Raul J Guzman, MD
Donald Guthrie Professor of Vascular Surgery, Vice Chair, Faculty AffairsCards
About
Research
Publications
2025
High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice.
Jin Y, Cao F, Xie Y, Davis S, Dong G, Nigwekar S, Hansen J, Guzman R, Cai Y. High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice. Journal Of The American Society Of Nephrology 2025 PMID: 40960881, PMCID: PMC12448113, DOI: 10.1681/asn.0000000875.Peer-Reviewed Original ResearchChronic kidney diseaseChronic kidney disease miceCutaneous vascular calcificationArteriolar calcificationVascular calcificationP38 MAPK signalingMedial arterial calcificationPharmacological inhibition of p38 MAPK signalingArtery calcificationLow-protein dietPharmacological inhibitionMedial arteryInhibition of p38 MAPK signalingCKD mouse modelMolecular pathwaysMAPK signalingExperimental CKD modelsPharmacological inhibitor SB203580Kidney impairmentAlizarin red stainingNephrectomy miceSignaling in vivoVascular complicationsKidney dysfunctionTreatment strategiesSmoking Cessation Duration is associated with the risk of amputation after Revascularization for Chronic Limb-Threatening Ischemia
Carter W, Schwartz A, Sumpio B, Strosberg D, Tonnessen B, Cardella J, Guzman R, Ochoa Chaar C. Smoking Cessation Duration is associated with the risk of amputation after Revascularization for Chronic Limb-Threatening Ischemia. Journal Of Vascular Surgery 2025 PMID: 40912340, DOI: 10.1016/j.jvs.2025.08.037.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaCurrent smokersFormer smokersSmoking cessationMajor amputationLower extremity revascularizationCessation durationLimb-threatening ischemiaDuration of smoking cessationQuality InitiativeStandardized follow-up periodsRisk of amputationSmoking cessation durationVascular Quality InitiativeFormer smokingCurrent smokingPerioperative outcomesBlack racePeripheral vascular interventionsAmputationSmokingEnd-stage renal diseaseMonths of surgeryKaplan-Meier analysisFollow-up periodSmoking Cessation After Carotid Revascularization in the Vascular Quality Initiative
Schwartz A, Carter W, Zwibelman H, Lemmon G, Cardella J, Dardik A, Guzman R, Chaar C. Smoking Cessation After Carotid Revascularization in the Vascular Quality Initiative. Journal Of Vascular Surgery 2025, 82: e46-e47. DOI: 10.1016/j.jvs.2025.05.199.Peer-Reviewed Original ResearchTiming of outpatient stenting is associated with stent size in nonthrombotic iliac vein lesions
Schultz K, Rodriguez P, Ali S, Attaran R, Lozada J, Huber S, Tonnessen B, Aboian E, Guzman R, Chaar C. Timing of outpatient stenting is associated with stent size in nonthrombotic iliac vein lesions. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2025, 14: 102303. PMID: 40850563, PMCID: PMC12495162, DOI: 10.1016/j.jvsv.2025.102303.Peer-Reviewed Original ResearchNonthrombotic iliac vein lesionsIliac vein lesionsVein lesionsLate cohortStent sizeStent placementRetrospective studyRetrospective study of patientsMultivariate logistic regression analysisTime of stentingIliac vein stentingDay of surgeryStudy of patientsFirst-time treatmentEarly cohortMultivariate logistic regressionLogistic regression analysisIntravascular ultrasound examinationVein stentingVenous stentingStenting timeBaseline characteristicsUltrasound examinationVolume deficitsSmall stentsFrailty and Functional Decline after Elective Endovascular Abdominal Aortic Aneurysm Repair in Octogenarians
Li J, Slade M, Gill T, Bader J, Guzman R, Tonnessen B, Kuwayama D, Dardik A, Cardella J, Ochoa Chaar C. Frailty and Functional Decline after Elective Endovascular Abdominal Aortic Aneurysm Repair in Octogenarians. Journal Of Vascular Surgery 2025 PMID: 40835162, DOI: 10.1016/j.jvs.2025.08.011.Peer-Reviewed Original ResearchElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairModified Frailty IndexFollow-upRisk Analysis IndexRisk factorsAneurysm repairValidation cohortDevelopment cohortEastern Cooperative Oncology Group performance statusAsymptomatic infrarenal abdominal aortic aneurysmFunctional declineInfrarenal abdominal aortic aneurysmVascular Quality Initiative (VQI) databaseFrailty assessmentCongestive heart failureAbdominal aortic aneurysmLong-term mortality riskChronic obstructive pulmonary diseaseFrailty indexObstructive pulmonary diseasePreoperative factorsPreoperative comorbiditiesPilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease
Kim T, Brahmandam A, Alameddine D, Forman R, Hardik A, Fucito L, Mena-Hurtado C, Guzman R, Chaar C. Pilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease. Journal Of Vascular Surgery 2025, 82: a20. DOI: 10.1016/j.jvs.2025.05.139.Peer-Reviewed Original ResearchOutcomes of mechanical thrombectomy for acute limb ischemia at a tertiary referral center Presented at the Fifty-first Annual Meeting of the New England Society for Vascular Surgery, Portland, Maine, October 25-27, 2024.
