Brian West, MD
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Appointments
Pathology
Primary
Contact Info
About
Titles
Professor Emeritus of and Senior Research Scientist in Pathology
Appointments
Pathology
EmeritusPrimary
Other Departments & Organizations
- Pancreatic Diseases Program
- Pathology
- Pathology and Molecular Medicine
- Pediatric and Perinatal Pathology
- Yale Ventures
Education & Training
- Fellow
- Yale University School of Medicine (1989)
- Resident
- Yale-New Haven Hospital (1988)
- Resident
- Federated and St. James Hospital System (1986)
- MD
- University of Dublin (1979)
- MA
- University of Dublin (1969)
Board Certifications
Anatomic Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 1989
Research
Overview
Medical Subject Headings (MeSH)
Gastrointestinal Neoplasms; Pathology, Surgical
Research at a Glance
Yale Co-Authors
Frequent collaborators of Brian West's published research.
Publications Timeline
A big-picture view of Brian West's research output by year.
Guadalupe Garcia-Tsao, MD, FRCP
Harvey Risch, MD, PhD
10Publications
953Citations
Publications
2007
Alcohol dehydrogenase 3 and risk of esophageal and gastric adenocarcinomas
Terry MB, Gammon MD, Zhang FF, Vaughan TL, Chow WH, Risch HA, Schoenberg JB, Mayne ST, Stanford JL, West AB, Rotterdam H, Blot WJ, Fraumeni JF, Santella RM. Alcohol dehydrogenase 3 and risk of esophageal and gastric adenocarcinomas. Cancer Causes & Control 2007, 18: 1039-1046. PMID: 17665311, DOI: 10.1007/s10552-007-9046-0.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdenocarcinomaAdultAgedAlcohol DehydrogenaseAlcohol DrinkingAllelesCase-Control StudiesChi-Square DistributionConfidence IntervalsEsophageal NeoplasmsFemaleGene FrequencyGenotypeHomozygoteHumansInterviews as TopicLogistic ModelsMaleMiddle AgedOdds RatioPolymorphism, GeneticRisk FactorsStomach NeoplasmsUnited StatesConceptsRisk of esophagealEsophageal adenocarcinomaHigh riskGastric Cancer StudyGastric cardia adenocarcinomaGastric adenocarcinomaCarcinoma riskConclusionThese dataCancer riskCardia adenocarcinomaTumor typesAdenocarcinomaAlcohol dehydrogenase 3Common polymorphismsEsophagealRisk estimatesCancer studiesRiskAlcohol dehydrogenase 3 geneDrinkersDehydrogenase 3PolymorphismNondrinkersMethodsWeGenotypes
2005
Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis
Combes B, Emerson SS, Flye NL, Munoz SJ, Luketic VA, Mayo MJ, McCashland TM, Zetterman RK, Peters MG, Di Bisceglie AM, Benner KG, Kowdley KV, Carithers RL, Rosoff L, Garcia‐Tsao G, Boyer JL, Boyer TD, Martinez EJ, Bass NM, Lake JR, Barnes DS, Bonacini M, Lindsay KL, Mills AS, Markin RS, Rubin R, West AB, Wheeler DE, Contos MJ, Hofmann AF. Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis. Hepatology 2005, 42: 1184-1193. PMID: 16250039, DOI: 10.1002/hep.20897.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPrimary biliary cirrhosisUrsodeoxycholic acidVariceal bleedingBiliary cirrhosisTreatment failureSerum bilirubinHistological stagingCourse of PBCM2 body surface areaData Safety Monitoring BoardAMA-positive patientsReasons of futilityFailure of treatmentDevelopment of ascitesBody surface areaSafety monitoring boardEffect of methotrexateLiver transplantationPositive patientsMulticenter trialMedian periodMedian timeHistological progressionMonitoring boardDrug toxicity
2004
Characterization of “Candidatus Piscichlamydia salmonis” (Order Chlamydiales), a Chlamydia-Like Bacterium Associated With Epitheliocystis in Farmed Atlantic Salmon (Salmo salar)
Draghi A, Popov VL, Kahl MM, Stanton JB, Brown CC, Tsongalis GJ, West AB, Frasca S. Characterization of “Candidatus Piscichlamydia salmonis” (Order Chlamydiales), a Chlamydia-Like Bacterium Associated With Epitheliocystis in Farmed Atlantic Salmon (Salmo salar). Journal Of Clinical Microbiology 2004, 42: 5286-5297. PMID: 15528727, PMCID: PMC525185, DOI: 10.1128/jcm.42.11.5286-5297.2004.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRRNA gene sequencesCandidatus Piscichlamydia salmonisRibosomal DNAPiscichlamydia salmonisGene sequencesAtlantic salmonReticulate bodiesDevelopmental stagesMolecular phylogenetic relationshipsMolecular phylogenetic analysisEpitheliocystis inclusionsPhylogenetic relationshipsPhylogenetic analysisOrder ChlamydialesRDNA ampliconsBacterium AssociatedNucleotide identityGenomic DNABinary fissionFarmed Atlantic SalmonEpitheliocystisTail cellsImmunoelectron microscopyGill samplesSitu hybridizationNomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers
