2023
A Longitudinal Study of Respiratory Mechanics in Pregnant Women with Obesity and Overweight
Bourjeily G, Sanapo L, Messerlian G, Bublitz M, Hott B, Guillen M, Aldana A, Avalos A, Sequeira T, Felber C, Brosnan C, Zarif T, McCool F. A Longitudinal Study of Respiratory Mechanics in Pregnant Women with Obesity and Overweight. Lung 2023, 201: 371-379. PMID: 37421433, DOI: 10.1007/s00408-023-00633-7.Peer-Reviewed Original ResearchMeSH KeywordsAirway ResistanceFemaleHumansLongitudinal StudiesLungObesityOverweightPregnancyProgesteroneRespiratory MechanicsSpirometryConceptsLate pregnancyAirway resistanceSex hormonesPregnancy progressionSupine positionProgesterone levelsMedian body mass indexMeasurement of airway resistanceRespiratory system reactanceBody mass indexCentral airway resistanceEarly pregnancyMethodsA longitudinal studyMass indexPregnancyLung mechanicsPregnant womenLongitudinal studySeated positionRespiratory mechanicsStudy of respiratory mechanicsHormoneSystem reactanceProgesteroneAirway
2019
Physiologic Basis of Symptoms in Pleural Disease
DeBiasi EM, Feller-Kopman D. Physiologic Basis of Symptoms in Pleural Disease. Seminars In Respiratory And Critical Care Medicine 2019, 40: 305-313. PMID: 31525806, DOI: 10.1055/s-0039-1693648.BooksConceptsPleural effusionPleural pressureEffect of thoracentesisIdentification of patientsLength-tension relationshipUnexpandable lungMost patientsRespiratory musclesPerfusion matchingPleural diseaseLung volumeRespiratory mechanicsPhysiologic basisThoracentesisPathophysiological effectsPhysiologic parametersRespiratory systemPatientsEffusionImproved ventilationRoutine monitoringHeterogeneous populationOxygenationPalliationComplications
2017
Non-Rigid Event-by-Event Continuous Respiratory Motion Compensated List-Mode Reconstruction for PET
Chan C, Onofrey J, Jian Y, Germino M, Papademetris X, Carson RE, Liu C. Non-Rigid Event-by-Event Continuous Respiratory Motion Compensated List-Mode Reconstruction for PET. IEEE Transactions On Medical Imaging 2017, 37: 504-515. PMID: 29028189, PMCID: PMC7304524, DOI: 10.1109/tmi.2017.2761756.Peer-Reviewed Original ResearchConceptsMotion-compensated image reconstructionMotion fieldImage reconstructionReconstruction algorithmRespiratory motionNon-rigid motionNon-rigid motion correctionSignificant image blurringSystem matrixMotion correctionSystem matrix calculationMotionImage blurringSuperior image qualityTracer concentrationRigid motionReference locationMatrix calculationList-mode reconstruction algorithmMotion correlationDynamics studyImage quality
2016
Event-by-Event Continuous Respiratory Motion Correction for Dynamic PET Imaging
Yu Y, Chan C, Ma T, Liu Y, Gallezot JD, Naganawa M, Kelada OJ, Germino M, Sinusas AJ, Carson RE, Liu C. Event-by-Event Continuous Respiratory Motion Correction for Dynamic PET Imaging. Journal Of Nuclear Medicine 2016, 57: 1084-1090. PMID: 26912437, DOI: 10.2967/jnumed.115.167676.Peer-Reviewed Original Research
2015
Reproducibility of fractional ventilation derived by Fourier decomposition after adjusting for tidal volume with and without an MRI compatible spirometer
Voskrebenzev A, Gutberlet M, Becker L, Wacker F, Vogel‐Claussen J. Reproducibility of fractional ventilation derived by Fourier decomposition after adjusting for tidal volume with and without an MRI compatible spirometer. Magnetic Resonance In Medicine 2015, 76: 1542-1550. PMID: 26745750, DOI: 10.1002/mrm.26047.Peer-Reviewed Original ResearchConceptsFractional ventilationTidal volumeTidal volume variationsInfluence of tidal volumeLung volume changesTidal volume differenceIntraclass correlation coefficientFree breathingFourier decompositionSpoiled gradient-echo imagesTesla scannerGradient-echo imagesSagittal slicesArea changeLungVolunteer cohortReproducibility analysisVolume differencesMRIEcho imagesRepeated measuresSpirometerVolunteersVentilationCoefficient of variationVentilator gas delivery wave form substantially impacts plateau pressure and peak-to-plateau pressure gradient determination
