2024
Treatment Effect Heterogeneity in Acute Kidney Injury Incidence Following Intravenous Antihypertensive Administration for Severe Blood Pressure Elevation During Hospitalization
Ghazi L, Chen X, Harhay M, Hu L, Biswas A, Peixoto A, Li F, Wilson F. Treatment Effect Heterogeneity in Acute Kidney Injury Incidence Following Intravenous Antihypertensive Administration for Severe Blood Pressure Elevation During Hospitalization. American Journal Of Kidney Diseases 2024, 85: 442-453. PMID: 39580068, DOI: 10.1053/j.ajkd.2024.09.011.Peer-Reviewed Original ResearchAcute kidney injuryAcute kidney injury incidenceSevere hypertensionIV antihypertensivesAntihypertensive treatmentBlood pressureRisk of acute kidney injuryAbstractText Label="SETTINGS &Blood pressure elevationSevere blood pressure elevationSystolic blood pressureIdentifying treatment optionsAntihypertensive administrationKidney injuryAbstractText Label="RATIONALETreatment optionsAntihypertensive effectBP elevationPressure elevationPatient characteristicsDiastolic BPPatientsKidney failureAntihypertensivesHospital admissionSex, Acute Kidney Injury, and Age: A Prospective Cohort Study
Golestaneh L, Basalely A, Linkermann A, El-Achkar T, Kim R, Neugarten J. Sex, Acute Kidney Injury, and Age: A Prospective Cohort Study. American Journal Of Kidney Diseases 2024, 85: 329-338.e1. PMID: 39447957, DOI: 10.1053/j.ajkd.2024.10.003.Peer-Reviewed Original ResearchConceptsRisk of acute kidney injuryAcute kidney injuryFemale sex hormonesSex hormonesKidney injuryRelative risk of acute kidney injuryOdds of acute kidney injuryAnimal models of kidney diseaseRisk factorsAcute kidney injury incidenceHospital-acquired acute kidney injuryWomen of fertile ageModels of kidney diseaseAbstractText Label="PLAIN-LANGUAGE SUMMARYAge groupsEquation logistic regressionSeverity of illnessPostmenopausal womenKDIGO definitionAbstractText Label="RATIONALEObstetric diagnosisAge categoriesMale sexCounts of hospitalizationsMontefiore Health System
2023
Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study
Aziz M, Schenning K, Koike S, O’Glasser A, O’Reilly-Shah V, Sera V, Mathis M, Naik B, Taicher B, Colquhoun D, Freundlich R, Schonberger R, Domino K, Chen L, Pace N. Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study. Anesthesiology 2023, 140: 195-206. PMID: 37844271, DOI: 10.1097/aln.0000000000004809.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPulmonary complicationsKidney injuryIncreased riskPerioperative mortalityExposed patientsCOVID-19 infectionIncreased 30-day mortality riskElective surgeryIncreased risk of acute kidney injuryIncreased risk of pulmonary complicationsRisk of acute kidney injuryMortality riskPositive testRisk of pulmonary complicationsRisk of perioperative mortalityRetrospective observational cohort studyThirty-day mortalityCOVID-19-recovered patientsCohort of patientsExposure to COVID-19 infectionIncreased risk of mortalityAssociated with increased mortality riskObservational cohort studyElective inpatient surgeryCardiometabolic disease and obesity patterns differentially predict acute kidney injury after total joint replacement: a retrospective analysis
Leis A, Mathis M, Kheterpal S, Zawistowski M, Mukherjee B, Pace N, O'Reilly-Shah V, Smith J, Karvonen-Gutierrez C. Cardiometabolic disease and obesity patterns differentially predict acute kidney injury after total joint replacement: a retrospective analysis. British Journal Of Anaesthesia 2023, 131: 37-46. PMID: 37188560, PMCID: PMC10308436, DOI: 10.1016/j.bja.2023.04.001.Peer-Reviewed Original ResearchConceptsOdds of acute kidney injuryAcute kidney injuryCardiometabolic diseasesNon-Hispanic blacksGroup of hospitalsKidney injuryCardiometabolic patternTotal joint arthroplasty complicationsObesity statusObesity patternsIncreased oddsDisease co-occurrenceIncreased odds of AKIRetrospective analysisRisk of postoperative acute kidney injuryLatent class analysisLatent classesPostoperative acute kidney injuryRisk of acute kidney injuryRisk factorsDifferential riskTotal joint replacementMetabolic syndromeObesityPostoperative AKI risk
2020
Acute kidney injury in renal transplant recipients undergoing cardiac surgery
Hundemer G, Srivastava A, Jacob K, Krishnasamudram N, Ahmed S, Boerger E, Sharma S, Pokharel K, Hirji S, Pelletier M, Safa K, Kulvichit W, Kellum J, Riella L, Leaf D. Acute kidney injury in renal transplant recipients undergoing cardiac surgery. Nephrology Dialysis Transplantation 2020, 36: 185-196. PMID: 32892219, PMCID: PMC7771983, DOI: 10.1093/ndt/gfaa063.Peer-Reviewed Original ResearchConceptsRenal transplant recipientsAcute kidney injuryNon-RTRsCardiac surgeryCalcineurin inhibitorsRisk factorsTransplant recipientsKidney injuryType of cardiac surgeryKidney diseaseRates of acute kidney injuryRisk of acute kidney injuryDeceased donorsGlobal Outcomes criteriaLiving donorsRetrospective cohort studyAssociated with higher ratesChronic kidney diseaseTrough levelsClinical characteristicsAcademic medical centerCohort studySurgeryHigh riskMedical CenterClinical efficacy of immunotherapy for the treatment of solid tumors in patients with chronic kidney disease.
