Richard Mattson, MD
Professor Emeritus of NeurologyCards
About
Titles
Professor Emeritus of Neurology
Adjunct Professor of Nursing, Yale Nursing School
Biography
Dr Mattson was born and raised in Connecticut, attended and received a BS degree from Yale University followed by his M.D. from Boston University. He did his neurology residency and a clinical neurophysiology fellowship at the Mayo Clinic in Rochester, MN. While there he did research on interruption of the spread of epileptic seizures in an animal models and received an M.S. degree.
Following his formal training Dr. Mattson spent five more years with the USAF in San Antonio, TX. During that time he and his colleagues did the original studies on the effect of sleep deprivation on the occurrence of epileptic seizures and as an activating technique in EEG.
In 1967 Dr. Gilbert Glaser, M.D., Professor and Chair of Neurology, recruited him to the faculty at the Yale School of Medicine primarily to develop one of the world’s first Epilepsy Intensive Monitoring Units and they founded what is now known as the Yale Comprehensive Epilepsy Center.
His special area of interest increasingly turned toward antiepileptic drug therapy. He directed the two largest multi-center (VA Coop) studies that defined the effectiveness and adverse effects of the standard antiepileptic drugs (AEDs). He continues to be active in development and evaluation the new AEDs. For almost two decades Dr. Mattson directed the Yale/NIH Program Project that studied both clinical and basic aspects of epilepsy.
He has authored or co-authored more than 250 original papers, reviews and chapters most in the field of epilepsy and is co-editor of a number of books including the standard reference, Antiepileptic Drugs. He has been invited to speak throughout the world on the topic of epilepsy.
In addition Dr Mattson has been active in education and was former Vice Chairman for Academic Affairs in Neurology as well as Director of the Yale Neurology Residency Program and the founder and first Director of Clinical Neuroscience Education and Clerkship at Yale School of Medicine. He also for 20 years has chaired the J. Kiffin Penry Epilepy Minifellowships, the largest postgraduate Educational Epilepsy Program in the USA.
Dr Mattson has been the President of the American Epilepsy Society. He has been recognized with a number of prizes and awards including The William Lennox Award of the American Epilepsy Society, the Novartis/ILAE Epileptology Prize, The Hans Berger Award, The Clinical Investigator Award of American Epilepsy Society/Milken Family Foundation and the Hans Berger Distinguished Scholar Award He is recognized by Who’ Who in the World and Best Doctors in America.
Dr. Mattson continues to be active in teaching and clinical care of adults and children with epilepsy.
Appointments
Other Departments & Organizations
Education & Training
- MS
- Mayo Medical School (Univ. of Minnesota), neurology (neurophysiology) (1962)
- Fellow
- Mayo Clinic (1962)
- Resident
- Mayo Clinic (1962)
- MD
- Boston University (1957)
- BS
- Yale College, Zoology (1953)
Board Certifications
Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 1964
Research
Publications
1985
Interhemispheric commissurotomy for congenital hemiplegics with intractable epilepsy.
Goodman R, Williamson P, Reeves A, Spencer S, Spencer D, Mattson R, Roberts D. Interhemispheric commissurotomy for congenital hemiplegics with intractable epilepsy. Neurology 1985, 35: 1351-4. PMID: 4022384, DOI: 10.1212/wnl.35.9.1351.Peer-Reviewed Original Research
1984
Intracerebral masses in patients with intractable partial epilepsy.
Spencer D, Spencer S, Mattson R, Williamson P. Intracerebral masses in patients with intractable partial epilepsy. Neurology 1984, 34: 432-6. PMID: 6422323, DOI: 10.1212/wnl.34.4.432.Peer-Reviewed Original ResearchConceptsPartial seizuresSubtotal lobectomyUncontrolled partial seizuresGood seizure controlIntractable partial epilepsySimple partial seizuresIntracranial mass lesionsForm of treatmentSeizure controlMass resectionNeurologic examinationPreoperative evaluationSurgical treatmentIntracerebral massPartial epilepsyRadiologic studiesMass lesionStructural lesionsPatientsSeizuresLesionsLobectomyNeoplasmsTreatmentResection
1983
Sexual automatisms in complex partial seizures.
Spencer S, Spencer D, Williamson P, Mattson R. Sexual automatisms in complex partial seizures. Neurology 1983, 33: 527-33. PMID: 6682492, DOI: 10.1212/wnl.33.5.527.Peer-Reviewed Original ResearchConceptsComplex partial seizuresSexual automatismsPartial seizuresRefractory complex partial seizuresTemporal lobe diseaseFrontal lobe pathologySeizure frequencyFrontal lobectomySeizure focusSeizure originCalcified lesionsPatientsPelvic thrustingFrontal lobeSeizuresDepth EEGMasturbatory activityAutomatismsLobectomyLesionsDiseasePathology
1976
Eterobarb therapy in epilepsy.
MATTSON R, WILLIAMSON P, HANAHAN E. Eterobarb therapy in epilepsy. Neurology 1976, 26: 1014-7. PMID: 824567, DOI: 10.1212/wnl.26.11.1014.Peer-Reviewed Original ResearchConceptsDouble-blind crossover studySerum barbiturate levelsType of epilepsySuperior therapeutic effectSerious systemic toxicityAlternative anticonvulsantAnticonvulsant effectsSeizure frequencyStatus epilepticusCrossover studyTherapeutic effectSide effectsBarbiturate levelsSystemic toxicityPatientsEterobarbPhenobarbitalHigh dosageSignificant differencesEpilepsyTherapyTrialsToxicityEpilepticusAnticonvulsants
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Contacts
Administrative Support
Locations
Yale School of Medicine
Academic Office
Lippard Lab for Clinical Investigation
15 York Street, Ste PO Box 208018
New Haven, CT 06510
Fax
203.737.2799