2025
Current Landscape of Children's Surgery in Africa: A Multicenter Analysis of 16,000 Cases
Hsu P, Carroll M, Zambeli‐Ljepovic A, Olatunji‐Banire B, Mathew P, Axt J, Diallo T, Eshete M, Ki B, Macharia J, Ngock G, Serawit A, Bryce E, Ozgediz D, Cheung M. Current Landscape of Children's Surgery in Africa: A Multicenter Analysis of 16,000 Cases. World Journal Of Surgery 2025 PMID: 40913246, DOI: 10.1002/wjs.70066.Peer-Reviewed Original ResearchSurgical careBurden of pediatric surgical diseaseChildren's surgical careHousehold-based surveyMiddle-income countriesBurden of diseasePediatric surgical carePerioperative clinical dataAssociated with much higher ratesHigher mortalityPediatric surgical diseasesFrequency of proceduresEffective interventionsYoung childrenChildren’s SurgeryMulticenter analysisIntestinal perforationCongenital malformationsGlobal disparitiesCareElective operationsClinical dataCongenital conditionSurgical proceduresSurgical diseaseComparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer
Gao X, Wright N, Huard M, Tan J, Ruzbarsky J, Lu A, Chubb L, Tuan R, Philippon M, Wang Y, Huard J. Comparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer. Bioactive Materials 2025, 52: 588-603. PMID: 40607117, PMCID: PMC12219002, DOI: 10.1016/j.bioactmat.2025.06.031.Peer-Reviewed Original ResearchChondrogenic differentiation of human bone marrow mesenchymal stem cellsTreatment of cartilage defectsCartilage defect repairFibrocartilage repairCartilage repairChondrogenic potentialCartilage defectsSustained release polymerChondrogenic differentiationHuman bone marrow mesenchymal stem cellsDifferentiation of human bone marrow mesenchymal stem cellsRelease polymersBone marrow mesenchymal stem cellsMarrow mesenchymal stem cellsSurgical proceduresClinical challengeMesenchymal stem cellsDefect repairStem cellsMorphogenetic proteinsOsteoarthritis treatmentRepairTreatmentPolymerMicrofractureOutcomes of Concomitant Hip Arthroscopic Surgery for Intra-articular Abnormalities and Endoscopic Abductor Tendon Repair at a Minimum 2-Year Follow-up: A Systematic Review
Gagné J, Lee M, Patel S, Klug T, Monahan P, Park N, Surucu S, Gillinov S, Moran J, Jimenez A. Outcomes of Concomitant Hip Arthroscopic Surgery for Intra-articular Abnormalities and Endoscopic Abductor Tendon Repair at a Minimum 2-Year Follow-up: A Systematic Review. Orthopaedic Journal Of Sports Medicine 2025, 13: 23259671251341479. PMID: 40496596, PMCID: PMC12149625, DOI: 10.1177/23259671251341479.Peer-Reviewed Original ResearchHip arthroscopic surgeryPostoperative patient-reported outcome measuresAbductor tendon repairSecondary surgical proceduresIntra-articular abnormalitiesSurgical proceduresArthroscopic surgerySecondary surgeryFollow-upSystematic reviewTendon repairRate of secondary surgeryTreatment of labral tearsConcomitant surgical proceduresFollow-up timeRate of secondary surgical proceduresOutcome measuresPostoperative time pointsMeasures of clinical benefitPreoperative radiographic findingsAbductor tendon tearsLevel of evidencePatient-reported outcome measuresLabral treatmentNo significant differenceLinear and Area Coverage With Closed Incision Negative Pressure Therapy Management: International Multidisciplinary Consensus Recommendations