Maung AA, Johnson DC, Luckianow GM, Kaplan LJ. Ventilator gas delivery wave form substantially impacts plateau pressure and peak-to-plateau pressure gradient determination. Journal Of Trauma And Acute Care Surgery 2015, 78: 976-979. PMID: 25909418, DOI: 10.1097/ta.0000000000000615.Peer-Reviewed Original ResearchConceptsAdult surgical intensive care unitAdult intensive care unit patientsSurgical intensive care unitIntensive care unit patientsPeak airway pressureCare unit patientsIntensive care unitAirway pressureUnit patientsIll patientsCare unitNeuromuscular blockadeVentilator parametersUnwarranted therapyPplatPatientsLevel IIINormal valuesDiagnostic studiesVentilation parametersPressure measurementsPlateau pressureFentanylPropofolMidazolam
2014
New Generation Neonatal High Frequency Ventilators: Effect of Oscillatory Frequency and Working Principles on Performance
Grazioli S, Karam O, Rimensberger PC. New Generation Neonatal High Frequency Ventilators: Effect of Oscillatory Frequency and Working Principles on Performance. Respiratory Care 2014, 60: 363-370. PMID: 25406342, DOI: 10.4187/respcare.03048.Peer-Reviewed Original ResearchConceptsVolume-targeted modesInfant's conditionNeonatal ventilatorsPre-term infantsRespiratory system conditionsHigh-frequency ventilationExpiratory tidal volumeLung mechanical propertiesTerm infantsPreclinical dataVentilator settingsFrequency ventilationClinical conditionsLung characteristicsTidal volumeClinical relevanceInfant settingsVentilatorFurther studies
2013
Waveform analysis during mechanical ventilation
Maung AA, Kaplan LJ. Waveform analysis during mechanical ventilation. Current Problems In Surgery 2013, 50: 438-446. PMID: 24156841, DOI: 10.1067/j.cpsurg.2013.08.007.Peer-Reviewed Original Research
2012
Mechanical Ventilation After Injury
Maung AA, Kaplan LJ. Mechanical Ventilation After Injury. Journal Of Intensive Care Medicine 2012, 29: 128-137. PMID: 22956744, DOI: 10.1177/0885066612457339.Peer-Reviewed Original ResearchMeSH KeywordsBlast InjuriesBrain InjuriesBronchial FistulaHumansPleural DiseasesRespiratory MechanicsRespiratory Tract FistulaVentilator WeaningWounds and InjuriesConceptsMechanical ventilationPrimary respiratory failureTraumatic brain injuryMultiple organ systemsImpact of injuryConcomitant tissue injuryRespiratory failureCritical illnessVentilator strategiesBronchopleural fistulaVentilator managementBrain injuryPhysiologic changesTissue injuryBlast injuryInjuryThermal injuryOrgan systemsPatientsMajor causeVentilationSpecial considerationFistulaIllnessUsing Time-Frequency Analysis of the Photoplethysmographic Waveform to Detect the Withdrawal of 900 mL of Blood
Scully CG, Selvaraj N, Romberg FW, Wardhan R, Ryan J, Florian JP, Silverman DG, Shelley KH, Chon KH. Using Time-Frequency Analysis of the Photoplethysmographic Waveform to Detect the Withdrawal of 900 mL of Blood. Anesthesia & Analgesia 2012, 115: 74-81. PMID: 22543068, DOI: 10.1213/ane.0b013e318256486c.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureBlood Pressure DeterminationBlood Transfusion, AutologousBlood VolumeBlood Volume DeterminationCluster AnalysisConnecticutElectrocardiographyHeart RateHumansHypovolemiaInfrared RaysMalePhotoplethysmographyPredictive Value of TestsRespiratory MechanicsSensitivity and SpecificitySignal Processing, Computer-AssistedTime FactorsConceptsML of bloodArterial blood pressureBlood lossBlood pressureHeart rateHeart rate frequencyBlood withdrawalML blood lossMean percent decreaseBlood volume lossHeart rate componentSignificant changesPhotoplethysmographic waveformSpontaneous breathingTrauma settingCuff measurementsPPG waveformBlood reinfusionHealthy volunteersStandard electrocardiogramBloodEarly detectionEar PPG signalsBaselineConfidence intervalsRespiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform
