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Erol Fikrig, MD

Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis; Affiliated Faculty, Yale Institute for Global Health; Section Chief, Infectious Diseases, Internal Medicine

Contact Information

Erol Fikrig, MD

Office Location

Research Summary

My laboratory investigates vector-borne diseases, including illnesses transmitted by ticks and mosquitoes. Studies are directed toward understanding Lyme disease, human granulocytic ehrlichiosis, flaviviruses and malaria. Efforts on Lyme disease include exploring immunity to Borrelia burgdorferi, and the immunobiology of Lyme arthritis. We are investigating the molecular strategies that Anaplasma phagocytophilum uses to survive in polymorphonuclear leukocytes or ticks. Finally, we are also developing molecular approaches to prevent ticks or mosquitoes from feeding on a mammalian host, thereby interfering with pathogen transmission.

Specialized Terms: Vector-borne diseases; Ticks; Mosquitoes; Lyme disease; Human granulocytic ehrilichiosis; West Nile virus; malaria


Research Interests

Bacteria; Epidemiology; Lyme Disease; Parasitology; Public Health; Ticks; Viruses; West Nile virus; Global Health; Ehrlichiosis; Malaria Vaccines; Borrelia burgdorferi; Infectious Disease Medicine

Public Health Interests

Infectious Diseases; Mosquito-borne Diseases; Tick-borne Diseases

Selected Publications

Clinical Trials

ConditionsStudy Title
Immune System; Men's Health; Women's HealthEffects of circadian regulation and sleep on immune responses
HIV/AIDSMechanisms of HIV latency