Singh D, Alton T, Alvand A, de Toledo P, Chatterjee A, Dillavou E, Djohan R, Ortega A, Pieri A, Sumpio B, Willy C, Zelle B, Cooper H. Linear and Area Coverage With Closed Incision Negative Pressure Therapy Management: International Multidisciplinary Consensus Recommendations. International Wound Journal 2025, 22: e70677. PMID: 40432310, PMCID: PMC12117191, DOI: 10.1111/iwj.70677.Peer-Reviewed Original ResearchConceptsClosed incision negative pressure therapyReticulated open cell foamReticulated open cell foam dressingConsensus statementMultidisciplinary consensus recommendationsImprove surgical outcomesNegative pressure therapyMultidisciplinary panel of expertsIncision typeSurgical outcomesPressure therapyIncision healingSurgical proceduresClinician decision-makingConsensus recommendationsRisk factorsConsensus panelPanel of expertsMultidisciplinary panelFoam dressingTherapy managementIncisionMultidisciplinary collaborationPatient careGender-Affirming Surgery for Transgender and Gender Diverse Medicare Beneficiaries
Balkan E, Babbs G, Meyers D, Kelly P, Yee K, Pletta D, Shireman T, Alpert A, Baker K, Hughto J. Gender-Affirming Surgery for Transgender and Gender Diverse Medicare Beneficiaries. JAMA Network Open 2025, 8: e258072. PMID: 40310645, PMCID: PMC12046427, DOI: 10.1001/jamanetworkopen.2025.8072.Peer-Reviewed Original ResearchConceptsGender-affirming surgeryTransgender individualsRates of chronic conditionsTransgenderBeneficiaries' useProportion of residentsRegional differencesDual statusBeneficiariesChronic conditionsDiverse beneficiariesBeneficiary characteristicsMedicare beneficiariesGenderCross-sectional studyMedicare entitlementGender-affirming surgical proceduresPropensity score matchingNational Medicare dataMedicare programMedicaidProportion of Medicare beneficiariesSouthSurgical proceduresDescriptive analysisAbstract We0072: Matrix metalloproteinases-3 promotes arteriovenous fistula failure by regulating FAK-AKT signaling
Xie Y, Zhang W, Thaxton C, Jin Y, Yatsula B, Davis S, Exsted T, Dardik A, Guzman R, Cai Y. Abstract We0072: Matrix metalloproteinases-3 promotes arteriovenous fistula failure by regulating FAK-AKT signaling. Arteriosclerosis Thrombosis And Vascular Biology 2025, 45: awe0072-awe0072. DOI: 10.1161/atv.45.suppl_1.we0072.Peer-Reviewed Original ResearchMatrix metalloproteinases-3Arteriovenous fistulaNeointimal hyperplasiaSMC proliferationMetalloproteinases-3Aggressive neointimal hyperplasiaArteriovenous fistula creationArteriovenous fistula failureCell growth in vitroSignaling pathwayVenous SMCsGrowth in vitroNeointimal SMCsMolecular signaling pathwaysFistula failureIncreased morbiditySurgical proceduresVenous SMC proliferationRodent modelsTherapeutic strategiesVascular accessImproved patencyGrowth factors PDGF-BBHyperplasiaPDGF-BBA narrative review on multimodal spinal anesthesia: Old technique and new use
Pierson D, Certoma R, Hobbs J, Cong X, Li J. A narrative review on multimodal spinal anesthesia: Old technique and new use. Journal Of Anesthesia And Translational Medicine 2025, 4: 25-32. PMID: 40321954, PMCID: PMC12048027, DOI: 10.1016/j.jatmed.2025.02.002.Peer-Reviewed Original ResearchEP3.5 Patients Undergoing Concomitant Hip Arthroscopy for Intra-Articular Pathology and Endoscopic Abductor Tendon Repair Demonstrate Favorable Outcomes at Short-Term Follow-Up: A Systematic Review