Alian AA, Shelley KH. Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform. Sensors 2012, 12: 2236-2254. PMID: 22438762, PMCID: PMC3304164, DOI: 10.3390/s120202236.Peer-Reviewed Original Research
2011
Consensus definitions to promote an evidence-based approach to management of the pleural space. A collaborative proposal by ESTS, AATS, STS, and GTSC
Brunelli A, Beretta E, Cassivi SD, Cerfolio RJ, Detterbeck F, Kiefer T, Miserocchi G, Shrager J, Singhal S, Van Raemdonck D, Varela G. Consensus definitions to promote an evidence-based approach to management of the pleural space. A collaborative proposal by ESTS, AATS, STS, and GTSC. European Journal Of Cardio-Thoracic Surgery 2011, 40: 291-297. PMID: 21757129, DOI: 10.1016/j.ejcts.2011.05.020.Peer-Reviewed Original ResearchRespiratory motion correction for quantitative PET/CT using all detected events with internal—external motion correlation
Liu C, Alessio AM, Kinahan PE. Respiratory motion correction for quantitative PET/CT using all detected events with internal—external motion correlation. Medical Physics 2011, 38: 2715-2723. PMID: 21776808, PMCID: PMC3107832, DOI: 10.1118/1.3582692.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtifactsHumansImage EnhancementImage Interpretation, Computer-AssistedMotionMovementNeoplasmsPositron-Emission TomographyReproducibility of ResultsRespiratory MechanicsRespiratory-Gated Imaging TechniquesSensitivity and SpecificityStatistics as TopicSubtraction TechniqueTomography, X-Ray ComputedConceptsPET listmode dataInternal motionsExternal motion signalExternal respiratory signalListmode dataTumor motion informationRespiratory-gated PET imagesCT attenuation mapsMotion correlationPhantom experimentsRespiratory motion signalMotion degradationMotion correctionTumor motionSUVmax increaseAttenuation mapResidual motionAttenuation correctionSinogramRespiratory motion correctionQuantitative PET/CTMotionReference frameRespiratory motionPET images
2010
Ventilatory patterning in a mouse model of stroke
Koo BB, Strohl KP, Gillombardo CB, Jacono FJ. Ventilatory patterning in a mouse model of stroke. Respiratory Physiology & Neurobiology 2010, 172: 129-135. PMID: 20472101, PMCID: PMC3698953, DOI: 10.1016/j.resp.2010.05.008.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationRespiratory rateCerebral infarctionMale A/J miceWhole-body plethysmographyAbsence of strokeLower respiratory rateBody plethysmographySham procedureSham animalsJ miceMinute ventilationVentilatory patternTidal volumeMouse modelBreathing patternAnimal modelsVentilatory dataStrokeBreathing instabilityInfarctionVentilationCausal pathwaysBreath volumeBreathingPharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs
Heerdt PM, Malhotra JK, Pan BY, Sunaga H, Savarese JJ. Pharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs. Anesthesiology 2010, 112: 910-916. PMID: 20234311, DOI: 10.1097/aln.0b013e3181d31f71.Peer-Reviewed Original ResearchConceptsX ED95Neuromuscular blocking drugsCardiopulmonary side effectsVascular resistanceArterial pressureBlocking drugsCardiac outputHistamine releaseSide effectsMean pulmonary artery pressurePulmonary artery pressurePulmonary vascular resistanceSystemic vascular resistanceMean arterial pressurePulmonary arterial pressureArtery pressureHemodynamic effectsPulmonary complianceVentricular contractilityInspiratory pressureNeuromuscular blockadeVentricular pressureED95Large dosesCW002
2009
Peripheral venous pressure waveform