Loh S, Nasir A, Strosberg D, Chaar C, Guzman R, Tonnessen B. Outcomes of mechanical thrombectomy for acute limb ischemia at a tertiary referral center Presented at the Fifty-first Annual Meeting of the New England Society for Vascular Surgery, Portland, Maine, October 25-27, 2024. European Journal Of Vascular And Endovascular Surgery 2025, 70: e15. DOI: 10.1016/j.ejvs.2025.06.015.Peer-Reviewed Original ResearchChallenging inferior vena cava filter removal complicated by strut penetration and prolonged dwell
Kostiuk V, Rodriguez P, Tonnessen B, Lozada J, Guzman R, Chaar C. Challenging inferior vena cava filter removal complicated by strut penetration and prolonged dwell. Journal Of Vascular Surgery Cases And Innovative Techniques 2025, 11: 101894. PMID: 40778295, PMCID: PMC12329293, DOI: 10.1016/j.jvscit.2025.101894.Peer-Reviewed Original ResearchInferior vena cavaInferior vena cava filter removalFilter removalAnticoagulant therapyStrut penetrationProximal right common iliac arteryPlacement of inferior vena cavaRight common iliac arteryFilter strut penetrationPulmonary embolism preventionInferior vena cava wallCommon iliac arteryL4 vertebral bodyEmbolism preventionFrequent complicationVena cavaFilter retrievalIliac arteryPatient's symptomsSurrounding organsVertebral bodyTemporary placementPatientsAnticoagulationTherapyPrediction model for safe contrast volume thresholds to prevent postcontrast acute kidney injury after endovascular abdominal aortic aneurysm repair
Bader J, Li Y, Lee C, Li J, Said S, Slade M, Huang Y, Kuwayama D, Guzman R, Ochoa Chaar C. Prediction model for safe contrast volume thresholds to prevent postcontrast acute kidney injury after endovascular abdominal aortic aneurysm repair. Journal Of Vascular Surgery 2025, 82: 833-844.e3. PMID: 40490161, DOI: 10.1016/j.jvs.2025.05.041.Peer-Reviewed Original ResearchElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairRisk of PC-AKIAbdominal aortic aneurysm repairMultivariate logistic regression analysisAortic aneurysm repairPC-AKIAcute kidney injuryLogistic regression analysisPerioperative mortalityAneurysm repairKidney injuryComplication of endovascular abdominal aortic aneurysm repairPatient characteristicsIncidence of preoperative comorbiditiesPost-contrast acute kidney injuryPostcontrast acute kidney injuryAssociated with development of chronic kidney diseaseAssociated with perioperative mortalityDevelopment of chronic kidney diseaseVascular Quality Initiative databasePreoperative patient characteristicsKaplan-Meier analysisProlonged hospital stayRenal artery stentingThe Incremental Risk of Major Amputation With Reinterventions in Patients With Peripheral Arterial Disease
Carter W, Alameddine D, Said S, Aboian E, Tonnessen B, Cardella J, Guzman R, Chaar C. The Incremental Risk of Major Amputation With Reinterventions in Patients With Peripheral Arterial Disease. Journal Of Vascular Surgery 2025, 81: e186-e187. DOI: 10.1016/j.jvs.2025.03.332.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Dr. Raul Guzman is chief of the division of vascular surgery and endovascular therapy at Yale New Haven Hospital. He is also surgeon-in-chief, vascular surgery at the Heart and Vascular Center for the Yale New Haven Health System.
Dr. Guzman joins Yale Medicine from Beth Israel Deaconess Medical Center and Harvard Medical School. Prior to moving to Boston, he spent the early portion of his career at Vanderbilt Medical Center in Nashville, Tennessee, where he served for several years as chief of vascular surgery at the Nashville VA Hospital.
He received his medical degree from Johns Hopkins University in Baltimore, MD. After completing his residency in general surgery, he completed research training in the cardiology branch of the National Heart, Lung, and Blood Institute at the National Institutes of Health (NIH) and subsequently completed a fellowship in vascular surgery at Stanford University Hospital.
He recently completed his term as a permanent member of the Bioengineering, Technology, and Surgical Sciences Study Section of the NIH. His clinical interests relate to patients who have diabetic vascular disease, peripheral artery disease, and preventing amputation. His research focuses on the role of arterial calcification in lower extremity ischemia.
Clinical Specialties
Vascular & Endovascular Surgery
Fact Sheets
Vascular Surgery
Learn More on Yale MedicinePeripheral Artery Disease (PAD)
Learn More on Yale MedicineAortic Aneurysm
Learn More on Yale MedicinePeripheral Vascular Disease (PVD)
Learn More on Yale Medicine
Board Certifications
Vascular Surgery
- Certification Organization
- AB of Surgery
- Original Certification Date
- 1998
Yale Medicine News
News
News
- December 18, 2025
Yale Surgery Team Marks Milestone with 100th Complex Endovascular Aortic Repair
- December 12, 2024
Yale Vascular Surgery Launches Same-Day Dialysis Access Program
- December 12, 2024
Dr. Raul Guzman Receives the 2024 Dr. Walter E. Longo MD Award
- June 03, 2024
Vascular Innovates Sedation Model to Alleviate OR Capacity
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