2024
An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms
Fesharaki-Zadeh A, Datta D. An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms. Frontiers In Cellular Neuroscience 2024, 18: 1371213. PMID: 38682091, PMCID: PMC11045909, DOI: 10.3389/fncel.2024.1371213.Peer-Reviewed Original ResearchClosed-Head Impact Model of Engineered Rotational AccelerationModel of traumatic brain injuryPreclinical modelsPreclinical models of traumatic brain injuryAnimal modelsTraumatic brain injuryControlled cortical impact injuryRodent preclinical modelsDisease modifying effectFluid percussion injuryCortical impact injuryBlast injuryAnimal models of traumatic brain injuryBrain injuryMotor vehicle accidentsTherapeutic regimenPathophysiological mechanismsEtiology of traumatic brain injuryPharmacological agentsSports related injuriesInjury modelCalcium dysregulationPrevalence of traumatic brain injuryClinical treatmentClinical setting
2022
The Beirut ammonium nitrate blast: A multicenter study to assess injury characteristics and outcomes
Al-Hajj S, Farran SH, Zgheib H, Tfaily MA, Halaoui A, Wehbe S, Karam S, Fadlallah Y, Fahd F, Toufaili L, Arjinian S, Al-Zaghrini E, Al Hariri M, El Hussein M, Souaiby N, Mowafi H, Mufarrij AJ. The Beirut ammonium nitrate blast: A multicenter study to assess injury characteristics and outcomes. Journal Of Trauma And Acute Care Surgery 2022, 94: 328-335. PMID: 35999664, DOI: 10.1097/ta.0000000000003745.Peer-Reviewed Original ResearchConceptsInjury characteristicsInjury predictorsBlast injuryMulticenter cross-sectional studyMajor acute care hospitalsHospital chart reviewInjury Severity ScoreIntensive care unitAcute care hospitalsCross-sectional studyHead/faceSecondary blast injuriesPrimary blast injuryChart reviewNeurologic disabilityEye injuriesTrauma patientsCare unitMultiple injuriesBlast lungMulticenter studyMean ageFrequent siteMost injuriesSeverity score
2012
Mechanical Ventilation After Injury
Maung AA, Kaplan LJ. Mechanical Ventilation After Injury. Journal Of Intensive Care Medicine 2012, 29: 128-137. PMID: 22956744, DOI: 10.1177/0885066612457339.Peer-Reviewed Original ResearchConceptsMechanical ventilationPrimary respiratory failureTraumatic brain injuryMultiple organ systemsImpact of injuryConcomitant tissue injuryRespiratory failureCritical illnessVentilator strategiesBronchopleural fistulaVentilator managementBrain injuryPhysiologic changesTissue injuryBlast injuryInjuryThermal injuryOrgan systemsPatientsMajor causeVentilationSpecial considerationFistulaIllness
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