Wardhan R, Shelley K. Peripheral venous pressure waveform. Current Opinion In Anaesthesiology 2009, 22: 814. PMID: 19844178, DOI: 10.1097/aco.0b013e328332a343.Peer-Reviewed Original ResearchConceptsPeripheral venous pressure waveformsPeripheral intravenous cathetersPeripheral venous pressurePeripheral venous systemCarotid artery puncturePressure waveformVenous waveformVenous pressureArtery punctureIntraoperative monitoringIntravenous cathetersVenous systemRespiratory variationCardiovascular homeostasisInvasive monitoringArterial waveformProcedure timeVenous componentPhysiologic challengesFurther studiesCirculatory systemInexpensive monitoring deviceNumerous studiesCritical rolePneumothoraxPortable Spirometry During Acute Exacerbations of Asthma in Children
Langhan ML, Spiro DM. Portable Spirometry During Acute Exacerbations of Asthma in Children. Journal Of Asthma 2009, 46: 122-125. PMID: 19253115, DOI: 10.1080/02770900802460522.Peer-Reviewed Original ResearchConceptsAcute exacerbationPediatric emergency departmentPortable spirometryEmergency departmentClinical signsAirway obstructionExpiratory volumeClinical scoresExpiratory flowUrban pediatric emergency departmentCorrelation of spirometryHistory of asthmaAssessment of asthmaPeak expiratory flowPercent of subjectsYears of ageBronchodilator treatmentMedian ageVital capacitySpirometryExacerbationOxygen saturationAsthmaRespiratory rateVital signs
2008
2D free‐breathing dual navigator‐gated cardiac function validated against the 2D breath‐hold acquisition
Peters DC, Nezafat R, Eggers H, Stehning C, Manning WJ. 2D free‐breathing dual navigator‐gated cardiac function validated against the 2D breath‐hold acquisition. Journal Of Magnetic Resonance Imaging 2008, 28: 773-777. PMID: 18777547, PMCID: PMC2562245, DOI: 10.1002/jmri.21417.Peer-Reviewed Original Research
2007
Hypothalamic-Pituitary-Adrenal Axis Activity in Obese Men with and without Sleep Apnea: Effects of Continuous Positive Airway Pressure Therapy
Vgontzas A, Pejovic S, Zoumakis E, Lin H, Bentley C, Bixler E, Sarrigiannidis A, Basta M, Chrousos G. Hypothalamic-Pituitary-Adrenal Axis Activity in Obese Men with and without Sleep Apnea: Effects of Continuous Positive Airway Pressure Therapy. The Journal Of Clinical Endocrinology & Metabolism 2007, 92: 4199-4207. PMID: 17785363, DOI: 10.1210/jc.2007-0774.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureSleep apneaHypothalamic-pituitary-adrenal axis activityNonobese controlsApneic patientsObese menCRH administrationCortisol secretionLow cortisol secretionImpact of continuous positive airway pressureContinuous positive airway pressure therapyContinuous positive airway pressure useMonths of CPAP usePositive airway pressure therapyAxis activityOvine CRH administrationAirway pressure therapyPositive airway pressureEffects of continuous positive airway pressure therapyHypothalamic-pituitary-adrenal axisSleep apneic patientsCortisol levelsCPAP useACTH responseAirway pressure
2006
Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats
Radulovacki M, Stoiljkovic M, Saponjic J, Carley D. Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats. Respiratory Physiology & Neurobiology 2006, 156: 40-46. PMID: 16934539, DOI: 10.1016/j.resp.2006.07.005.Peer-Reviewed Original ResearchConceptsNon-NMDA receptorsIntertrigeminal regionNMDA receptorsReflex apneaNonspecific glutamate receptor antagonist kynurenic acidGlutamate receptor antagonist kynurenic acidSpecific NMDA receptor antagonistRespiratory responsesAntagonist kynurenic acidVentral respiratory groupMicroinjection of glutamateNMDA receptor antagonistSleep-related apneaLong-term potentiationFunctional NMDA receptorsImmediate apneaVagal reflexGlutamate injectionRespiratory groupRespiratory disturbancesKynurenic acidReceptor antagonistSelective blockadeApneaLateral pons
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