Gagne J, Lee M, Patel S, Klug T, Monahan P, Park N, Surucu S, Jimenez A. EP3.5 Patients Undergoing Concomitant Hip Arthroscopy for Intra-Articular Pathology and Endoscopic Abductor Tendon Repair Demonstrate Favorable Outcomes at Short-Term Follow-Up: A Systematic Review. Journal Of Hip Preservation Surgery 2025, 12: i70-i71. PMCID: PMC11953835, DOI: 10.1093/jhps/hnaf011.226.Peer-Reviewed Original ResearchPostoperative patient-reported outcomesAbductor tendon repairShort-term follow-upConcomitant hip arthroscopyHip arthroscopyIntra-articular pathologySecondary surgeryPostoperative PROsFollow-upSurgical proceduresRate of secondary surgeryTendon repairFemoroacetabular impingementSystematic reviewTreatment of labral tearsControl group of patientsConcomitant surgical proceduresCochrane Central Register of Controlled TrialsOutcomes of patientsCentral Register of Controlled TrialsFollow-up timeSecondary surgical proceduresPostoperative time pointsRegister of Controlled TrialsGroup of patientsThe role of right ventricular systolic pressure and ARISCAT score in perioperative pulmonary risk assessment
Tatsuoka Y, He Z, Lin H, Notarianni A, Carr Z. The role of right ventricular systolic pressure and ARISCAT score in perioperative pulmonary risk assessment. Brazilian Journal Of Anesthesiology 2025, 75: 844597. PMID: 39971234, PMCID: PMC11914786, DOI: 10.1016/j.bjane.2025.844597.Peer-Reviewed Original ResearchConceptsRight ventricular systolic pressurePostoperative pulmonary complicationsArea under the curveARISCAT scoreVentricular systolic pressureReceiver operating characteristic curvePulmonary hypertensionRespiratory failureHigh-risk populationPrimary endpointRisk stratificationSurgical proceduresSystolic pressurePostoperative pulmonary complications incidenceSource of increased morbidityAssess Respiratory RiskDiagnosis of PHPreoperative risk assessmentAdjusted multivariable logistic regression modelsMultivariate logistic regression modelComposite of pneumoniaPulmonary complicationsPreoperative investigationsSecondary endpointsPulmonary aspirationAccuracy of point-of-care ultrasound in diagnosing retained products of conception
Boivin Z, Barber D, Chimileski B, Fetherston T, Li J, Liu R, Moore C. Accuracy of point-of-care ultrasound in diagnosing retained products of conception. The American Journal Of Emergency Medicine 2025, 90: 65-70. PMID: 39826241, DOI: 10.1016/j.ajem.2025.01.032.Peer-Reviewed Original ResearchConceptsRetained Products of ConceptionObstetrics and GynecologyPoint-of-care ultrasoundAccuracy of point-of-care ultrasoundProducts of conceptionChart reviewRadiology ultrasoundTransabdominal point-of-care ultrasoundEmergency departmentTest characteristics of point-of-care ultrasoundRetrospective cohort studyPoint-of-care ultrasound examinationPoint-of-care ultrasound imagingGold standard diagnosisIndeterminate examinationsIntrauterine pregnancyIntrauterine tissuesUltrasound fellowsPregnancy terminationEarly pregnancyFemale patientsSurgical proceduresNonblinded investigationCohort studyPOCUS examinationsCirrhosis and Truly Elective Major Surgery
Jakab S, Oprea A. Cirrhosis and Truly Elective Major Surgery. 2025, 249-258. DOI: 10.1093/med/9780190902001.003.0021.Peer-Reviewed Original ResearchPrevalence of chronic liver diseasePerioperative management of patientsPreoperative risk evaluationPresence of cirrhosisType of surgeryComplications of cirrhosisManagement of patientsEfficacy of therapyChronic liver diseaseLiver synthetic dysfunctionSynthetic dysfunctionOverall prognosisPostoperative complicationsDiagnosing cirrhosisPortal hypertensionLiver transplantationPerioperative managementPatient comorbiditiesSurgical proceduresCirrhosisLiver diseasePatientsSurgical teamScoring systemSurgery
2024
POLYGENIC RISK SCORE FOR DIABETES PREDICTS POSTOPERATIVE ACUTE KIDNEY INJURY