Ganta T, Jun T, Qin Q, Patel V, Wang B, Mellgard G, Gogerly-Moragoda M, Leiter A, Gallagher E, Oh W, Galsky M, Tsao C. Clinical efficacy of immunotherapy for the treatment of solid tumors in patients with chronic kidney disease. Journal Of Clinical Oncology 2020, 38: e15109-e15109. DOI: 10.1200/jco.2020.38.15_suppl.e15109.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsChronic kidney diseaseRegulatory T cellsProportion of patientsSolid tumorsT cellsClinical outcomesCancer patients treated with immune checkpoint inhibitorsPatients treated with immune checkpoint inhibitorsEfficacy of immune checkpoint inhibitorsIncidence of renal adverse eventsInhibition of regulatory T cellsTreated with immune checkpoint inhibitorsSingle-institution retrospective cohort studyClinical trialsClinical efficacy of immunotherapyKidney diseaseAssociated with worse clinical outcomesRisk of acute kidney injurySmoking statusPresence of chronic kidney diseasePresence of cardiovascular comorbiditiesTreatment of solid tumorsCancer compared to patientsChronic kidney disease cohort
2019
Characterizing Risks Associated With Mitral Annular Calcification in Mitral Valve Replacement
Kaneko T, Hirji S, Percy E, Aranki S, McGurk S, Body S, Heydarpour M, Mallidi H, Singh S, Pelletier M, Rawn J, Shekar P. Characterizing Risks Associated With Mitral Annular Calcification in Mitral Valve Replacement. The Annals Of Thoracic Surgery 2019, 108: 1761-1767. PMID: 31207248, DOI: 10.1016/j.athoracsur.2019.04.080.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCalcinosisEchocardiography, TransesophagealFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHumansIncidenceIntraoperative ComplicationsMaleMiddle AgedMitral ValvePostoperative ComplicationsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival RateUnited StatesConceptsMitral annular calcificationAssociated with increased operative mortalityPresence of mitral annular calcificationMV replacementOperative mortalityAnnular calcificationSociety of Thoracic Surgeons Adult Cardiac Surgery DatabaseMAC patientsAssociated with increased risk of acute kidney injuryAdult Cardiac Surgery DatabaseRisk of acute kidney injuryMitral valve (MVConcomitant tricuspid proceduresNon-MAC patientsObserved operative mortalityCardiac Surgery DatabaseMitral valve replacementAssociated with increased riskAdverse postoperative outcomesAcute kidney injuryIn-Hospital ComplicationsTricuspid proceduresReoperation rateSurgery DatabaseValve replacement
2018
Sex differences in acute kidney injury requiring dialysis
Neugarten J, Golestaneh L, Kolhe N. Sex differences in acute kidney injury requiring dialysis. BMC Nephrology 2018, 19: 131. PMID: 29884141, PMCID: PMC5994053, DOI: 10.1186/s12882-018-0937-y.Peer-Reviewed Original ResearchConceptsAcute kidney injuryKidney injuryFemale sexKidney Disease Improving Global Outcomes Clinical Practice GuidelineHospital-associated acute kidney injuryGlobal Outcomes Clinical Practice GuidelineIncidence of acute kidney injuryRisk of acute kidney injuryAssociated with cardiac surgeryAKI-DHospital-acquired acute kidney injuryPopulation of hospitalized patientsContrast-induced nephropathyRenal replacement therapyHospital Episode Statistics databaseDialysis practiceClinical practice guidelinesAminoglycoside nephrotoxicityCardiac surgeryReplacement therapyPublished cohortMale sexBackgroundFemale sexIncreased incidenceReno-protection
2016
Blood Transfusion and the Risk of Acute Kidney Injury Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Karrowni W, Vora A, Dai D, Wojdyla D, Dakik H, Rao S. Blood Transfusion and the Risk of Acute Kidney Injury Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2016, 9 PMID: 27582110, DOI: 10.1161/circinterventions.115.003279.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAcute Kidney InjuryAgedAnemiaBiomarkersBlood TransfusionChi-Square DistributionCreatinineFemaleHemoglobinsHemorrhageHumansLogistic ModelsMaleMiddle AgedOdds RatioPercutaneous Coronary InterventionPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTransfusion ReactionTreatment OutcomeUnited StatesUp-RegulationConceptsAcute kidney injuryPercutaneous coronary interventionRisk of acute kidney injurySubgroup of patientsBlood transfusionAcute coronary syndromeKidney injuryCoronary syndromeAssociated with acute kidney injuryRates of acute kidney injuryAssociation of blood transfusionAssociated with adverse clinical outcomesCoronary interventionAdvanced stages of chronic kidney diseaseRestrictive blood transfusion strategyComplicating percutaneous coronary interventionStages of chronic kidney diseaseImprove PCI outcomesPreprocedural hemoglobin levelNo blood transfusionAdverse clinical outcomesRetrospective cohort studyBlood transfusion strategyChronic kidney diseasePrevalence of comorbidities
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