Roskams TA, Theise ND, Balabaud C, Bhagat G, Bhathal PS, Bioulac‐Sage P, Brunt EM, Crawford JM, Crosby HA, Desmet V, Finegold MJ, Geller SA, Gouw AS, Hytiroglou P, Knisely AS, Kojiro M, Lefkowitch JH, Nakanuma Y, Olynyk JK, Park YN, Portmann B, Saxena R, Scheuer PJ, Strain AJ, Thung SN, Wanless IR, West AB. Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers. Hepatology 2004, 39: 1739-1745. PMID: 15185318, DOI: 10.1002/hep.20130.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords”Fractured Colon”
Sherman A, Ackert JJ, Rajapaksa R, West AB, Oweity T. ”Fractured Colon”. Journal Of Clinical Gastroenterology 2004, 38: 341-345. PMID: 15087693, DOI: 10.1097/00004836-200404000-00008.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsCollagenous colitisTissue specimensChronic nonbloody diarrheaLinear mucosal tearsFree intraperitoneal airPatient tissue specimensFibrotic submucosaNonbloody diarrheaAcute peritonitisColonic perforationClinical courseIntraperitoneal airMucosal tearsPlain radiographsResection specimenDiagnostic colonoscopyLinear ulcerSubmucosal fibrosisColonic mucosaCollagen depositionSurface epitheliumAir dissectionAir insufflationColitisVariable severity
2003
Stellate-Cell Lipidosis in Liver Biopsy Specimens
Levine PH, Delgado Y, Theise ND, West AB. Stellate-Cell Lipidosis in Liver Biopsy Specimens. American Journal Of Clinical Pathology 2003, 119: 254-258. PMID: 12579996, DOI: 10.1309/6dkc03c4gaaen2dk.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLiver biopsy specimensHypervitaminosis ABiopsy specimensAbnormal liver enzyme levelsOral vitamin ALiver enzyme levelsLipid-laden cellsCrescent-shaped nucleusMethotrexate useHepatitis CLiver biopsyLiver injuryMedication useTopical tretinoinSpace of DisseInconspicuous nucleoliPreventable formAlcohol abuseDiagnostic criteriaVitamin ALipidosisSynthetic retinoidsPatient detailsBiopsyPatients
1997
Mucosal Inflammation in Pediatric Diversion Colitis: A Quantitative Analysis
Grant N, Van Kruiningen H, Haque S, West A. Mucosal Inflammation in Pediatric Diversion Colitis: A Quantitative Analysis. Journal Of Pediatric Gastroenterology And Nutrition 1997, 25: 273-280. DOI: 10.1002/j.1536-4801.1997.tb01748.x.Peer-Reviewed Original ResearchConceptsDiversion colitisT cellsPlasma cellsPediatric controlsLymphoid folliclesLymphoid tissueMucosa-associated lymphoid tissuePersistent antigenic stimulationIgA-containing plasma cellsMucosa of childrenInflammatory cell populationsHirschsprung's disease patientsSegment of colonFollicular compartmentMucosal inflammationT lymphocytesAntigenic stimulationB cellsB lymphocytesParaffin blocksColorectal tissuesLamina propriaColitisMuscularis mucosaeAdult controls
1992
Familial Adenomatous Polyposis Following Liver Transplantation for a Virilizing Hepatoblastoma
Shneider B, Haque S, van Hoff J, Touloukian R, West A. Familial Adenomatous Polyposis Following Liver Transplantation for a Virilizing Hepatoblastoma. Journal Of Pediatric Gastroenterology And Nutrition 1992, 15: 198-201. DOI: 10.1002/j.1536-4801.1992.tb10632.x.Peer-Reviewed Original Research
1989
Assessing the injured ankle without X‐rays
West A. Assessing the injured ankle without X‐rays. International Journal Of Clinical Practice 1989, 43: 360-362. PMID: 2629945, DOI: 10.1111/j.1742-1241.1989.tb08772.x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and Concepts
Others
- Lamps LW, Molina CP, West AB, Haggitt RC, Scott MA. The histopathologic spectrum of gastrointestinal and hepatic histoplasmosis. Am J Clin Pathol 2000113:64-72.Peer-Reviewed Original Research
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