Leis A, Mathis M, Smith J, Mukherjee B, Karvonen-Gutierrez C. POLYGENIC RISK SCORE FOR DIABETES PREDICTS POSTOPERATIVE ACUTE KIDNEY INJURY. Innovation In Aging 2024, 8: 132-133. PMCID: PMC11689292, DOI: 10.1093/geroni/igae098.0427.Peer-Reviewed Original ResearchPolygenic risk scoresAcute kidney injuryKidney Disease-Improving Global OutcomesOdds of acute kidney injuryPostoperative acute kidney injuryPredicting postoperative acute kidney injuryRisk scoreKidney injuryAcute kidney injury prevalenceLogistic regression modelsOlder adultsT2DM statusType 2 diabetesInformation biasPRS modelTransplant surgical proceduresAnalysis of outcomesGenetic cohortsDiabetes statusLowest decileIntraoperative factorsNon-cardiacNon-renalNon-urologicalSurgical proceduresPreoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion
Katsnelson B, Rancu A, Winter A, Grauer J. Preoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00204. PMCID: PMC11473058, DOI: 10.5435/jaaosglobal-d-24-00204.Peer-Reviewed Original ResearchRevision surgery ratesAnterior cervical diskectomyAdverse eventsACDF patientsCervical diskectomySurgery ratesSingle-level anterior cervical diskectomyAdverse outcomesPreoperative anxietyCervical spine surgeryIncreased reoperation rateAssociated with adverse eventsFusion (ACDFSingle-level ACDFPostoperative adverse eventsPrevalence of mental health disordersImportant risk factorsMultivariate regression analysisReoperation rateMental health disordersSpine surgerySurgical outcomesElixhauser Comorbidity IndexHistory of anxietySurgical proceduresAssociation between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study
Douville N, Smolkin M, Naik B, Mathis M, Colquhoun D, Kheterpal S, Collins S, Martin L, Popescu W, Pace N, Blank R, Committee M, Aziz M, Blasberg J, Chang A, Freundlich R, O’Reilly-Shah V, Schonberger R. Association between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study. British Journal Of Anaesthesia 2024, 133: 1073-1084. PMID: 39266439, PMCID: PMC11619793, DOI: 10.1016/j.bja.2024.08.005.Peer-Reviewed Original ResearchPostoperative pulmonary complicationsOne-lung ventilationAssociated with postoperative pulmonary complicationsInspired oxygen fractionPulmonary complicationsThoracic surgeryLogistic regression modelsDevelopment of postoperative pulmonary complicationsIntraoperative inspired oxygen fractionDuration of one-lung ventilationReduce postoperative pulmonary complicationsMulticentre retrospective cohort studyComposite of postoperative pulmonary complicationsUS medical centresLung resection surgeryRetrospective multicentre studyThoracic surgical proceduresArea under the curveRetrospective cohort studyOxygen fractionExposure of interestResection surgeryMulticentre studyUnivariate analysisSurgical procedures(258) VASECTOMY ON TIKTOK: AN ANALYSIS OF THE TOP 50 VIDEOS
Cahill E, Reddy S, Rotker K, Honig S. (258) VASECTOMY ON TIKTOK: AN ANALYSIS OF THE TOP 50 VIDEOS. The Journal Of Sexual Medicine 2024, 21: qdae167.251. DOI: 10.1093/jsxmed/qdae167.251.Peer-Reviewed Original ResearchPost-vasectomy semen analysisPhysician usersVideo contentSource of videosVideo informationUser postsSocial mediaVideo lengthUsersVideoAnalyzed videosTikTok usersVideo engagementNon‐physician usersSemen analysisNon-physiciansSurgical proceduresCounseling patientsInformationPermanent sterilizationTikTokVasectomyEffective procedurePatientsTikTok videosAnesthetic Considerations for Gender-Affirming Airway and Facial Procedures.
