Sabyasachi Sutradhar, PhD
Associate Research ScientistCards
About
Titles
Associate Research Scientist
Appointments
Molecular Biophysics and Biochemistry
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Calcutta, Physics/Biophysics (2016)
Research
Publications
2026
Phosphatidylinositol-3-phosphate-dependent Klp98A recruitment regulates endosomal flux underlying developmental synaptic remodeling via Rab4
Singh K, Das S, Rai D, Sutradhar S, Sarkar A, Howard J, Ray K. Phosphatidylinositol-3-phosphate-dependent Klp98A recruitment regulates endosomal flux underlying developmental synaptic remodeling via Rab4. Journal Of Cell Science 2026, 139: jcs264782. PMID: 41728866, PMCID: PMC13070254, DOI: 10.1242/jcs.264782.Peer-Reviewed Original ResearchConceptsTransport of endosomesSynapse densityEndosomal sortingRemodeling of synapsesGTPase Rab4Vesicle transportAxonal transportRab4Motor proteinsDrosophila larvaeSynaptic atrophyMolecular mechanismsCentral nervous systemLarval stageActivity of insulinVesiclesSynaptic remodelingNeuropil regionsSynaptic plasticityGTPaseEndosomesTraffickingProteinNervous systemLarval
2025
Neurons exploit stochastic growth to rapidly and economically build dense dendritic arbors
Ouyang X, Sutradhar S, Trottier O, Shree S, Yu Q, Tu Y, Howard J. Neurons exploit stochastic growth to rapidly and economically build dense dendritic arbors. Nature Communications 2025, 16: 5903. PMID: 40593546, PMCID: PMC12217211, DOI: 10.1038/s41467-025-60800-7.Peer-Reviewed Original Research
2023
Dynamic microtubules slow down during their shrinkage phase
Luchniak A, Kuo Y, McGuinness C, Sutradhar S, Orbach R, Mahamdeh M, Howard J. Dynamic microtubules slow down during their shrinkage phase. Biophysical Journal 2023, 122: 616-623. PMID: 36659852, PMCID: PMC9989939, DOI: 10.1016/j.bpj.2023.01.020.Peer-Reviewed Original Research
2022
Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons
Shree S, Sutradhar S, Trottier O, Tu Y, Liang X, Howard J. Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons. Science Advances 2022, 8: eabn0080. PMID: 35767611, PMCID: PMC9242452, DOI: 10.1126/sciadv.abn0080.Peer-Reviewed Original Research
2021
Focal laser stimulation of fly nociceptors activates distinct axonal and dendritic Ca2+ signals
Basak R, Sutradhar S, Howard J. Focal laser stimulation of fly nociceptors activates distinct axonal and dendritic Ca2+ signals. Biophysical Journal 2021, 120: 3222-3233. PMID: 34175294, PMCID: PMC8390926, DOI: 10.1016/j.bpj.2021.06.001.Peer-Reviewed Original Research
2020
Ordering kinetics in a q-state random-bond clock model: Role of vortices and interfaces
Chatterjee S, Sutradhar S, Puri S, Paul R. Ordering kinetics in a q-state random-bond clock model: Role of vortices and interfaces. Physical Review E 2020, 101: 032128. PMID: 32290025, DOI: 10.1103/physreve.101.032128.Peer-Reviewed Original ResearchQ-state clock modelClock modelDisorder-dependent exponentNonequilibrium coarsening dynamicsMonte Carlo studyPower-law growthDynamical scalingInfinite temperatureQuenched disorderCoarsening dynamicsRole of vorticesCorrelation functionsStrength εCarlo studyTemperature T.Structure factorPhase transitionPure caseGrowth exponentInitial configurationDomain coarseningSimulation timescalesExponentDynamicsQuench
2019
A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation
Iyer P, Sutradhar S, Paul R, Bhattacharyya D. A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation. The European Physical Journal E 2019, 42: 154. PMID: 31834534, DOI: 10.1140/epje/i2019-11920-x.Peer-Reviewed Original Research
2016
Phase segregation in a binary fluid confined inside a nanopore
Basu S, Majumder S, Sutradhar S, Das S, Paul R. Phase segregation in a binary fluid confined inside a nanopore. EPL (Europhysics Letters) 2016, 116: 56003. DOI: 10.1209/0295-5075/116/56003.Peer-Reviewed Original ResearchEB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
Thomas G, Bandopadhyay K, Sutradhar S, Renjith M, Singh P, Gireesh K, Simon S, Badarudeen B, Gupta H, Banerjee M, Paul R, Mitra J, Manna T. EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nature Communications 2016, 7: 11665. PMID: 27225956, PMCID: PMC4894954, DOI: 10.1038/ncomms11665.Peer-Reviewed Original ResearchConceptsMicrotubule attachmentMicrotubule plus-end tracking protein EB1Plus-end tracking protein EB1Dynamic microtubulesMitotic chromosome alignmentMicrotubule latticeVertebrate cellsProtein complexesChromosome movementChromosome alignmentProtein EB1Biochemical experimentsEB1K-fibersDepletion resultsMicrotubulesVertebratesStructural studiesExtended structureSKA1EukaryotesKinetochoresImportant roleMitosisProtein
2015
Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability
Sutradhar S, Basu S, Paul R. Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability. Physical Review E 2015, 92: 042714. PMID: 26565279, DOI: 10.1103/physreve.92.042714.Peer-Reviewed Original ResearchConceptsMammalian cellsProper spindle formationBipolar mitotic spindleDifferent motor proteinsMost mammalian cellsStable bipolar spindleProper segregationDaughter cellsSpindle stabilityCell divisionMitotic spindleSpindle formationSpindle instabilityBipolar spindleDifferent physiological constraintsCell biologyMotor proteinsChromosomal configurationsInterpolar microtubulesPhysiological constraintsSpindle lengthChromosomal patternCellsMechanistic modelCrucial role
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Molecular Biophysics and Biochemistry
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