPediatric epilepsyInitial diagnosisIdiopathic localization-related epilepsyFirst antiepileptic drugTime of diagnosisTreatment of NewlyInitiation of treatmentLocalization-related epilepsySpecific seizure typesCommunity-based studyForms of epilepsyFrequency of treatmentDiagnosis of epilepsyFirst seizureSeizure typesUnprovoked seizuresSodium valproateSpecific medicationsCurrent guidelinesFirst drugInvestigational drugsEpilepsyMonths 90Specific drugsChildhood-onset epilepsy with and without preceding febrile seizures
Berg A, Shinnar S, Levy S, Testa F. Childhood-onset epilepsy with and without preceding febrile seizures. Neurology 1999, 53: 1742-1748. PMID: 10563622, DOI: 10.1212/wnl.53.8.1742.Peer-Reviewed Original ResearchConceptsFebrile seizuresSimple febrile seizuresLocalization-related epilepsyTemporal lobe epilepsyOnset of epilepsyLobe epilepsyPrior febrile seizuresTime of diagnosisChildhood-onset epilepsyComplex febrile seizuresChildhood absence epilepsyCohort of childrenAge-dependent susceptibilityInitial MRIHippocampal atrophyAbsence epilepsyAbsence seizuresDegree relativesFamily historyEpilepsySeizuresChild's epilepsyYounger ageChildrenPositive associationStatus epilepticus in children with newly diagnosed epilepsy
Berg A, Shinnar S, Levy S, Testa F. Status epilepticus in children with newly diagnosed epilepsy. Annals Of Neurology 1999, 45: 618-623. PMID: 10319884, DOI: 10.1002/1531-8249(199905)45:5<618::aid-ana10>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsOccurrence of SEStatus epilepticusClinical characteristicsSubsequent status epilepticusSpecific clinical characteristicsOnset of epilepsyPractices of physiciansDiagnosis of epilepsyProvoked seizuresPrognostic factorsNeurological emergencyPartial seizuresPrevious craniotomyUnprovoked seizuresEpilepsy syndromesPrognostic valueMore episodesHigh riskEpilepsyStandardized interviewYounger ageSeizuresEpilepticusSubstantial minorityChildrenClassification of Childhood Epilepsy Syndromes in Newly Diagnosed Epilepsy: Interrater Agreement and Reasons for Disagreement
Berg A, Levy S, Testa F, Shinnar S. Classification of Childhood Epilepsy Syndromes in Newly Diagnosed Epilepsy: Interrater Agreement and Reasons for Disagreement. Epilepsia 1999, 40: 439-444. PMID: 10219269, DOI: 10.1111/j.1528-1157.1999.tb00738.x.Peer-Reviewed Original ResearchConceptsEpilepsy syndromesInterrater agreementChildhood epilepsy syndromesCommunity-based studyInitial diagnostic assessmentForms of epilepsyCommunity-based sampleNonspecific syndromeILAE classificationPediatric neurologistsEpidemiologic settingsIdentification of syndromesInternational LeagueEpilepsy classificationEpilepsySyndromeDiagnostic assessmentKappa scoresSubstantial proportionChildrenLimited qualitySeizure informationWidespread useNeurologistsNewly Diagnosed Epilepsy in Children: Presentation at Diagnosis
Berg A, Shinnar S, Levy S, Testa F. Newly Diagnosed Epilepsy in Children: Presentation at Diagnosis. Epilepsia 1999, 40: 445-452. PMID: 10219270, DOI: 10.1111/j.1528-1157.1999.tb00739.x.Peer-Reviewed Original ResearchConceptsEpilepsy syndromesFirst seizureAdolescent-onset epilepsyCurrent classification guidelinesRemote symptomatic etiologyTime of diagnosisChildhood-onset epilepsyCommunity-based cohortBenign rolandic epilepsyRelevant medical recordsSymptomatic etiologyAdult neurologistsMedian agePediatric neurologistsPrognostic valueInfantile spasmsGeneralized syndromeMedical recordsChildhood absenceCommon syndromeChild neurologistsClassification of seizuresRolandic epilepsyEpilepsySyndrome
1998
Comparison of Digital and Conventional EEG Interpretation
Levy S, Berg A, Testa F, Novotny E, Chiappa K. Comparison of Digital and Conventional EEG Interpretation. Journal Of Clinical Neurophysiology 1998, 15: 476-480. PMID: 9881918, DOI: 10.1097/00004691-199811000-00004.Peer-Reviewed Original Research
1996
THE EPIDEMIOLOGY OF EPILEPSY Past, Present, and Future
Berg A, Testa F, Levy S, Shinnar S. THE EPIDEMIOLOGY OF EPILEPSY Past, Present, and Future. Neurologic Clinics 1996, 14: 383-398. PMID: 8827178, DOI: 10.1016/s0733-8619(05)70263-2.Peer-Reviewed Original ResearchPredictors of Intractable Epilepsy in Childhood: A Case‐Control Study
Berg A, Levy S, Novotny E, Shinnar S. Predictors of Intractable Epilepsy in Childhood: A Case‐Control Study. Epilepsia 1996, 37: 24-30. PMID: 8603620, DOI: 10.1111/j.1528-1157.1996.tb00507.x.Peer-Reviewed Original ResearchConceptsRemote symptomatic epilepsyCase-control studyIntractable epilepsyStatus epilepticusSymptomatic epilepsyAntiepileptic drugsDifferent antiepileptic drugsFuture prospective studiesRecent cohort studiesMultiple logistic regressionStrongest univariate associationsDiagnosis of epilepsyCohort studyIndependent predictorsInitial diagnosisNeonatal seizuresProspective studyUnivariate associationsEarly predictorEpilepsyLogistic regressionAge rangeSeizuresChildrenDiagnosis
1988
Electroencephalography in AIDS and AIDS-Related Complex
Gabuzda D, Levy S, Chiappa K. Electroencephalography in AIDS and AIDS-Related Complex. Clinical EEG And Neuroscience 1988, 19: 1-6. PMID: 3396199, DOI: 10.1177/155005948801900103.Peer-Reviewed Original ResearchConceptsAbnormal EEGApparent neurologic diseaseUseful diagnostic testCerebral toxoplasmosisCNS lymphomaAIDS dementiaImmunodeficiency syndromeOpportunistic infectionsFocal slowingNeurologic abnormalitiesEEG findingsCognitive dysfunctionNeurologic diseasePsychiatric symptomsPatientsSharp activityAIDSDiagnostic testsCNS processesDementiaEEGEEG recordsToxoplasmosisLymphomaDysfunction
1986
Early Evolution and Incidence of Electroencephalographic Abnormalities in Creutzfeldt-Jakob Disease
Levy S, Chiappa K, Burke C, Young R. Early Evolution and Incidence of Electroencephalographic Abnormalities in Creutzfeldt-Jakob Disease. Journal Of Clinical Neurophysiology 1986, 3: 1-21. PMID: 3512597, DOI: 10.1097/00004691-198601000-00001.Peer-Reviewed Original ResearchConceptsPeriodic sharp wave complexesCreutzfeldt-Jakob diseaseMassachusetts General HospitalClinical courseDiagnosis of CJDFocal neurological abnormalitiesLong clinical courseSharp wave complexesWeeks of onsetClinical therapeutic trialsCertainty of diagnosisBrain biopsyNeuropathological findingsTherapeutic trialsClinical symptomsNeuroradiological findingsRare subtypeEEG findingsElectroencephalographic abnormalitiesFocal myoclonusGeneral HospitalNeurological abnormalitiesWeeks durationCerebrospinal fluidPathological investigation