Amendola S, Stemmler N, Cosgrove M, Ruggiero F. Anesthetic Considerations for Gender-Affirming Airway and Facial Procedures. AANA Journal 2024, 92: 303-311. PMID: 39056500.Peer-Reviewed Original ResearchConceptsTransgender patientsFacial proceduresVocal cord damageAssociated with administrationAdvanced airway techniquesGender-affirming proceduresNovel surgical procedureGender-affirming surgeryHormone therapyAdministration of hormonesThromboembolic eventsAirway surgeryGender goalsMedical therapyExperience incongruenceLaboratory valuesCord damageGender identitySurgical proceduresAirway techniquesAnesthetic considerationsTracheal stenosisCardiovascular effectsIncreased riskPerioperative challengesLeveraging machine learning to develop a postoperative predictive model for postoperative urinary retention following lumbar spine surgery
Malnik S, Porche K, Mehkri Y, Yue S, Maciel C, Lucke-Wold B, Robicsek S, Decker M, Busl K. Leveraging machine learning to develop a postoperative predictive model for postoperative urinary retention following lumbar spine surgery. Frontiers In Neurology 2024, 15: 1386802. PMID: 38988605, PMCID: PMC11233696, DOI: 10.3389/fneur.2024.1386802.Peer-Reviewed Original ResearchPostoperative urinary retentionLumbar spine surgerySpine surgeryUrinary retentionPatient demographicsIncidence of postoperative urinary retentionRetrospective observational cohort studyTertiary academic medical centerIndwelling catheter placementIncreased patient morbidityReceiver operating characteristic curveArea under the receiver operating characteristic curveObservational cohort studyAcademic medical centerBody mass indexPostoperative prediction modelLogistic regression modelsIntraoperative variablesIntraoperative factorsCatheter placementAnesthesia variablesPatient morbidityMass indexSurgical proceduresCohort studyPreoperative medication management turnkey order set for nonemergent adult cardiac surgery
Rea A, Salenger R, Grant M, Yeh J, Damas B, Crisalfi C, Arora R, Gregory A, Morton-Bailey V, Engelman D, Group E, Cangut B, Chatterjee S, Lobdell K, McConnell G, Crotwell S, Reddy S. Preoperative medication management turnkey order set for nonemergent adult cardiac surgery. JTCVS Open 2024, 22: 1-13. PMID: 39780789, PMCID: PMC11704528, DOI: 10.1016/j.xjon.2024.06.009.Peer-Reviewed Original ResearchSodium-glucose co-transporter-2Adult cardiac surgeryPreoperative medical managementGlucagon-like peptide-1Cardiac surgeryConsensus manuscriptNon-emergent cardiac surgeryMedical managementClass ICardiac surgical patientsCardiac surgical proceduresRisk of bleedingExpert consensus documentPreoperative managementPreoperative medicationsAnticoagulant medicationSurgical patientsSurgical proceduresSurgeryAnti-plateletPeptide-1Perioperative careConsensus documentCardiac SocietyManagement of patients' medicationPartial Hepatectomy and Ablation for Survival of Early-Stage Hepatocellular Carcinoma Patients: A Bayesian Emulation Analysis
Wang J, Im Y, Wang R, Ma S. Partial Hepatectomy and Ablation for Survival of Early-Stage Hepatocellular Carcinoma Patients: A Bayesian Emulation Analysis. Life 2024, 14: 661. PMID: 38929645, PMCID: PMC11204969, DOI: 10.3390/life14060661.Peer-Reviewed Original ResearchOverall survivalHepatocellular carcinomaPartial hepatectomyTumor sizeAssociated with inferior overall survivalEarly-stage hepatocellular carcinomaEarly-stage HCC patientsInferior overall survivalHepatocellular carcinoma patientsAblation armCarcinoma patientsAblation therapyNo significant differenceTreatment regimensHCC patientsEmulated target trialSurgical proceduresEffect of ablationHepatectomyPatientsCompare treatment effectsClinical treatmentSignificant differencePropensity scoreLogistic regressionAcquired, Lesional Lennox-Gastaut Syndrome
Herlopian A. Acquired, Lesional Lennox-Gastaut Syndrome. 2024, 919-943. DOI: 10.1007/978-3-031-23828-4_37.Peer-Reviewed Original ResearchCentromedian nucleusConfirm electrode placementGeneralized atonic seizuresLennox-Gastaut syndromeCentromedian thalamic nucleusLanguage lateralizationPost-operative language deficitsRare entityLennox-GastautCorpus callosotomySurgical interventionCortical malformationsAtonic seizuresSurgical proceduresThalamic nucleiCorpus callosumEpileptic networkDeep brain stimulation devicesLanguage deficitsNeurostimulation devicesElectrode placementPatientsNeurophysiological recordingsEpilepsyLanguage
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